Prevalence, timing, and predictors of transitions from inhalant use to Inhalant Use Disorders
dc.contributor.author | Perron, Brian | |
dc.contributor.author | Howard, Matthew O. | |
dc.contributor.author | Maitra, Samopriyo | |
dc.contributor.author | Vaughn, Michael G. | |
dc.date.accessioned | 2009-03-05T14:56:32Z | |
dc.date.available | 2009-03-05T14:56:32Z | |
dc.date.issued | 2009-03-01 | |
dc.identifier.citation | Drug and Alcohol Dependence, Vol. 100, No. 3, 2009, pp. 277-284 <http://hdl.handle.net/2027.42/61908> | en |
dc.identifier.uri | https://hdl.handle.net/2027.42/61908 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=19091490&dopt=citation | |
dc.description.abstract | BACKGROUND: Few studies of the natural history of DSM-IV inhalant substance use disorders (I-SUDs) have been conducted. This investigation examined the prevalence, timing, and predictors of transitions from inhalant use to formal I-SUDs among inhalant users within a nationally representative sample. METHODS: Participants were 664 U.S. residents participating in the 2000-2001 National Epidemiologic Survey on Alcohol and Related Conditions who reported lifetime inhalant use. Respondents completed structured interviews assessing DSM-IV psychiatric/substance use disorders. Bivariate and Cox regression analyses were conducted to identify risk factors for transitions from inhalant use to I-SUDs. RESULTS: Nearly one in five (19.4%) persons initiating inhalant use developed an I-SUD. Most I-SUD transitions were to inhalant abuse rather than inhalant dependence. Risk for development of I-SUDs was greatest in the first year following initiation of inhalant use and low thereafter. Multivariate proportional hazards models indicated that presence of a mood/anxiety disorder (HR=7.7, CI=3.1-18.9) or alcohol use disorder (HR=11.9, CI=5.46-26.00) antedating initiation of inhalant use predicted significantly elevated risk for I-SUDs, whereas being married conferred a lower risk for onset of I-SUDs. CONCLUSIONS: I-SUDs were relatively common among inhalant users, generally occurred in the year following initiation of inhalant use, and were associated with early-onset mood/anxiety and alcohol use disorders. Given the young average age at onset of inhalant use and the rapidity with which most I-SUDs developed, interventions directed to adolescents who have initiated inhalant use might be effective in reducing the proportion of inhalant users who develop I-SUDs. | en |
dc.format.extent | 390451 bytes | |
dc.format.mimetype | application/pdf | |
dc.language.iso | en_US | en |
dc.publisher | Elsevier | en |
dc.subject | Inhalants | en |
dc.subject | Inhalant Use Disorders | en |
dc.subject | NESARC | en |
dc.subject | Volatile Solvents | en |
dc.title | Prevalence, timing, and predictors of transitions from inhalant use to Inhalant Use Disorders | en |
dc.type | Article | en |
dc.subject.hlbsecondlevel | Social Work | |
dc.subject.hlbtoplevel | Social Sciences | |
dc.description.peerreviewed | Peer Reviewed | en |
dc.contributor.affiliationum | Brian Perron | en |
dc.contributor.affiliationumcampus | Ann Arbor | en |
dc.identifier.pmid | 19091490 | |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/61908/1/Transition.pdf | |
dc.identifier.doi | 10.1016/j.drugalcdep.2008.10.017 | |
dc.identifier.source | Drug and Alcohol Dependence | en_US |
dc.owningcollname | Social Work, School of (SSW) |
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