Now showing items 1-7 of 7
Prenatal diagnosis of nonrhizomelic chondrodysplasiapunctata (Conradi-HÜnermann syndrome)
(Wiley Subscription Services, Inc., A Wiley Company, 1993-09-01)
Chondrodysplasia punctata has been classified into two major types including the rare autosomal recessive “rhizomelic type” and a more common but genetically heterogenous nonrhizomelic type (referrred to by some authors ...
Efficient tumour formation by single human melanoma cells
(Nature Publishing Group, 2008-12-04)
A fundamental question in cancer biology is whether cells with tumorigenic potential are common or rare within human cancers. Studies on diverse cancers, including melanoma, have indicated that only rare human cancer cells ...
Tissue-specific expression of the human neuropeptide Y gene in transgenic mice
(Elsevier, 1992-06)
Neuropeptide Y (NPY) is the most abundant neuropeptide detected in the mammalian brain, and is found throughout the central and peripheral nervous systems. This peptide is a proposed regulator of appetite, blood pressure, ...
Surrogate endpoint biomarkers for cervical cancer chemoprevention trials
(Wiley Subscription Services, Inc., A Wiley Company, 1995)
Cervical intraepithelia neoplasia (CIN) represents a spectrum of epithelial changes that provide an excellent model for developing chemopreventive interventions for cervical cancer. Possible drug effect surrogate endpoint ...
Proton and sodium MRI assessment of emerging tumor chemotherapeutic resistance
(John Wiley & Sons, Ltd., 2006-12)
The ultimate goal of any cancer therapy is to target the elimination of neoplastic cells. Although newer therapeutic strategies are in constant development, therapeutic assessment has been hampered by the inability to ...
Intrinsic difference in erythrocyte membrane in spontaneously hypertensive rats characterized by Na + and K + fluxes
(Springer-Verlag, 1983-09)
The goad of this study was to determine whether the elevated flux of sodium and potassium through the erythrocyte membrane of spontaneously hypertensive rats (SHR) is due to an intrinsic difference in the cell membrane or ...
A Bayesian hierarchical approach to multirater correlated ROC analysis
(John Wiley & Sons, Ltd., 2005)
In a common ROC study design, several readers are asked to rate diagnostics of the same cases processed under different modalities. We describe a Bayesian hierarchical model that facilitates the analysis of this study ...