View Item 

Show simple item record

Helical Hairpin Structure of a Potent Antimicrobial Peptide MSI-594 in Lipopolysaccharide Micelles by NMR Spectroscopy
dc.contributor.authorBhunia, Anirbanen_US
dc.contributor.authorRamamoorthy, Ayyalusamyen_US
dc.date.accessioned2009-03-03T20:08:21Z
dc.date.available2010-04-14T17:40:05Zen_US
dc.date.issued2009-02-16en_US
dc.identifier.citationBhunia, Anirban; Ramamoorthy, Ayyalusamy; Bhattacharjya, Surajit (2009). "Helical Hairpin Structure of a Potent Antimicrobial Peptide MSI-594 in Lipopolysaccharide Micelles by NMR Spectroscopy." Chemistry - A European Journal 15(9): 2036-2040. <http://hdl.handle.net/2027.42/61865>en_US
dc.identifier.issn0947-6539en_US
dc.identifier.issn1521-3765en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/61865
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=19180607&dopt=citationen_US
dc.description.abstractEssential understanding : Elucidation of structural requirements and interactions of antimicrobial peptides with lipopolysaccharide (LPS) are essential to understand the mechanism of action of antimicrobial peptides. The highly active antimicrobial peptide MSI-594 (see figure for electrostatic potential surface) acquires a novel helical hairpin structure in complex with LPS. The structure and interactions of MSI-594 with LPS presented here provide important insights into the mechanism of outer membrane permeabilization by antimicrobial peptides.en_US
dc.format.extent1918814 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherWILEY-VCH Verlagen_US
dc.subject.otherChemistryen_US
dc.subject.otherGeneral Chemistryen_US
dc.titleHelical Hairpin Structure of a Potent Antimicrobial Peptide MSI-594 in Lipopolysaccharide Micelles by NMR Spectroscopyen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Chemistry and Biophysics, University of Michigan, Ann Arbor, MI 48109-1055 (USA), Fax: (+1) 734-763-2307en_US
dc.contributor.affiliationotherSchool of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Fax: (+65) 6791-3856en_US
dc.identifier.pmid19180607en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/61865/1/chem_200802635_sm_miscellaneous_information.pdf
dc.identifier.doi10.1002/chem.200802635en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
chem_200802635_sm_miscellaneou ...
Size:
1.829MB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.