Bladder outlet obstruction in painful bladder syndrome/interstitial cystitis
dc.contributor.author | Cameron, Anne P. | en_US |
dc.contributor.author | Gajewski, Jerzy B. | en_US |
dc.date.accessioned | 2009-11-06T16:51:08Z | |
dc.date.available | 2010-03-01T21:10:29Z | en_US |
dc.date.issued | 2009-11 | en_US |
dc.identifier.citation | Cameron, Anne P.; Gajewski, Jerzy B. (2009). "Bladder outlet obstruction in painful bladder syndrome/interstitial cystitis Conflict of interest: none. Dirk De Ridder led the review process. ." Neurourology and Urodynamics 28(8): 944-948. <http://hdl.handle.net/2027.42/64338> | en_US |
dc.identifier.issn | 0733-2467 | en_US |
dc.identifier.issn | 1520-6777 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/64338 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=19301413&dopt=citation | en_US |
dc.description.abstract | Aims Obstructive symptoms such as slow stream, dribbling and straining are often reported by painful bladder syndrome and interstitial cystitis (PBS/IC) patients. Our hypothesis was that some patients with PBS/IC have an associated measurable bladder outlet obstruction (BOO) secondary to dysfunctional voiding and that those patients with more severe PBS/IC are more likely to have BOO. Methods This is a retrospective chart review of female patients diagnosed with PBS/IC based on the NIDDK research definition. Charts were reviewed for clinical symptom severity, ulcer or non-ulcer PBS/IC on cystoscopy, and pressure-flow urodynamics (UDPF). Patients were excluded if they had a urinary infection at the time of urodynamics or did not meet study entry requirements. The cut-off values of ≤12 ml/sec and ≥25 cm of water was used to define BOO. Results Of the 231 women: 38 had ulcer PBS/IC and 193 had non-ulcer PBS/IC. MCC was 269 ml in non-ulcer PBS/IC and 200 ml in ulcer PBS/IC ( P = 0.006). One hundred eleven women (48%) met criteria for obstruction. MCC was 298 ml in the non-obstructed group and 214 ml in the obstructed group ( P < 0.0001). The maximum flow with non-ulcer PBS/IC was 11.0 ml/sec and in ulcer PBS/IC 8.9 ml/sec ( P = 0.04) Detrusor pressure at maximum flow was 33.3 cm H 2 O, in non-ulcer, and 37.4 cm H 2 O in ulcer PBS/IC ( P = 0.01). Conclusions Forty-eight percent of our PBS/IC patients have BOO, and increasing severity of PBS/IC is associated with higher voiding pressure. Neurourol. Urodynam. 28:944–948, 2009. © 2009 Wiley-Liss, Inc. | en_US |
dc.format.extent | 138262 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Miscellaneous Medical | en_US |
dc.title | Bladder outlet obstruction in painful bladder syndrome/interstitial cystitis | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Urology, University of Michigan, Ann Arbor, Michigan ; 1500 E Medical Center Drive, 3875 Taubman Center, Ann Arbor, MI 48109. | en_US |
dc.contributor.affiliationother | Department of Urology, Dalhousie University, Halifax, Nova Scotia, Canada | en_US |
dc.identifier.pmid | 19301413 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/64338/1/20729_ftp.pdf | |
dc.identifier.doi | 10.1002/nau.20729 | en_US |
dc.identifier.source | Neurourology and Urodynamics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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