Now showing items 1-5 of 5
[beta]-Endorphin processing and cellular origins in rat spinal cord
(Elsevier, 1992-11)
While enkephalin and dynorphin peptides have been well characterized in the spinal cord, the cellular localization of [beta]-endorphin ([beta]E) and the processing of pro-opiomelanocortin (POMC) to [beta]E and other ...
A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques
(Elsevier, 1992-02)
D1, a subtype of the dopamine receptors, is widely distributed in the nervous system and has been shown to be positively coupled to adenylate cyclase. Using a combination of in vitro receptor autoradiographic and in situ ...
Site-directed mutagenesis of the human dopamine D2 receptor
(Elsevier, 1992-10-01)
Based on amino acid sequence and computer modeling, two conflicting three-dimensional models of the dopamine D2 receptor have been proposed. One model (Dahl et al., 1991, Proc. Natl. Acad. Sci. USA 88, 8111) suggests that ...
Evidence that [beta]-endorphin is synthesized in cells in the nucleus tractus solitarius: detection of POMC mRNA
(Elsevier, 1992-08-07)
Evidence from a number of sources indicates that the major site of pro-opiomelanocortin (POMC)-producing cells in the CNS is the arcuate nucleus of the hypothalamus. Using immunocytochemical techniques, a second, smaller ...
Selective forebrain fiber tract lesions implicate ventral hippocampal structures in tonic regulation of paraventricular nucleus corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) mRNA expression
(Elsevier, 1992-10-02)
The hippocampus appears to be involved in tonic regulation of the hypothalamo-pituitary-adrenocortical axis via interactions with corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP)-containing neurons of ...