Now showing items 1-10 of 11
Peptide F (pro-enkephalin fragment) : Radioimmunoassay, and stress-induced changes in adrenal
(Elsevier, 2006-04-07)
Utilizing a nine amino-acid (Asp-Glu-Leu-Tyr-Pro-Leu-Glu-Val-Glu) non-enkephalin containing fragment of Peptide F from the pro-enkephalin molecule, a radioimmunoassay was developed. Extraction of bovine, rat, and guinea ...
Plasma beta-endorphin-like immunoreactivity, self reported pain perception and anxiety levels in women during pregnancy and labor
(Elsevier, 2006-04-07)
Plasma Beta-endorphin (B-END) immunoreactivity was measured in 19 men, 16 women at midcycle, and ten pregnant women at various points in their pregnancies. There is a significant difference between the levels measured in ...
Pulse-chase studies of the POMC/Beta-endorphin system in the pituitary of acutely and chronically stressed rats
(Elsevier, 2006-04-07)
Experiments were carried out to determine whether stress induces biochemical changes in the pro-opiomelanocortin (POMC) system in anterior (AL) and intermediate-posterior lobe (IPL) of rat. In a series of pulse-chase ...
Dynorphin is located throughout the CNS and is often co-localized with alpha-neo-endorphin
(Elsevier, 2006-04-07)
The opioid peptide dynorphin has been described as widely distributed in CNS when measured by RIA. Our previous immunohistochemical studies have only demonstrated dynorphin cells as those containing AVP. We now report the ...
Colocalization of estrogen β-receptor messenger RNA with orphanin FQ, vasopressin and oxytocin in the rat hypothalamic paraventricular and supraoptic nuclei
(Springer-Verlag, 2003-05)
The functional significance of the novel estrogen receptor β in brain areas that exclusively contain the ERβ receptor subtype such as the paraventricular (PVN) and the supraoptic (SON) nuclei of the hypothalamus is not yet ...
Dynorphin (1-17): Lack of analgesia but evidence for non-opiate electrophysiological and motor effects
(Elsevier, 2006-04-07)
Dynorphin and an opiate-inactive fragment des-Tyr-dynorphin produced similar effects on EEG, motor function and hippocampal unit firing. Naloxone had no effect on the actions of dynorphin in these systems and dynorphin ...
Selective Breeding for Divergence in Novelty-seeking Traits: Heritability and Enrichment in Spontaneous Anxiety-related Behaviors
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2006-02-24)
Outbred Sprague–Dawley rats can be classified as high responders (HR) or low responders (LR) based on their levels of exploratory locomotion in a novel environment. While this novelty-seeking dimension was originally related ...
Social defeat alters the acquisition of cocaine self-administration in rats: role of individual differences in cocaine-taking behavior
(Springer-Verlag, 2001-12)
Rationale : It is known that social defeat can modulate cocaine self-administration. However, it is unclear whether this psychosocial stressor affects drug-taking behavior to the same extent across all individual animals, ...
Plasma measures of B-endorphin-like immunoreactivity in depressives and other psychiatric subjects
(Elsevier, 2006-04-07)
We report the utilization of a very sensitive radioimmunoassay for plasma B-END, which has enabled us to examine the suppressibility of B-END-like material, under dexamethasone challenge, on a population of depressed ...
The signal peptide of pro-opiomelancortin: Validation of a specific radioimmunoassay
(Elsevier, 2006-04-07)
The N-terminus portion of the POMC leader sequence (signal peptide) was synthesized, and an antiserum was raised against it. A radioimmunoassay was developed which is effective at a dilution of 1:500,000, and sensitive at ...