Interictal Spiking Increases with Sleep Depth in Temporal Lobe Epilepsy
dc.contributor.author | Malow, Beth A. | en_US |
dc.contributor.author | Lin, Xihong | en_US |
dc.contributor.author | Kushwaha, Ramesh | en_US |
dc.contributor.author | Aldrich, Michael S. | en_US |
dc.date.accessioned | 2010-04-01T14:57:48Z | |
dc.date.available | 2010-04-01T14:57:48Z | |
dc.date.issued | 1998-12 | en_US |
dc.identifier.citation | Malow, Beth A.; Lin, Xihong; Kushwaha, Ramesh; Aldrich, Michael S. (1998). "Interictal Spiking Increases with Sleep Depth in Temporal Lobe Epilepsy." Epilepsia 39(12): 1309-1316. <http://hdl.handle.net/2027.42/65422> | en_US |
dc.identifier.issn | 0013-9580 | en_US |
dc.identifier.issn | 1528-1167 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/65422 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9860066&dopt=citation | en_US |
dc.description.abstract | Purpose : To test the hypothesis that deepening sleep activates focal interictal epileptiform discharges (IEDs), we performed EEG-polysomnography in 21 subjects with medically refractory temporal lobe epilepsy. Methods: At the time of study, subjects were seizure-free for 224 h and were taking stable doses of antiepileptic medications (AEDs). Sleep depth was measured by log delta power (LDP). Visual sleep scoring and visual detection of IEDs also were performed. Logistic-regression analyses of IED occurrence in relation to LDP were carried out for two groups of subjects, nine with frequent IEDs (group 1) and 12 with rare IEDs (group 2). Results: The LDP differentiated visually scored non-rapid eye movement (NREM) sleep stages (p = 0.0001). The IEDs were most frequent in NREM stages 3/4 and least frequent in REM sleep. Within NREM sleep, in both groups, IEDs were more frequent at higher levels of LDP (p < 0.05). In group 1, after accounting for the level of LDP, IEDs were more frequent (a) on the ascending limb of LDP and with more rapid increases in LDP (p = 0.007), (b) in NREM than in REM sleep (p = 0.002), and (c) closer to sleep onset (p < 0.0001). Fewer than 1% of IEDs occurred within 10 s of an EEG arousal. Conclusions: Processes underlying the deepening of NREM sleep, including progressive hyperpolarization in thalamocortical projection neurons, may contribute to IED activation in partial epilepsy. Time from sleep onset and NREM versus REM sleep also influence IED occurrence. | en_US |
dc.format.extent | 878064 bytes | |
dc.format.extent | 3110 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | 1998 International League Against Epilepsy | en_US |
dc.subject.other | Sleep | en_US |
dc.subject.other | Epilepsy | en_US |
dc.subject.other | Electroencephalography | en_US |
dc.subject.other | Quantitative EEG | en_US |
dc.subject.other | Interictal Epileptiform Discharges | en_US |
dc.title | Interictal Spiking Increases with Sleep Depth in Temporal Lobe Epilepsy | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Clinical Neurophysiology Laboratory, Department of Neurology, University of Michigan Medical School, Ann Arbor, Michigan, U.S.A. | en_US |
dc.contributor.affiliationum | * Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, Michigan, U.S.A. | en_US |
dc.identifier.pmid | 9860066 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/65422/1/j.1528-1157.1998.tb01329.x.pdf | |
dc.identifier.doi | 10.1111/j.1528-1157.1998.tb01329.x | en_US |
dc.identifier.source | Epilepsia | en_US |
dc.identifier.citedreference | Kellaway P. Sleep and epilepsy. Epilepsia 1985 ; 26 : S15 – 30. | en_US |
dc.identifier.citedreference | Sato S, Dreifuss F, Penry J. The effect of sleep on spike-wave discharges in absence seizures. Neurology 1973 ; 23 : 1335 – 45. | en_US |
dc.identifier.citedreference | Montplaisir J, Laverdiere M, Saint-Hilaire J, Rouleau I. Nocturnal sleep recording in focal epilepsy: a study with depth electrodes. J Clin Neurophysiol 1987 ; 4 : 383 – 8. | en_US |
dc.identifier.citedreference | Wieser H. Temporal lobe epilepsy, sleep and arousal: stereo-EEG findings. In : Degan R, Rodin E, eds. Epilepsy, sleep and sleep deprivation. 2nd ed. Amsterdam : Elsevier, 1991 : 97 – 119. | en_US |
dc.identifier.citedreference | Wyler A. Epileptic neurons during sleep and wakefulness. Exp Neurol 1974, 42 : 593 – 608. | en_US |
dc.identifier.citedreference | Shouse M, Siegel J, Wu M, Szymusiak R, Momson A. Mechanism of seizure suppression during rapid-eye movement (REM) sleep in cats. Brain Res 1989 ; 505 : 271 – 82. | en_US |
dc.identifier.citedreference | Steriade M, McCormick D, Sejnowski T. Thalamocortical oscillations in the sleeping and aroused brain. Science 1993 ; 262 : 679 – 84. | en_US |
dc.identifier.citedreference | Sammaritano M, Gigli GL, Gotman J. Interictal spiking during wakefulness and sleep and the localization of foci in temporal lobe epilepsy. Neurology 1991 ; 41 : 29 – 7. | en_US |
dc.identifier.citedreference | Rossi G, Colicchio G, Pola P. Interictal epileptic activity during sleep: a stereo-EEG study in patients with partial epilepsy. Electroencephalogr Clin Neurophysiol 1984 ; 58 : 97 – 106. | en_US |
dc.identifier.citedreference | Lieb J, Joseph J, Engel J Jr, Walker J, Crandall P. Sleep state and seizure foci related to depth spike activity in patients with temporal lobe epilepsy. Electroencephalogr Clin Neurophysiol 1980 ; 49 : 538 – 57. | en_US |
dc.identifier.citedreference | Malow BA, Kushwaha R, Lin X, Morton K, Aldnch M. Relationship of interictal epileptiform discharges to sleep depth in partial epilepsy. Electroencephalogr Clin Neurophysiol 1997 ; 102 : 20 – 6. | en_US |
dc.identifier.citedreference | 12. Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes. Epilepsia 1981 ; 22 : 489 – 501. | en_US |
dc.identifier.citedreference | Agnew H, Webb W, Williams R. The first night effect: an EEG study of sleep. Psychophysiology 1966 ; 2263 – 6. | en_US |
dc.identifier.citedreference | Gotman J. Relationships between interictal spiking and seizures: human and experimental evidence. Can JNeurol Sci 1991 ; 18 : 573 – 6. | en_US |
dc.identifier.citedreference | Katz A, Marks DA, McCarthy G, Spencer SS. Does interictal spiking change prior to seizures ? Electroencephalogr Clin Neurophysiol 1991 ; 79 : 1534. | en_US |
dc.identifier.citedreference | Rechtschaffen A, Kales A. A manual of standardized terminology, techniques and scoring systems for sleep stages of human subjects. Los Angeles : UCLA Brain Information ServicelBrain Research Institute, 1968. | en_US |
dc.identifier.citedreference | 17. American Sleep Disorders Association. EEG arousals: scoring rules and examples: a preliminary report from the sleep disorders atlas task force of the American Sleep Disorders Association. Sleep 1992 : 15 : 173 – 84. | en_US |
dc.identifier.citedreference | Gloor P. Contributions of electroencephalography and electrocorticography in the neurosurgical treatment of the epilepsies. Adv Neurol 1975 ; 8 : 59 – 105. | en_US |
dc.identifier.citedreference | Diggle P, Liang K, Zeger S. Analysis of longitudinal data. Oxford : Oxford University Press, 1994 : 55 – 68. | en_US |
dc.identifier.citedreference | Lipsitz S, Kim K, Zhao L. Analysis of repeated categorical data using generalized estimating equations. Statistics Med 1994 ; 13 : 1149 – 63. | en_US |
dc.identifier.citedreference | Borbely A, Baumann F, Brandeis D, Strauch I, Lehmann D. Sleep deprivation: effect of sleep stages and EEG power density in man. Electroencephalogr Clin Neurophysiol 1981 ; 51 : 483 – 93. | en_US |
dc.identifier.citedreference | Frost J, Hrachovy R, Glaze D, McCully M. Sleep modulation of interictal spike configuration in untreated children with partial seizures. Epilepsia 1991 ; 32 : 341 – 6. | en_US |
dc.identifier.citedreference | Touchon J, Baldy-Moulinier M, Billiard M, Besset A, Cadilhac J. Sleep instability in temporal lobe epilepsy. In : Wolf P, Dam M, Janz D, Dreifuss F, eds. Advances in epileptology. New York Raven Press, 1987 : 709 – 11. | en_US |
dc.identifier.citedreference | Touchon J, Baldy-Moulinier M, Billiard M, Besset A, Cadilhac J. Sleep organization and epilepsy. In : Degen R, Rodin E, eds. Epilepsy, sleep and sleep deprivation. New York : Elsevier, 1991 : 73 – 81. | en_US |
dc.identifier.citedreference | Steriade M, Conteras D, Amzica F. Synchronized sleep oscillations and their paroxysmal developments. Trends Neurosci 1994 ; 17 : 199 – 208. | en_US |
dc.identifier.citedreference | Billiard M, Besset A, Zachariev Z, Touchon J, Baldy-Moulinier M, Cadilhac J. Relation of seizures and seizure discharges to sleep stages. In : Wolf P, Dam M, Janz D, Dreifuss F, eds. Advances in epileptology. New York Raven Press, 1987 ; 665 – 70. | en_US |
dc.identifier.citedreference | Borbely A. How can slow wave sleep best be measured ? In : Chase M, Roth T, eds. Slow wave sleep: its measurement and functional significance. Los Angeles : UCLA Brain Information Service, Brain Research Institute, 1990 : 21 – 2. | en_US |
dc.identifier.citedreference | Adachi N, Alarcon G, Binnie CD, Elwes RDC, Polkey CE, Reynolds EH. Predictive value of interictal epileptiform discharges during non-REM sleep on scalp EEG recordings for the lateralization of epileptogenesis. Epilepsia 1998 ; 39 : 628 – 32. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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