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Gene Transfer In Vivo with DNA–Liposome Complexes: Lack of Autoimmunity and Gonadal Localization

dc.contributor.authorNabel, Elizabeth G.en_US
dc.contributor.authorGordon, Daviden_US
dc.contributor.authorYang, Zhi-Yongen_US
dc.contributor.authorXu, Lingen_US
dc.contributor.authorSan, Hongen_US
dc.contributor.authorPlautz, Gregory E.en_US
dc.contributor.authorWu, Bei-Yueen_US
dc.contributor.authorGao, Xiangen_US
dc.contributor.authorHuang, Leafen_US
dc.contributor.authorNabel, Gary J.en_US
dc.date.accessioned2009-07-10T18:57:22Z
dc.date.available2009-07-10T18:57:22Z
dc.date.issued1992-12-01en_US
dc.identifier.citationNabel, Elizabeth G.; Gordon, David; Yang, Zhi-Yong; Xu, Ling; San, Hong; Plautz, Gregory E.; Wu, Bei-Yue; Gao, Xiang; Huang, Leaf; Nabel, Gary J. (1992). "Gene Transfer In Vivo with DNA–Liposome Complexes: Lack of Autoimmunity and Gonadal Localization." Human Gene Therapy 3(6): 649-656 <http://hdl.handle.net/2027.42/63110>en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/63110
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1482705&dopt=citationen_US
dc.description.abstractOverview summary The use of DNA–liposome complexes to transfer genes in vivo is now underway in an active clinical protocol. Mouse safety and acute toxicity data have been published previously (Hum. Gene Ther. 3, 267–275). In the present paper, Nabel et al. begin to provide long-term safety data, specifically with regard to the potential for autoimmune damage to major organs or for the transfer of the foreign genes into reproductive tissue.en_US
dc.format.extent342173 bytes
dc.format.extent2489 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherMary Ann Liebert, Inc., publishersen_US
dc.titleGene Transfer In Vivo with DNA–Liposome Complexes: Lack of Autoimmunity and Gonadal Localizationen_US
dc.typeArticleen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.identifier.pmid1482705en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/63110/1/hum.1992.3.6-649.pdf
dc.identifier.doidoi:10.1089/hum.1992.3.6-649en_US
dc.identifier.sourceHuman Gene Therapyen_US
dc.identifier.sourceHuman Gene Therapyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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