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Low Allele Frequency of MLH1 D132H in American Colorectal and Endometrial Cancer Patients
(Springer-Verlag; The American Society of Colon and Rectal Surgeons, 2005-09)
Hereditary nonpolyposis colon cancer is caused by mutations in DNA mismatch repair genes, predominantly MLH1 and MSH2 . Classic MLH1 mutations cause an approximately 20-fold increase in colorectal cancer susceptibility. ...