Now showing items 11-19 of 19
Cloning and expression of the A 2a adenosine receptor from guinea pig brain
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
A full-length complementary DNA (cDNA) clone encoding the guinea pig brain A 2 adenosine receptor has been isolated by polymerase chain reaction (PCR) and low-stringency-hybridization screening of a guinea pig brain cDNA ...
A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques
(Elsevier, 1991)
D1, a subtype of the dopamine receptors, is widely distributed in the nervous system and has been shown to be positively coupled to adenylate cyclase. Using a combination of in vitro receptor autoradiographic and in situ ...
Opioid receptor-like (ORL1) receptor distribution in the rat central nervous system: Comparison of ORL1 receptor mRNA expression with 125 I-[ 14 Tyr]-orphanin FQ binding
(John Wiley & Sons, Inc., 1999-10-04)
The recently discovered neuropeptide orphanin FQ (OFQ), and its opioid receptor-like (ORL1) receptor, exhibit structural features suggestive of the μ, κ, and δ opioid systems. The anatomic distribution of OFQ immunoreactivity ...
Characterization of pro-opiomelanocortin processing in heterologous neuronal cells that express PC2 mRNA
(Elsevier, 1993-05)
We have investigated processing of monkey pro-opiomelanocortin (POMC) following transfection into heterologous neuronal Neuro 2A (N2A) cells. In several separately transfected stable cell lines (termed N2A/POMC2-like; N = ...
Evidence that [beta]-endorphin is synthesized in cells in the nucleus tractus solitarius: detection of POMC mRNA
(Elsevier, 1992-08-07)
Evidence from a number of sources indicates that the major site of pro-opiomelanocortin (POMC)-producing cells in the CNS is the arcuate nucleus of the hypothalamus. Using immunocytochemical techniques, a second, smaller ...
Cloning and characterization of a pharmacologically distinct A1 adenosine receptor from guinea pig brain
(Elsevier, 1994-10)
Three full-length cDNA clones encoding the guinea pig A1 adenosine receptor have been isolated by polymerase chain reaction (PCR) and low-stringency hybridization screening of a guinea pig brain cDNA library. These three ...
The Role of the Hippocampal Mineralocorticoid and Glucocorticoid Receptors in the Hypothalamo-Pituitary-Adrenal Axis of the Aged Fisher Rat
(Elsevier, 1994-10)
The aging process has been frequently associated with hippocampal neuredegeneration, loss of corticosteroid receptors, and, at the same time, dysfunction of the hypothalamo-pituitary-adrenal (HPA) axis. We were interested ...
Selective forebrain fiber tract lesions implicate ventral hippocampal structures in tonic regulation of paraventricular nucleus corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) mRNA expression
(Elsevier, 1992-10-02)
The hippocampus appears to be involved in tonic regulation of the hypothalamo-pituitary-adrenocortical axis via interactions with corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP)-containing neurons of ...
Regulation of striatonigral prodynorphin peptides by dopaminergic agents
(Elsevier, 1990-06-04)
The primary purpose of this study was to examine the regulation of prodynorphin peptides by dopaminergic agents in the central nervous system. The indirectly acting catecholamine agonist -amphetamine sulfate (AMPH) and the ...