Investigation and validation of intersite fMRI studies using the same imaging hardware
dc.contributor.author | Sutton, Bradley P. | en_US |
dc.contributor.author | Goh, Joshua | en_US |
dc.contributor.author | Hebrank, Andrew | en_US |
dc.contributor.author | Welsh, Robert C. | en_US |
dc.contributor.author | Chee, Michael W. L. | en_US |
dc.contributor.author | Park, Denise C. | en_US |
dc.date.accessioned | 2008-08-04T15:13:34Z | |
dc.date.available | 2009-07-06T16:34:52Z | en_US |
dc.date.issued | 2008-07 | en_US |
dc.identifier.citation | Sutton, Bradley P.; Goh, Joshua; Hebrank, Andrew; Welsh, Robert C.; Chee, Michael W.L.; Park, Denise C. (2008). "Investigation and validation of intersite fMRI studies using the same imaging hardware." Journal of Magnetic Resonance Imaging 28(1): 21-28. <http://hdl.handle.net/2027.42/60451> | en_US |
dc.identifier.issn | 1053-1807 | en_US |
dc.identifier.issn | 1522-2586 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/60451 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=18581342&dopt=citation | en_US |
dc.description.abstract | Purpose To provide a between-site comparison of functional MRI (fMRI) signal reproducibility in two laboratories equipped with identical imaging hardware and software. Many studies have looked at within-subject reliability and more recent efforts have begun to calibrate responses across sites, magnetic field strengths, and software. By comparing identical imaging hardware and software, we provide a benchmark for future multisite comparisons. Materials and Methods We evaluated system compatibility based on noise and stability properties of phantom scans and contrast estimates from repeated runs of a blocked motor and visual task on the same four subjects at both sites. Results Analysis of variance (ANOVA) and region of interest (ROI) analysis confirmed that site did not play a significant role in explaining variance in our large fMRI dataset. Effect size analysis shows that between-subject differences account for nearly 10 times more variance than site effects. Conclusion We show that quantitative comparisons of contrast estimates derived from cognitive experiments can reliably be compared across two sites. This allows us to establish an effective platform for comparing group differences between two sites using fMRI when group effects are potentially confounded with site, as in the study of neurocultural differences between countries or multicenter clinical trials. J. Magn. Reson. Imaging 2008;28:21–28. © 2008 Wiley-Liss, Inc. | en_US |
dc.format.extent | 1893834 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Imaging | en_US |
dc.title | Investigation and validation of intersite fMRI studies using the same imaging hardware | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Radiology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationother | Bioengineering Department, University of Illinois at Urbana-Champaign, Urbana, Illinois ; Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois ; Bioengineering, 3120 DCL, 1304 W. Springfield Ave., Urbana, IL 61801 | en_US |
dc.contributor.affiliationother | Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois ; Department of Psychology, University of Illinois at Urbana-Champaign, Urbana, Illinois ; Cognitive Neuroscience Laboratory, Duke-NUS Graduate Medical School, Singapore | en_US |
dc.contributor.affiliationother | Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois ; Center for Brain Health, University of Texas at Dallas, Dallas, Texas | en_US |
dc.contributor.affiliationother | Cognitive Neuroscience Laboratory, Duke-NUS Graduate Medical School, Singapore | en_US |
dc.contributor.affiliationother | Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois ; Department of Psychology, University of Illinois at Urbana-Champaign, Urbana, Illinois ; Center for Brain Health, University of Texas at Dallas, Dallas, Texas | en_US |
dc.identifier.pmid | 18581342 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/60451/1/21419_ftp.pdf | |
dc.identifier.doi | http://dx.doi.org/10.1002/jmri.21419 | en_US |
dc.identifier.source | Journal of Magnetic Resonance Imaging | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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