Now showing items 11-20 of 42
Steady state levels of pro-dynorphin-related end products in the striatum and substantia nigra of the adult rhesus monkey
(Elsevier, 1985)
Analysis of an acid extract of the striatum of the rhesus monkey revealed that the molar ratio of dynorphin A(1-8)-sized material and dynorphin (A(1-17)-sized material is approximately 1:1. In addition, the molar ratios ...
Paradoxical effect of corticosteroids on pituitary ACTH/[beta]-endorphin release in stressed animals
(Elsevier, 1988)
We have previously demonstrated a number of changes in the anterior lobe proopiomelanocortin (POMC) system in chronically stressed rats. The purpose of the present experiments was to investigate whether chronically stressed ...
Fever and leukocytosis: Physical manifestations of bipolar affective disorder?
(Elsevier, 1988)
1. 1. Fever and leukocytosis are occasionally observed in patients with psychiatric disorders. A thorough medical evaluation does not always reveal the origin of these abnormalities.2. 2. We report the case histories of ...
The effect of amphetamine on plasma cortisol in patients with endogenous and non-endogenous depression
(Elsevier, 1981)
Amphetamine sulphate (0.1 mg/kg, i.v.) produced no consistent change in plasma cortisol levels in 21 depressed patients. Seven patients with endogenous depression (melancholia) were matched with seven patients with ...
Behavioral effects of dynorphin1-13 in the mouse and rat: Initial observations
(Elsevier, 1980)
Dynorphin is a recently identified, pharmacologically potent endogenous opioid peptide. Heretofore it has not been characterized for its behavioral effects. The effects of centrally infused dynorphin upon a variety of ...
[D-Ala2,(F5)Phe4]-dynorphin1-13-NH2 (DAFPHEDYN): A potent analog of dynorphin 1-13
(Elsevier, 1987)
Intracerebroventricular administration of the dynorphin analog, [D-Ala2,(F5)Phe4]-dynorphin1-13-NH2 (DAFPHEDYN) in rats produced diuresis and profound analgesia. Both effects were antagonized by central administration of ...
Gamma-melanotropin response to ovine corticotropin releasing factor in normal humans
(Elsevier, 1987)
Plasma [gamma]-melanotropin was measured by a [gamma]3MSH-specific radioimmunoassay before and after a single bolus intravenous infusion of ovine corticotropin releasing factor (oCRF; 0.1 ug/kg) in seven normal men. A ...
ω- 123 I-Hexadecanoic acid metabolic probe of cardiomypathy
(Springer-Verlag, 1985-03)
The utility of ω- 123 I-hexadecanoic acid myocardial scintigraphy as a metabolic probe of cardiomyopathies was investigated. Sixteen patients with a variety of cardiomyopathies and myopathies that involve cardiac muscle ...
Interaction of opiate peptide and noradrenalin systems: Light microscopic studies
(Elsevier, 1980)
In this light microscopic immunocyto-chemical study [beta]-Endorphin ([beta]-END), leu-enkephalin and dopamine-[beta]hydroxylase (DBH) antisera are used to obtain an overview of the interaction of the noradrenergic and ...
Phobic anxiety does not affect plasma levels of thyroid stimulating hormone in man
(Elsevier, 1982)
(1) The effect of anxiety on plasma levels of thyroid stimulating hormone (TSH) is not clear, despite a number of relevant studies. (2) Nine human subjects with severe phobias had blood samples taken for TSH assay every ...