Now showing items 1-10 of 94
The presence of two [alpha]-MSH positive cell groups in rat hypothalamus
(Elsevier, 1979-09-01)
Postnatal ontogeny of acetylated and non-acetylated B-endorphin in rat pituitary
(Elsevier, 1983)
Extracts of the anterior lobe and intermediate lobe of postnatal (P) (Day P1, P7, P14, P21, P28, P35, P42) and adult male Spraque-Dawley rats were analyzed by both a Beta-endorphin (B-END) radioimmunoassay and a radioimmunoassay ...
The effects of footshock stress on regional brain dopamine metabolism and pituitary [beta]-endorphin release in rats previously sensitized to amphetamine
(Elsevier, 1987-07)
The repeated intermittent administration of amphetamine (AMP) produces an enduring enhancement in the response of dopamine (DA) systems in the brain to a subsequent "challenge" with amphetamine. However, former amphetamine ...
Effects of morphine treatment on pro-opiomelanocortin systems in rat brain
(Elsevier, 1990-06-11)
In previous studies to determine whether chronic opiate administration might negatively feedback upon endogenous opioid systems in the CNS, investigators found no changes in steady-state concentrations of opioid peptides ...
Immunocytochemical localization of pro-opiomelanocortin-derived peptides in the adult rat spinal cord
(Elsevier, 1986-07-16)
A dispersed descending pro-opiomelanocortin (POMC) fiber system has been demonstrated by peroxidase-antiperoxidase (PAP) immunocytochemistry in the adult rat spinal cord. [beta]-endorphin, adrenocorticotrophic hormone ...
Enkephalinase: Selective inhibitors and partial characterization
(Elsevier, 1980)
There are at least two types of enzymes in brain, endopeptidases and aminopeptidases, which metabolize enkephalins. Evidence is presented to suggest that enkephalinase, an endopeptidase cleaving at the Gly-Phe bond, is ...
The NMDA receptor antagonist MK-801 increases morphine catalepsy and lethality
(Elsevier, 1991-03)
Interactions between excitatory amino acids and opioids were examined by studying the ability of the noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist MK-801 to affect morphine catalepsy and lethality. MK-801 ...
A sensitive coupled HPLC/RIA technique for separation of endorphins: Multiple forms of B-endorphin in rat pituitary intermediate vs. anterior lobe
(Elsevier, 1981-08)
A technique is described which couples High Performance Liquid Chromatography (HPLC) to radioimmuno assays (RIA), thus achieving high sensitivity with good specificity. This method allows the separation and detection of ...
Proopiomelanocortin peptide immunocytochemistry in rhesus monkey brain
(Elsevier, 1984-12)
The immunocytochemical distribution of Proopiomelanocortin (POMC) peptides ([beta]-endorphin, ACTH, [alpha]-MSH, 16K fragment) was studied in the brain of the rhesus monkey (Macaca mulatta). Some animals were administered ...