Pediatric duodenal cancer and biallelic mismatch repair gene mutations
dc.contributor.author | Roy, Sumita | en_US |
dc.contributor.author | Raskin, Leon | en_US |
dc.contributor.author | Raymond, Victoria M. | en_US |
dc.contributor.author | Thibodeau, Stephen N. | en_US |
dc.contributor.author | Mody, Rajen J. | en_US |
dc.contributor.author | Gruber, Stephen B. | en_US |
dc.date.accessioned | 2009-06-01T19:17:02Z | |
dc.date.available | 2010-08-02T17:56:56Z | en_US |
dc.date.issued | 2009-07-15 | en_US |
dc.identifier.citation | Roy, Sumita; Raskin, Leon; Raymond, Victoria M.; Thibodeau, Stephen N.; Mody, Rajen J.; Gruber, Stephen B. (2009). "Pediatric duodenal cancer and biallelic mismatch repair gene mutations." Pediatric Blood & Cancer 53(1): 116-120. <http://hdl.handle.net/2027.42/62997> | en_US |
dc.identifier.issn | 1545-5009 | en_US |
dc.identifier.issn | 1545-5017 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/62997 | |
dc.description.abstract | Gastrointestinal malignancies are extremely rare in the pediatric population, and duodenal cancers represent an even more unusual entity. Intestinal cancers in young adults and children have been observed to be associated with functional deficiencies of the mismatch repair (MMR) system causing a cancer-predisposition syndrome. We report the case of a 16-year-old female with duodenal adenocarcinoma and past history of medulloblastoma found to have a novel germline bialleleic truncating mutation (c.[949C>T]+[949C>T]) of the PMS2 gene. Pediatr Blood Cancer 2009;53:116–120. © 2009 Wiley-Liss, Inc. | en_US |
dc.format.extent | 144604 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cancer Research, Oncology and Pathology | en_US |
dc.title | Pediatric duodenal cancer and biallelic mismatch repair gene mutations | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pediatrics | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Pediatric Hematology-Oncology, Dept. of Pediatrics, University of Michigan Health System, Ann Arbor, Michigan ; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Health System, 1500 East Medical Center Drive, L2110 Women's Hospital, Ann Arbor, MI 48109-0238. | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Division of Pediatric Hematology-Oncology, Dept. of Pediatrics, University of Michigan Health System, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan ; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan ; Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan ; Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of Michigan Health System, 1500 East Medical Center Drive, L2110 Women's Hospital, Ann Arbor, MI 48109-0238. | en_US |
dc.contributor.affiliationother | Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota | en_US |
dc.identifier.pmid | 19283792 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/62997/1/21957_ftp.pdf | |
dc.identifier.doi | 10.1002/pbc.21957 | en_US |
dc.identifier.source | Pediatric Blood & Cancer | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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