Now showing items 11-20 of 22
Distribution of co-activators CBP and p300 during mouse oocyte and embryo development
(Wiley Subscription Services, Inc., A Wiley Company, 2006-07)
cAMP response element binding protein (CREB)-binding protein (CBP) and p300 are two structurally related transcriptional co-activators that activate expression of many eukaryotic genes. Current dogma would suggest that ...
Wide excision without radiation for desmoplastic melanoma
(Wiley Subscription Services, Inc., A Wiley Company, 2005-10-01)
BACKGROUND Adjuvant radiation has been proposed for the treatment of patients with desmoplastic melanoma, who reportedly have local recurrence rates as high as 40–60%. The authors investigated local recurrence rates at a ...
Large Fetal Pulmonary Arteriovenous Fistula: Impact on Pulmonary Development
(Springer-Verlag; Springer-Verlag New York Inc., 2002-07)
A case report of a patient with a large pulmonary arteriovenous fistula and valvar pulmonary stenosis is presented. The fistula was diagnosed prenatally and its effect on in utero cardiovascular growth and development ...
Racial differences in cervical cancer survival in the Detroit metropolitan area
(Wiley Subscription Services, Inc., A Wiley Company, 2008-03-15)
BACKGROUND African-American (AA) women have lower survival rates from cervical cancer compared with white women. The objective of this study was to examine the influence of socioeconomic status (SES) and other variables ...
Desmoplastic and neurotropic melanoma
(Wiley Subscription Services, Inc., A Wiley Company, 2004-02-01)
BACKGROUND Desmoplastic and neurotropic melanoma (DNMM) occasionally metastasizes to regional lymph nodes and extranodal sites. The value of sentinel lymph node biopsy (SLNB) has not been demonstrated clearly for patients ...
State-Specific Trends in Preterm Delivery: Are Rates Really Declining Among Non-Hispanic African Americans Across the United States?
(Kluwer Academic Publishers-Plenum Publishers; Springer Science+Business Media, Inc., 2006-01)
Objectives : This study sought to examine state-specific trends in preterm delivery rates among non-Hispanic African Americans and to assess whether these rates are influenced by misclassification of gestational age. Methods ...
Thin primary cutaneous melanomas
(Wiley Subscription Services, Inc., A Wiley Company, 2002-10-01)
BACKGROUND Public awareness and education may lead to the detection of thinner melanomas, which may result in a decrease in morbidity and mortality rates. Which detection patterns, lesion, and patient characteristics are ...
Sentinel lymph node biopsy for patients with problematic spitzoid melanocytic lesions
(Wiley Subscription Services, Inc., A Wiley Company, 2003-01-15)
BACKGROUND Spindle and/or epithelioid melanocytic proliferations that display overlapping histopathologic features of Spitz nevus and Spitz-like melanoma are diagnostically difficult and controversial melanocytic tumors. ...
A Bayesian hierarchical approach to multirater correlated ROC analysis
(John Wiley & Sons, Ltd., 2005)
In a common ROC study design, several readers are asked to rate diagnostics of the same cases processed under different modalities. We describe a Bayesian hierarchical model that facilitates the analysis of this study ...
Specific inhibition of mouse oocyte nuclear protein phosphatase-1 stimulates germinal vesicle breakdown
(Wiley Subscription Services, Inc., A Wiley Company, 2003-05)
Okadaic acid (OA)-induced germinal vesicle breakdown (GVBD) and localization of protein phosphatase-1 (PP1) in oocyte nuclei are suggestive of PP1's role in regulating oocyte GVBD. To explore this possibility, we microinjected ...