Now showing items 1-3 of 3
Dynorphin is located throughout the CNS and is often co-localized with alpha-neo-endorphin
(Elsevier, 2006-04-07)
The opioid peptide dynorphin has been described as widely distributed in CNS when measured by RIA. Our previous immunohistochemical studies have only demonstrated dynorphin cells as those containing AVP. We now report the ...
Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects
(Elsevier, 2006-04-07)
Dynorphin and an opiate-inactive fragment des-Tyr-dynorphin produced similar effects on EEG, motor function and hippocampal unit firing. Naloxone had no effect on the actions of dynorphin in these systems and dynorphin ...
The signal peptide of pro-opiomelancortin: Validation of a specific radioimmunoassay
(Elsevier, 2006-04-07)
The N-terminus portion of the POMC leader sequence (signal peptide) was synthesized, and an antiserum was raised against it. A radioimmunoassay was developed which is effective at a dilution of 1:500,000, and sensitive at ...