Portal vein thrombosis and survival in patients with cirrhosis
dc.contributor.author | Englesbe, Michael J. | en_US |
dc.contributor.author | Kubus, James | en_US |
dc.contributor.author | Muhammad, Wajee | en_US |
dc.contributor.author | Sonnenday, Christopher J. | en_US |
dc.contributor.author | Welling, Theodore H. | en_US |
dc.contributor.author | Punch, Jeffrey D. | en_US |
dc.contributor.author | Lynch, Raymond J. | en_US |
dc.contributor.author | Marrero, Jorge A. | en_US |
dc.contributor.author | Pelletier, Shawn J. | en_US |
dc.date.accessioned | 2010-01-05T15:09:10Z | |
dc.date.available | 2011-03-01T16:26:45Z | en_US |
dc.date.issued | 2010-01 | en_US |
dc.identifier.citation | Englesbe, Michael J.; Kubus, James; Muhammad, Wajee; Sonnenday, Christopher J.; Welling, Theodore; Punch, Jeffrey D.; Lynch, Raymond J.; Marrero, Jorge A.; Pelletier, Shawn J. (2010). "Portal vein thrombosis and survival in patients with cirrhosis." Liver Transplantation 16(1): 83-90. <http://hdl.handle.net/2027.42/64526> | en_US |
dc.identifier.issn | 1527-6465 | en_US |
dc.identifier.issn | 1527-6473 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/64526 | |
dc.description.abstract | The effects of occlusive portal vein thrombosis (PVT) on the survival of patients with cirrhosis are unknown. This was a retrospective cohort study at a single center. The main exposure variable was the presence of occlusive PVT. The primary outcome measure was time-dependent mortality. A total of 3295 patients were analyzed, and 148 (4.5%) had PVT. Variables independently predictive of mortality from the time of liver transplant evaluation included age [hazard ratio (HR), 1.02; 95% confidence interval (CI), 1.01-1.03], Model for End-Stage Liver Disease (MELD) score (HR, 1.10; 95% CI, 1.08-1.11), hepatitis C (HR, 1.44; 95% CI, 1.24-1.68), and PVT (HR, 2.61; 95% CI, 1.97-3.51). Variables independently associated with the risk of mortality from the time of liver transplant listing included age (HR, 1.02; 95% CI, 1.01-1.03), transplantation (HR, 0.65; 95% CI, 0.50-0.81), MELD (HR, 1.08; 95% CI, 1.06-1.10), hepatitis C (HR, 1.50; 95% CI, 1.18-1.90), and PVT (1.99; 95% CI, 1.25-3.16). The presence of occlusive PVT at the time of liver transplantation was associated with an increased risk of death at 30 days (odds ratio, 7.39; 95% CI, 2.39-22.83). In conclusion, patients with cirrhosis complicated by PVT have an increased risk of death. Liver Transpl 16:83–90, 2010. © 2009 AASLD. | en_US |
dc.format.extent | 287974 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Surgery | en_US |
dc.title | Portal vein thrombosis and survival in patients with cirrhosis | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Surgery and Anesthesiology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Transplantation, Department of Surgery, University of Michigan, Ann Arbor, MI ; Telephone: 734-936-8363; FAX: 734-763-3187 ; University of Michigan Health System, 2926 Taubman Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0331 | en_US |
dc.contributor.affiliationum | Division of Transplantation, Department of Surgery, University of Michigan, Ann Arbor, MI | en_US |
dc.contributor.affiliationum | Division of Transplantation, Department of Surgery, University of Michigan, Ann Arbor, MI | en_US |
dc.contributor.affiliationum | Division of Transplantation, Department of Surgery, University of Michigan, Ann Arbor, MI | en_US |
dc.contributor.affiliationum | Division of Transplantation, Department of Surgery, University of Michigan, Ann Arbor, MI | en_US |
dc.contributor.affiliationum | Division of Transplantation, Department of Surgery, University of Michigan, Ann Arbor, MI | en_US |
dc.contributor.affiliationum | Division of Transplantation, Department of Surgery, University of Michigan, Ann Arbor, MI | en_US |
dc.contributor.affiliationum | Division of Gastroenterology, Department of Medicine, University of Michigan, Ann Arbor, MI | en_US |
dc.contributor.affiliationum | Division of Transplantation, Department of Surgery, University of Michigan, Ann Arbor, MI | en_US |
dc.identifier.pmid | 20035521 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/64526/1/21941_ftp.pdf | |
dc.identifier.doi | 10.1002/lt.21941 | en_US |
dc.identifier.source | Liver Transplantation | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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