Mechanisms of Unexplained Anemia in the Nursing Home
dc.contributor.author | Artz, Andrew S. | en_US |
dc.contributor.author | Fergusson, Dean | en_US |
dc.contributor.author | Drinka, Paul J. | en_US |
dc.contributor.author | Gerald, Melvin | en_US |
dc.contributor.author | Bidenbender, Rex | en_US |
dc.contributor.author | Lechich, Anthony | en_US |
dc.contributor.author | Silverstone, Felix | en_US |
dc.contributor.author | Mccamish, Mark A. | en_US |
dc.contributor.author | Dai, Jinlu | en_US |
dc.contributor.author | Keller, Evan T. | en_US |
dc.contributor.author | Ershler, William B. | en_US |
dc.date.accessioned | 2010-04-01T15:16:25Z | |
dc.date.available | 2010-04-01T15:16:25Z | |
dc.date.issued | 2004-03 | en_US |
dc.identifier.citation | Artz, Andrew S.; Fergusson, Dean; Drinka, Paul J.; Gerald, Melvin; Bidenbender, Rex; Lechich, Anthony; Silverstone, Felix; Mccamish, Mark A.; Dai, Jinlu; Keller, Evan; Ershler, William B. (2004). "Mechanisms of Unexplained Anemia in the Nursing Home." Journal of the American Geriatrics Society 52(3): 423-427. <http://hdl.handle.net/2027.42/65745> | en_US |
dc.identifier.issn | 0002-8614 | en_US |
dc.identifier.issn | 1532-5415 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/65745 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=14962159&dopt=citation | en_US |
dc.description.abstract | To characterize anemia in elderly nursing home residents. Design : Prospective multiinstitutional cohort study. Setting : Five nursing homes. Participants : From retrospective analysis, residents found to be anemic using chart review were prospectively randomized. Of the 81 residents enrolled, 60 were anemic. Measurements : Chart review for medical history and factors related to treatment or history of anemia, extensive laboratory evaluation for causes of anemia, and classification of anemia by two hematologists. Results : Among the 60 anemic residents, the causes of anemia were idiopathic (n=27), iron-deficiency (n=14), anemia associated with chronic disease (n=8), anemia of renal insufficiency (n=6), and other (n=5). The eryrthropoietin (EPO) response to anemia was lower in residents with idiopathic anemia (IA) than in those with iron-deficiency anemia, and this correlated with renal function as estimated using calculated creatinine clearance. In this elderly population, advancing age was not correlated with lower EPO response. Conclusion : IA is common in nursing home residents. A lower EPO response contributes to the high prevalence of anemia in this setting and may be due, in part, to occult renal dysfunction. | en_US |
dc.format.extent | 101622 bytes | |
dc.format.extent | 3110 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Science Inc | en_US |
dc.rights | © 2004 by the American Geriatrics Society | en_US |
dc.subject.other | Elderly | en_US |
dc.subject.other | Anemia | en_US |
dc.subject.other | Erythropoietin | en_US |
dc.subject.other | Renal Insufficiency | en_US |
dc.subject.other | Frail | en_US |
dc.title | Mechanisms of Unexplained Anemia in the Nursing Home | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Geriatrics | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Program of Immunology and Department of Pathology, University of Michigan, Ann Arbor, Michigan. | en_US |
dc.contributor.affiliationother | Institute for Advanced Studies in Aging and Geriatric Medicine, Washington, DC ; | en_US |
dc.contributor.affiliationother | National Geriatrics Research Consortium, Washington, DC ; | en_US |
dc.contributor.affiliationother | University of Chicago Medical Center, Chicago, Illinois ; | en_US |
dc.contributor.affiliationother | Ottawa Hospital Research Institute, Ottawa, Canada ; | en_US |
dc.contributor.affiliationother | Wisconsin Veterans Home, King, Wisconsin ; | en_US |
dc.contributor.affiliationother | Washington Nursing Facility, Washington, DC ; | en_US |
dc.contributor.affiliationother | Eastern Virginia Medical School, Norfolk, Virginia ; | en_US |
dc.contributor.affiliationother | Center Terence Cardinal Cooke Health Care Center, New York, New York ; | en_US |
dc.contributor.affiliationother | Parker Jewish Institute for Health Care and Rehabilitation, New Hyde Park, New York ; | en_US |
dc.contributor.affiliationother | Amgen, Inc., Thousand Oaks, California ; and | en_US |
dc.identifier.pmid | 14962159 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/65745/1/j.1532-5415.2004.52116.x.pdf | |
dc.identifier.doi | 10.1111/j.1532-5415.2004.52116.x | en_US |
dc.identifier.source | Journal of the American Geriatrics Society | en_US |
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dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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