Now showing items 21-30 of 51
Nicotine may relieve symptoms of Parkinson's disease
(Springer-Verlag, 1994-09)
Two elderly patients with Parkinson's disease were treated with nicotine gum and patch. Reliable changes in symptomatology were noted, using a single-subject, placebo-control reversal design. Improvement was associated ...
Mecamylamine pretreatment increases subsequent nicotine self-administration as indicated by changes in plasma nicotine level
(Springer-Verlag, 1987-09)
Acute administration of mecamylamine, a centrally active nicotinic cholinergic agonist, has been shown to increase amount of smoking as indicated by smoking topography (e.g., puff rate, puff duration), expired carbon ...
Distribution of D2 dopamine receptor mRNA in the primate brain
(Elsevier, 1991)
1. The distribution of the messenger RNA (mRNA) encoding the D2dopamine receptor has been mapped in the monkey brain by hybridization.2. Using [35s]-labelled riboprobes corresponding to the region of the D2 dopamine ...
Comparison of acute and chronic lithium treatment on 3 H-norepinephrine uptake by rat brain slices
(Springer-Verlag, 1980-01)
The effects of lithium chloride, given IP in high (2.5–15 mEq/kg) and low (1.25 mEq/kg) doses twice daily, upon 3 H-norepinephrine uptake and retention were examined with slices from four regions of the rat brain, namely ...
Analysis of opioid and non-opioid end products of pro-dynorphin in the substantia nigra of the rat
(Elsevier, 1985-02)
The substantia nigra is among the richest pro-dynorphin terminal field regions in the rat brain. We therefore contrasted processing in this area to the known processing in the posterior pituitary. Fractionation of acid ...
In Vitro release of hypothalamic [beta]-endorphin [beta]E by arginine vasopressin, corticotropin-releasing hormone and 5-hydroxytryptamine: Evidence for release of opioid active and inactive [beta]E forms
(Elsevier, 1990-05)
The aims of the present experiments were: 1) to test whether substances which modulate beta-endorphin-immunoreactive [beta]E-ir release from the pituitary gland might act similarly in hypothalamic tissue; and 2) to further ...
In situ hybridization histochemistry with synthetic oligonucleotides: Strategies and methods
(Elsevier, 1985)
In situ hybridization histochemistry is a useful method for localizing specific mRNA and studying the regulation of gene expression in an anatomical context. Previously, classical recombinant DNA and microbiological ...
Adverse effects associated with the short-term treatment of panic disorder with imipramine, alprazolam or placebo
(Elsevier, 1994-03)
Side effects play a significant role in the selection of drugs to be used in panic disorder/agoraphobia whose polyphobic symptomatology often includes a suspiciousness about taking drugs and a fear of undesired side effects ...
MSG effects on beta-endorphin and alpha-MSH in the hypothalamus and caudal medulla
(Elsevier, 1988)
Monosodium glutamate (MSG) was given to neonatal male rats to determine its effects on neurons containing beta-endorphin ([beta]-END) and alpha-melanocyte stimulating hormone ([alpha]-MSH) within the basal hypothalamus ...
Anatomical and biochemical studies of the opioid peptides and related substances in the brain
(Elsevier, 1980)
It is now clear that there are at least four opioid peptide-neuronal systems in mammalian brain: the enkephalins, beta-endorphin and dynorphin. The focus of this presentation will be twofold--to focus on the multiple ...