Now showing items 41-50 of 56
Controlled dosing of nicotine via an I ntranasal N icotine A erosol D elivery D evice (INADD)
(Springer-Verlag, 1992-09)
The present report describes an I ntranasal N icotine A erosol D elivery D evice (INADD) employing an artist's airbrush as aerosolizer and precise, electromechanical control of spray duration. It was designed for the ...
Social defeat alters the acquisition of cocaine self-administration in rats: role of individual differences in cocaine-taking behavior
(Springer-Verlag, 2001-12)
Rationale : It is known that social defeat can modulate cocaine self-administration. However, it is unclear whether this psychosocial stressor affects drug-taking behavior to the same extent across all individual animals, ...
A statistical approach for classifying change in cognitive function in individuals following pharmacologic challenge: an example with alprazolam
(Springer-Verlag, 2006-05)
The effects of any drug treatment on cognitive function are typically studied in groups of subjects. Observations made about the behavior of the drug, in the study sample, are then generalized to the population from which ...
The degradation of dynorphin A in brain tissue in vivo and in vitro
(Elsevier, 1987)
The demonstration of analgesia following in vivo administration of dynorphin A (Dyn A) has been difficult. In contrast, a number of electrophysiological and behavioral effects reported with in vivo injection of Dyn A can ...
Further characterization of the extra-arcuate alpha-melanocyte stimulating hormone-like material in hypothalamus: Biochemical and anatomical studies
(Elsevier, 1986-04)
Previous studies had shown the existence of an extra-arcuate cell group in lateral hypothalamus which contains alpha-melanocyte stimulating hormone (a-MSH)-like immunoreactivity, but no other pro-opiomelanocortin (POMC) ...
Immunocytochemistry of the C-terminal peptide of propressophysin (CPP): Relationship to vasopressin, oxytocin and neurophysin
(Elsevier, 1983-07)
Arginine-vasopressin (AVP) and its associated neurophysin (AVP-NP) are synthesized via a precursor, propressophysin, which also contains a 39 amino acid glycopeptide at its C-terminus (C-terminus of propressophysin, or ...
Acute systemic administration of morphine selectively increases mu opioid receptor binding in the rat brain
(Elsevier, 1984-12)
Opioid receptor binding, including the mu, delta, and kappa receptor subtypes, was compared in morphine-injected and control rats. Brain tissues were homogenized and centrifuged either one or two times prior to receptor ...
Effects of contextual or olfactory cues previously paired with morphine withdrawal on behavior and pain sensitivity in the rat
(Springer-Verlag, 2001-08)
Rationale: Pavlovian conditioning processes have been accorded an important role in maintaining persistent opiate administration. At least one locus for this contribution is during opiate withdrawal. These experiments ...
Dynorphin immunocytochemistry in the rat central nervous system
(Elsevier, 1982)
The distribution of dynorphin in the central nervous system was investigated in rats pretreated with relatively high doses (300-400 [mu]g) of colchicine administered intracerebroventricularly. To circumvent the problems ...
Expression of behavioral sensitization to ethanol by DBA/2J mice: the role of NMDA and non-NMDA glutamate receptors
(Springer-Verlag, 2003-05)
Rationale. Behavioral sensitization has been accorded a central role in contemporary theories of drug addiction. Accordingly, a substantial effort has been made to determine the processes mediating sensitization to ...