Cumulative Socioeconomic Status across the Life Course and Subclinical Athersclerosis
Carson, April P.; Rose, Kathryn M.; Catellier, Diane. J; Kaufman, J.; Wyatt, Sharon B.; Diez Roux, Ana V.; Heisss, G.
2007
View/ Open
Cumulative Socioeconomic Status across the Life Course and Subclinical Atherosclerosis.pdf

(118.1KB
PDF)
Citation
Annals of Epidemiology Volume 17, Issue 4, April 2007, Pages 296-303 <http://hdl.handle.net/2027.42/57757>
Abstract
Purpose The purpose of this study is to investigate the relationship between individual-level and neighborhood-level socioeconomic status (SES) across the life course and subclinical atherosclerosis. Methods Participants from the Atherosclerosis Risk in Communities Study (n = 12,332) were queried about individual-level SES and residential addresses across the life course. Individual-level measures were scored and summed to obtain a summary score (I-CumSES), whereas residential addresses were geocoded and linked to census data to obtain a summary neighborhood z score (N-CumSES) to evaluate the association of SES with intima-media thickness (IMT) and peripheral arterial disease (PAD). Results A 1-SD lower I-CumSES was associated with greater mean IMT in each race–sex group and greater odds of PAD in white men (odds ratio [OR], 1.28; 95% confidence interval [CI], 0.99–1.64), white women (OR, 1.18; 95% CI, 1.02–1.36), and black women (OR, 1.33; 95% CI, 1.00–1.76). Compared with the highest tertile of N-CumSES, the lowest tertile was associated with greater mean IMT among whites, but was not associated with PAD for whites or blacks. When I-CumSES and N-CumSES were considered simultaneously, associations remained for only I-CumSES and were attenuated after adjustment for cardiovascular disease (CVD) risk factors. Conclusions Lower cumulative individual-level SES across the life course was associated with a greater burden of subclinical atherosclerosis, and this association was mediated in part by CVD risk factors.Types
Article
Metadata
Show full item recordAccessibility: If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.