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Tetraenoic Species Are Conserved in Muscarinically Enhanced Inositide Turnover
dc.contributor.authorRooijen, Lucio A. A.en_US
dc.contributor.authorHajra, Amiya K.en_US
dc.contributor.authorAgranoff, Bernard W.en_US
dc.date.accessioned2010-04-01T15:09:58Z
dc.date.available2010-04-01T15:09:58Z
dc.date.issued1985-02en_US
dc.identifier.citationRooijen, Lucio A. A.; Hajra, Amiya K.; Agranoff, Bernard W. (1985). "Tetraenoic Species Are Conserved in Muscarinically Enhanced Inositide Turnover." Journal of Neurochemistry 44(2): 540-543. <http://hdl.handle.net/2027.42/65633>en_US
dc.identifier.issn0022-3042en_US
dc.identifier.issn1471-4159en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/65633
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2981288&dopt=citationen_US
dc.description.abstractCarbamylcholine enhances the labeling of phosphatidate and phosphatidylinositol from 32 P i in nerve endings. Approximately 74% of labeled phosphatidate and 85% of labeled phosphatidylinositol produced on muscarinic stimulation are accounted for by tetraenoic species, as detected by argentation TLC. Incubation of membranes derived from nerve endings with [Γ- 32 P]ATP under conditions of phosphodiesteratic degradation of endogenous polyphosphoinositides resulted in increased labeling of phosphatidate. Approximately 78% of the newly formed phosphatidate was in a tetraenoic fraction. It is concluded that in muscarinically stimulated nerve endings, the diacylglycerol moiety is conserved following diacylglycerol release from polyphosphoinositides through its resynthesis to inositol lipid via phosphatidate.en_US
dc.format.extent440302 bytes
dc.format.extent3110 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1985 International Society for Neurochemistryen_US
dc.subject.otherDiacylglycerolen_US
dc.subject.otherInositol Lipidsen_US
dc.subject.otherMuscarinic Receptoren_US
dc.subject.otherNerve Endingsen_US
dc.subject.otherPolyphosphoinositidesen_US
dc.subject.otherTetraenoic Lipidsen_US
dc.titleTetraenoic Species Are Conserved in Muscarinically Enhanced Inositide Turnoveren_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumNeuroscience Building, Mental Health Research Institute and Department of Biological Chemistry, The University of Michigan, Ann Arbor, Michigan, U.S.A.en_US
dc.identifier.pmid2981288en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/65633/1/j.1471-4159.1985.tb05446.x.pdf
dc.identifier.doi10.1111/j.1471-4159.1985.tb05446.xen_US
dc.identifier.sourceJournal of Neurochemistryen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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