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Inherited thermostability variants of seven enzymes in a Japanese population
dc.contributor.authorSatoh, Chiyokoen_US
dc.contributor.authorNeel, James V.en_US
dc.contributor.authorMiura, A.en_US
dc.contributor.authorUeno, C.en_US
dc.contributor.authorArakawa, H.en_US
dc.contributor.authorOmine, H.en_US
dc.contributor.authorGoriki, Kazuakien_US
dc.contributor.authorFujita, Mikioen_US
dc.date.accessioned2010-04-01T15:06:20Z
dc.date.available2010-04-01T15:06:20Z
dc.date.issued1985-01en_US
dc.identifier.citationSATOH, C.; NEEL, J. V.; MIURA, A.; UENO, C.; ARAKAWA, H.; OMINE, H.; GORIKI, K.; FUJITA, M. (1985). "Inherited thermostability variants of seven enzymes in a Japanese population." Annals of Human Genetics 49(1): 11-22. <http://hdl.handle.net/2027.42/65570>en_US
dc.identifier.issn0003-4800en_US
dc.identifier.issn1469-1809en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/65570
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4073825&dopt=citationen_US
dc.description.abstractThe frequency of inherited variations in thermostability was investigated in a series of seven enzymes in a Japanese population. Among a total of 5930 determinations, nine variants were encountered. In each instance one parent exhibited a similar finding. It is suggested that this procedure should detect a high proportion of the variants of these enzymes characterized by amino acid substitutions not altering molecular charge. Failure to detect more such thermostability variants is interpreted to mean that electrophoresis not only detects amino acid substitutions altering molecular charge but also a considerable proportion of those that do not alter charge.en_US
dc.format.extent845178 bytes
dc.format.extent3110 bytes
dc.format.mimetypeapplication/pdf
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dc.publisherBlackwell Publishing Ltden_US
dc.rights1985 University College London and Blackwell Publishing Ltden_US
dc.titleInherited thermostability variants of seven enzymes in a Japanese populationen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationum*Department of Human Genetics, University of Michigan Medical School, Ann Arbor, MI 48109, USAen_US
dc.contributor.affiliationotherDivision of Biochemical Genetics, Department of Clinical Laboratories, Radiation Effects Research Foundation, 5-2 Hijiyama Park, Minami-Ward, Hiroshima 730, Japanen_US
dc.contributor.affiliationother†NÉe Akiko Yamashitaen_US
dc.identifier.pmid4073825en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/65570/1/j.1469-1809.1985.tb01671.x.pdf
dc.identifier.doi10.1111/j.1469-1809.1985.tb01671.xen_US
dc.identifier.sourceAnnals of Human Geneticsen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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