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Electrocerebral Recovery During the Intracarotid Amobarbital Procedure: Influence of Interval Between Injections

dc.contributor.authorSelwa, Linda M.en_US
dc.contributor.authorBuchtel, Henry A.en_US
dc.contributor.authorHenry, Thomas R.en_US
dc.date.accessioned2010-04-01T14:49:28Z
dc.date.available2010-04-01T14:49:28Z
dc.date.issued1997-12en_US
dc.identifier.citationSelwa, Linda M.; Buchtel, Henry A.; Henry, Thomas R. (1997). "Electrocerebral Recovery During the Intracarotid Amobarbital Procedure: Influence of Interval Between Injections." Epilepsia 38(12): 1294-1299. <http://hdl.handle.net/2027.42/65275>en_US
dc.identifier.issn0013-9580en_US
dc.identifier.issn1528-1167en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/65275
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9578525&dopt=citationen_US
dc.description.abstractPurpose and Methods : During the intracarotid amobarbital procedure (IAP) at the University of Michigan, continuous scalp EEG monitoring guides the timing for presentation of memory items and postinjection testing. Most of our patients have undergone bilateral injections. The interval between injections varied from 22 to 60 min, depending on the test and recovery time, as well as the time to catheterize the second side. After noting a trend toward prolonged electro-graphic recovery following the second injection, we tested our clinical impression that recovery of the second hemisphere may be influenced by (a) the time between injections and (b) which hemisphere is injected first (epileptogenic or nonepileptogenic). To study these questions, we analyzed EEG recovery data from 48 consecutive IAPs. Approximately half the patients had the epileptogenic side injected first. Results : We found that (a) electrographic recovery after the second injection is prolonged if the interval between bilateral injections is less than 40 minutes and (b) electrographic recovery is more rapid after injection of the epileptogenic hemisphere. Conclusions : We now recommend waiting at least 45 min between injections. The pathophysiology of more prolonged amobarbital effect on the nonepileptogenic hemisphere than on the epileptogenic hemisphere remains unclear.en_US
dc.format.extent554104 bytes
dc.format.extent3110 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1997 International League Against Epilepsyen_US
dc.subject.otherAmobarbitalen_US
dc.subject.otherIntracarotiden_US
dc.subject.otherEpilepsyen_US
dc.subject.otherTemporal Lobeen_US
dc.subject.otherMemoryen_US
dc.subject.otherEpilepsy Partialen_US
dc.subject.otherInjectionsen_US
dc.subject.otherIntraarterialen_US
dc.titleElectrocerebral Recovery During the Intracarotid Amobarbital Procedure: Influence of Interval Between Injectionsen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Neurology, University of Michigan, Ann Arbor, Michigan, U.S.A.en_US
dc.contributor.affiliationum* Ann Arbor VA Medical Center, University of Michigan, Ann Arbor, Michigan, U.S.A.en_US
dc.contributor.affiliationum† Department of Psychiatry and Psychology, University of Michigan, Ann Arbor, Michigan, U.S.A.en_US
dc.contributor.affiliationum† Department of Neurology, Emory University, Ann Arbor, Michigan, U.S.A.en_US
dc.identifier.pmid9578525en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/65275/1/j.1528-1157.1997.tb00067.x.pdf
dc.identifier.doi10.1111/j.1528-1157.1997.tb00067.xen_US
dc.identifier.sourceEpilepsiaen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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