Now showing items 1-7 of 7
Degradation of [3H][beta]-endorphin in rat plasma is increased with chronic stress
(Elsevier, 1989-08-22)
With a number of acute stressors [beta]-endorphin is released into plasma. It is unclear if [beta]-endorphin is converted into any other biologically active products, nor it is clear if the rate or pathways of degradation ...
Induction of analgesia by central administration of ORG 2766, an analog of ACTH4-9
(Elsevier, 1981-01-05)
Dose-dependent analgesia was produced by microinjection of ORG 2766 into the periaqueductal gray (PAG). This analgesia was found to be potent and long-lasting and occurred at doses which were equimolar to those necessary ...
Binding of 3H-[beta]-endorphin to rat brain membranes: Characterization of opiate properties and interaction with ACTH
(Elsevier, 1980-05-30)
The binding of tritiated [beta]-endorphin (3H-[beta]-EP) to brain homogenates is described. This had been difficult to achieve due to the lack of availability of 3H-[beta]-EP and to technical difficulties associated with ...
[3H]dynorphin a binding and [kappa] selectivity of prodynorphin peptides in rat, guinea-pig and monkey brain
(Elsevier, 1986-03-04)
We have previously demonstrated that [3H]dynorphin A selectively labels [kappa] opioid receptors in guinea-pig whole brain. In these current studies, using protection from inactivation by [beta]-chloronaltrexamine ([beta]-CNA), ...