Now showing items 1-2 of 2
Use of a gonadotropin-releasing hormone analog for protection against premature ovarian failure during cyclophosphamide therapy in women with severe lupus
(Wiley Subscription Services, Inc., A Wiley Company, 2005-09)
Objective Cyclophosphamide (CYC) therapy for systemic lupus erythematosus (SLE), a disease predominantly affecting women of childbearing age, causes an unacceptably high incidence of irreversible premature ovarian failure ...
Attenuation of autoimmune disease in fas-deficient mice by treatment with a cytotoxic benzodiazepine
(Wiley Subscription Services, Inc., A Wiley Company, 2003-03)
Objective Elimination of autoreactive cells relies on Fas-dependent activation-induced cell death mechanisms, an important component of peripheral tolerance. Defects in Fas or its cognate ligand lead to inefficient ...