Now showing items 41-50 of 74
MSG effects on beta-endorphin and alpha-MSH in the hypothalamus and caudal medulla
(Elsevier, 1988)
Monosodium glutamate (MSG) was given to neonatal male rats to determine its effects on neurons containing beta-endorphin ([beta]-END) and alpha-melanocyte stimulating hormone ([alpha]-MSH) within the basal hypothalamus ...
Effects of fluoxetine on weight gain and food intake in smokers who reduce nicotine intake
(Elsevier, 1991)
The effect of fluoxetine hydrochloride, a 5-HT uptake inhibitor (60 mg/day PO), in preventing weight gain associated with nicotine reduction was investigated in participants in a double-blind, placebo-controlled smoking-cessation ...
Anatomical and biochemical studies of the opioid peptides and related substances in the brain
(Elsevier, 1980)
It is now clear that there are at least four opioid peptide-neuronal systems in mammalian brain: the enkephalins, beta-endorphin and dynorphin. The focus of this presentation will be twofold--to focus on the multiple ...
Cloning and expression of the A 2a adenosine receptor from guinea pig brain
(Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media, 1994-05)
A full-length complementary DNA (cDNA) clone encoding the guinea pig brain A 2 adenosine receptor has been isolated by polymerase chain reaction (PCR) and low-stringency-hybridization screening of a guinea pig brain cDNA ...
Summary of a National Institute of Mental Health workshop: developing animal models of anxiety disorders
(Springer-Verlag, 2001-10)
Rationale: There exists a wide range of animal models and measures designed to assess anxiety or fearfulness. However, the relationship between these models and clinical anxiety symptoms and syndromes is unclear. The ...
Combined autoradiographic-immunocytochemical analysis of opioid receptors and opioid peptide neuronal systems in brain
(Elsevier, 1985)
Using adjacent section autoradiography-immunocytochemistry, the distribution of [3H]naloxone binding sites was studied in relation to neuronal systems containing [Leu]enkephalin, dynorphin A, or [beta]-endorphin immunoreactivity ...
Changes in releasability of ACTH and Beta-endorphin with chronic stress
(Elsevier, 1985-02)
The activation of the hypothalamic pituitary adrenal axis by stress is well-known. Using inescapable intermittent footshock as a stressor in rats, we have previously demonstrated a rise in circulating plasma Beta-endorph ...
Acute effects of high-dose thyrotropin releasing hormone infusions in Alzheimer's disease
(Springer-Verlag, 1989-07)
Thyrotropin releasing hormone (TRH) was administered intravenously to ten patients with Alzheimer's Disease (AD) in a high-dose paradigm, thought to maximize central nervous system effects and potentially produce facilitation ...
TRH attenuates scopolamine-induced memory impairment in humans
(Springer-Verlag, 1990-03)
The brain tripeptide thyrotropin-releasing hormone (TRH) has been demonstrated to facilitate cholinergic neurotransmission. To test its interaction with the cholinergic system in humans, high-dose TRH (0.5 mg/kg) or placebo ...
Characterization of pro-opiomelanocortin processing in heterologous neuronal cells that express PC2 mRNA
(Elsevier, 1993-05)
We have investigated processing of monkey pro-opiomelanocortin (POMC) following transfection into heterologous neuronal Neuro 2A (N2A) cells. In several separately transfected stable cell lines (termed N2A/POMC2-like; N = ...