Now showing items 1-9 of 9
Macrophage infiltration in human non-small-cell lung cancer: the role of CC chemokines
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 2000-04)
Bronchogenic carcinoma is the leading cause of malignancy-related mortality in the United States, with an overall 5-year survival rate of less than 15%. This aggressive behavior reflects, among other traits, the capacity ...
The murine CC chemokine, 6C-kine, inhibits tumor growth and angiogenesis in a human lung cancer SCID mouse model
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 2001-01)
The recently described CC chemokine, 6C-kine, is unique in that it contains -six rather than the usual four conserved cysteines typical of this family. Furthermore, murine 6C-kine binds to one of the CXC chemokine receptors ...
An improved method for immobilizing IgG antibodies on protein A-agarose
(Elsevier, 1990-03-09)
This report describes a modification of a procedure developed by others for crosslinking IgG to protein A which itself is covalently linked to a gel support. Earlier immunoaffinity columns were described as having large ...
Calcitriol-mediated modulation of urokinase-type plasminogen activator and plasminogen activator inhibitor-2
(Elsevier, 1991-02-15)
Calcitriol-induced differentiation of U937 mononuclear phagocytes is known to have divergent effects on the synthesis of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor-2 (PAI-2). In this ...
The oral gold compound auranofin triggers arachidonate release and cyclooxygenase metabolism in the alveolar macrophage
(Elsevier, 1988-12)
We examined the effect of in vitro incubation with the oral gold compound auranofin (AF) on arachidonic acid (AA) release and metabolism by rat alveolar macrophages (AMs). AF stimulated dose- and time-dependent release of ...
Inhibition of alveolar macrophage 5-lipoxygenase metabolism by auranofin
(Elsevier, 1989-05-15)
We have examined the effect of the oral gold compound auranofin (AF) on calcium ionophore A23187-induced arachidonic acid metabolism in the rat alveolar macrophage. Both reverse-phase high performance liquid Chromatographie ...
Reduced 5-lipoxygenase metabolism of arachidonic acid in macrophages rrom 1,25-dihydroxyvitamin D3-deficient rats
(Elsevier, 1994-11)
The peripheral blood monocyte (PBM) migrates into tissues and differentiates into mature tissue macrophages. Previous investigations from our laboratory have demonstrated that PBM have reduced 5-lipoxygenase (5-LO) metabolism ...
Semi-quantitative ventilation/perfusion scintigraphy and single-photon emission tomography for evaluation of lung volume reduction surgery candidates: description and prediction of clinical outcome
(Springer-Verlag; Springer-Verlag Berlin Heidelberg, 1999-06)
Ventilation/perfusion scans with single-photon emission tomography (SPET) were reviewed to determine their usefulness in the evaluation of lung volume reduction surgery (LVRS) candidates, and as a predictor of outcome after ...
TLR9 activation is a key event for the maintenance of a mycobacterial antigen-elicited pulmonary granulomatous response
(WILEY-VCH Verlag, 2007-10)
Type 1 (Th1) granulomas can be studied in mice sensitized with mycobacterium antigens followed by challenge of agarose beads covalently coupled to purified protein derivative. TLR9 is known to play a role in the regulation ...