Advanced squamous cell carcinoma of the oropharynx: Efficacy of positron emission tomography and computed tomography for determining primary tumor response during induction chemotherapy
dc.contributor.author | Chepeha, Douglas B. | en_US |
dc.contributor.author | Sacco, Assuntina G. | en_US |
dc.contributor.author | Oxford, Lance E. | en_US |
dc.contributor.author | Karamchandani, Rahul | en_US |
dc.contributor.author | Miller, Tamara H. | en_US |
dc.contributor.author | Teknos, Theodoros N. | en_US |
dc.contributor.author | Bradford, Carol R. | en_US |
dc.contributor.author | Eisbruch, Avraham | en_US |
dc.contributor.author | Worden, Frank M. | en_US |
dc.contributor.author | Urba, Susan G. | en_US |
dc.contributor.author | Mukherji, Suresh K. | en_US |
dc.contributor.author | Bui, Chuong | en_US |
dc.contributor.author | Frey, Kirk A. | en_US |
dc.contributor.author | Wolf, Gregory T. | en_US |
dc.contributor.author | Lee, Julia S. | en_US |
dc.date.accessioned | 2009-04-09T14:42:40Z | |
dc.date.available | 2010-06-02T14:34:29Z | en_US |
dc.date.issued | 2009-04 | en_US |
dc.identifier.citation | Chepeha, Douglas B.; Sacco, Assuntina G.; Oxford, Lance E; Karamchandani, Rahul; Miller, Tamara H.; Teknos, Theodoros N.; Bradford, Carol R.; Eisbruch, Avraham; Worden, Frank M.; Urba, Susan G.; Mukherji, Suresh K.; Bui, Chuong; Frey, Kirk A.; Wolf, Gregory T.; Lee, Julia S. (2009). "Advanced squamous cell carcinoma of the oropharynx: Efficacy of positron emission tomography and computed tomography for determining primary tumor response during induction chemotherapy." Head & Neck 31(4): 452-460. <http://hdl.handle.net/2027.42/62055> | en_US |
dc.identifier.issn | 1043-3074 | en_US |
dc.identifier.issn | 1097-0347 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/62055 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=19189338&dopt=citation | en_US |
dc.description.abstract | Background To evaluate the efficacy of fluorine-18-fluorodeoxyglucose emission tomography (FDG-PET) and CT versus endoscopy with biopsy under general anesthesia for estimating tumor volume reduction among patients treated with induction chemotherapy for advanced squamous cell carcinoma (SCC) of the oropharynx. Methods Twelve patients with oropharyngeal SCC nested in a phase II, induction chemoradiation, organ preservation trial (University of Michigan Cancer Center 9921) underwent tumor volume reduction estimation as assessed by FDG-PET, CT, and endoscopy with biopsy. Results In 9 of 12 patients, FDG-PET, CT, and endoscopy demonstrated agreement in estimation of tumor reduction. Two patients had discordant results, whereas 1 patient was inadequately evaluated with FDG-PET. The kappa value for PET versus endoscopy was 0.62, which is categorized as substantial agreement. The kappa value for CT versus endoscopy was 0.40, which is categorized as fair agreement. Conclusion FDG-PET may be as efficacious as endoscopy with biopsy under general anesthesia for estimating tumor volume reduction with induction chemotherapy. © 2009 Wiley Periodicals, Inc. Head Neck, 2009 | en_US |
dc.format.extent | 133020 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cancer Research, Oncology and Pathology | en_US |
dc.title | Advanced squamous cell carcinoma of the oropharynx: Efficacy of positron emission tomography and computed tomography for determining primary tumor response during induction chemotherapy | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Otolaryngology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Otolaryngology–Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan 48109-0312 ; Department of Otolaryngology–Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan 48109-0312 | en_US |
dc.contributor.affiliationum | Department of Otolaryngology–Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan 48109-0312 | en_US |
dc.contributor.affiliationum | Department of Otolaryngology–Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan 48109-0312 | en_US |
dc.contributor.affiliationum | Department of Otolaryngology–Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan 48109-0312 | en_US |
dc.contributor.affiliationum | Department of Otolaryngology–Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan 48109-0312 | en_US |
dc.contributor.affiliationum | Department of Otolaryngology–Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan 48109-0312 | en_US |
dc.contributor.affiliationum | Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Internal Medicine–Hematology/Oncology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Internal Medicine–Hematology/Oncology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Radiology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Radiology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Otolaryngology–Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan 48109-0312 | en_US |
dc.contributor.affiliationother | Department of Otolaryngology–Head and Neck Surgery, Baylor University Medical Center, Dallas, Texas | en_US |
dc.contributor.affiliationother | Department of Nuclear Medicine, Nepean Hospital, Penrith NSW, Sydney, Australia | en_US |
dc.contributor.affiliationother | Cancer Center, Univeristy of Michigan, Ann Arbor, Michigan | en_US |
dc.identifier.pmid | 19189338 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/62055/1/21006_ftp.pdf | |
dc.identifier.doi | 10.1002/hed.21006 | en_US |
dc.identifier.source | Head & Neck | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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