Now showing items 11-20 of 28
Gamma-melanotropin response to ovine corticotropin releasing factor in normal humans
(Elsevier, 1987)
Plasma [gamma]-melanotropin was measured by a [gamma]3MSH-specific radioimmunoassay before and after a single bolus intravenous infusion of ovine corticotropin releasing factor (oCRF; 0.1 ug/kg) in seven normal men. A ...
Analysis of opioid and non-opioid end products of pro-dynorphin in the substantia nigra of the rat
(Elsevier, 1985-02)
The substantia nigra is among the richest pro-dynorphin terminal field regions in the rat brain. We therefore contrasted processing in this area to the known processing in the posterior pituitary. Fractionation of acid ...
In Vitro release of hypothalamic [beta]-endorphin [beta]E by arginine vasopressin, corticotropin-releasing hormone and 5-hydroxytryptamine: Evidence for release of opioid active and inactive [beta]E forms
(Elsevier, 1990-05)
The aims of the present experiments were: 1) to test whether substances which modulate beta-endorphin-immunoreactive [beta]E-ir release from the pituitary gland might act similarly in hypothalamic tissue; and 2) to further ...
[kappa]1 Receptor mRNA Distribution in the Rat CNS: Comparison to [kappa] Receptor Binding and Prodynorphin mRNA
(Elsevier, 1994-04)
Three opioid receptor types have been identified in the CNS and periphery that are referred to as [mu], [delta], and [kappa]. The present study examines the mRNA distribution of the [kappa]1 receptor in the rat brain and ...
Anatomical and biochemical studies of the opioid peptides and related substances in the brain
(Elsevier, 1980)
It is now clear that there are at least four opioid peptide-neuronal systems in mammalian brain: the enkephalins, beta-endorphin and dynorphin. The focus of this presentation will be twofold--to focus on the multiple ...
Cloning and expression of the A 2a adenosine receptor from guinea pig brain
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
A full-length complementary DNA (cDNA) clone encoding the guinea pig brain A 2 adenosine receptor has been isolated by polymerase chain reaction (PCR) and low-stringency-hybridization screening of a guinea pig brain cDNA ...
Changes in releasability of ACTH and Beta-endorphin with chronic stress
(Elsevier, 1985-02)
The activation of the hypothalamic pituitary adrenal axis by stress is well-known. Using inescapable intermittent footshock as a stressor in rats, we have previously demonstrated a rise in circulating plasma Beta-endorph ...
Characterization of pro-opiomelanocortin processing in heterologous neuronal cells that express PC2 mRNA
(Elsevier, 1993-05)
We have investigated processing of monkey pro-opiomelanocortin (POMC) following transfection into heterologous neuronal Neuro 2A (N2A) cells. In several separately transfected stable cell lines (termed N2A/POMC2-like; N = ...
Cloning and characterization of a pharmacologically distinct A1 adenosine receptor from guinea pig brain
(Elsevier, 1994-10)
Three full-length cDNA clones encoding the guinea pig A1 adenosine receptor have been isolated by polymerase chain reaction (PCR) and low-stringency hybridization screening of a guinea pig brain cDNA library. These three ...
Social defeat alters the acquisition of cocaine self-administration in rats: role of individual differences in cocaine-taking behavior
(Springer-Verlag, 2001-12)
Rationale : It is known that social defeat can modulate cocaine self-administration. However, it is unclear whether this psychosocial stressor affects drug-taking behavior to the same extent across all individual animals, ...