Now showing items 11-20 of 39
Individual differences in sensitivity to nicotine: Implications for genetic research on nicotine dependence
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1995-03)
Recent evidence suggests that cigarette smoking has a heritability index around 53%. While related research on underlying mechanisms also supports the idea that genetic factors contribute to nicotine dependence—as well as ...
Telemetric measurement of core temperature in pharmacological research: Validity and reliability
(Elsevier, 1990)
1. The authors present data establishing the reliability and validity of a method for telemetrically measuring core temperature.2. The method is designed to be of particular utility to psychobiological researchers.
Euphoriant effects of nicotine in smokers
(Springer-Verlag, 1992-09)
Two studies were conducted to replicate and extend previous demonstrations of smoking-induced, dose-related reports of euphoria, and to confirm this relationship using measures of plasma nicotine. In experiment 1, ...
Multiple steroid hormone levels in depressed patients and normal controls before and after exogenous ACTH
(Elsevier, 1991)
Forty depressed patients and 36 age- and sex-matched controls were given 250 [mu]g ACTH1-24 by bolus. Plasma steroid hormone levels were measured prior to and 60 min after ACTH administration. The depressed patients had ...
Nicotine may relieve symptoms of Parkinson's disease
(Springer-Verlag, 1994-09)
Two elderly patients with Parkinson's disease were treated with nicotine gum and patch. Reliable changes in symptomatology were noted, using a single-subject, placebo-control reversal design. Improvement was associated ...
Distribution of D2 dopamine receptor mRNA in the primate brain
(Elsevier, 1991)
1. The distribution of the messenger RNA (mRNA) encoding the D2dopamine receptor has been mapped in the monkey brain by hybridization.2. Using [35s]-labelled riboprobes corresponding to the region of the D2 dopamine ...
In Vitro release of hypothalamic [beta]-endorphin [beta]E by arginine vasopressin, corticotropin-releasing hormone and 5-hydroxytryptamine: Evidence for release of opioid active and inactive [beta]E forms
(Elsevier, 1990-05)
The aims of the present experiments were: 1) to test whether substances which modulate beta-endorphin-immunoreactive [beta]E-ir release from the pituitary gland might act similarly in hypothalamic tissue; and 2) to further ...