Antifungal prophylaxis in liver transplant recipients
dc.contributor.author | Eschenauer, Gregory A. | en_US |
dc.contributor.author | Lam, Simon W. | en_US |
dc.contributor.author | Carver, Peggy L. | en_US |
dc.date.accessioned | 2009-08-12T15:33:59Z | |
dc.date.available | 2010-10-05T18:27:29Z | en_US |
dc.date.issued | 2009-08 | en_US |
dc.identifier.citation | Eschenauer, Gregory A.; Lam, Simon W.; Carver, Peggy L. (2009). "Antifungal prophylaxis in liver transplant recipients." Liver Transplantation 15(8): 842-858. <http://hdl.handle.net/2027.42/63531> | en_US |
dc.identifier.issn | 1527-6465 | en_US |
dc.identifier.issn | 1527-6473 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/63531 | |
dc.description.abstract | Although the overall incidence of fungal infections in liver transplant recipients has declined, these infections still contribute significantly to the morbidity and mortality of patients with risk factors for infection. Although antifungal prophylaxis has been widely studied and practiced, no consensus exists on which patients should receive prophylaxis, with which agent, and for what duration. Numerous studies have attempted to ascertain independent risk factors for invasive fungal infections in liver transplant patients, and these data, in addition to clinical trials, identify several patient groups at exceedingly high risk of fungal infection. These include retransplant patients, patients with renal failure requiring hemodialysis or renal replacement therapy, and those requiring reoperations after transplant. Because the majority of infections occur in the first month after transplantation, prophylaxis should be continued for 4-6 weeks. However, local epidemiology and research should guide decisions regarding choice of agent as well as overall development of interinstitutional guidelines, because the incidence and spectrum of infection may differ dramatically among institutions. Liver Transpl 15:842–858, 2009. © 2009 AASLD. | en_US |
dc.format.extent | 176231 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Surgery | en_US |
dc.title | Antifungal prophylaxis in liver transplant recipients | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Surgery and Anesthesiology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | University of Michigan Health System, Ann Arbor, MI | en_US |
dc.contributor.affiliationother | University of Pittsburgh Medical Center, Pittsburgh, PA ; Telephone: 330-414-0563; FAX: 412-648-6399 ; Falk Medical Building, Suite 3A, 3601 Fifth Avenue, Pittsburg, PA 15213 | en_US |
dc.contributor.affiliationother | The Cleveland Clinic, Cleveland, OH | en_US |
dc.identifier.pmid | 19642130 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/63531/1/21826_ftp.pdf | |
dc.identifier.doi | 10.1002/lt.21826 | en_US |
dc.identifier.source | Liver Transplantation | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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