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Neuropeptide Y and Peptide YY Inhibit Excitatory Synaptic Transmission in the Rat Dorsal Motor Nucleus of the Vagus
dc.contributor.authorBrowning, Kirsteen N.en_US
dc.contributor.authorTravagli, R. Albertoen_US
dc.date.accessioned2010-04-01T15:21:25Z
dc.date.available2010-04-01T15:21:25Z
dc.date.issued2003-06en_US
dc.identifier.citationBrowning, Kirsteen N.; Travagli, R. Alberto (2003). "Neuropeptide Y and Peptide YY Inhibit Excitatory Synaptic Transmission in the Rat Dorsal Motor Nucleus of the Vagus." The Journal of Physiology 549(3): 775-785. <http://hdl.handle.net/2027.42/65832>en_US
dc.identifier.issn0022-3751en_US
dc.identifier.issn1469-7793en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/65832
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12730340&dopt=citationen_US
dc.format.extent222035 bytes
dc.format.extent3110 bytes
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dc.publisherBlackwell Publishing Ltden_US
dc.rightsThe Physiological Society 2003en_US
dc.titleNeuropeptide Y and Peptide YY Inhibit Excitatory Synaptic Transmission in the Rat Dorsal Motor Nucleus of the Vagusen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelPhysiologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Internal Medicine – Gastroenterology and Physiology, University of Michigan, Ann Arbor, MI, USAen_US
dc.identifier.pmid12730340en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/65832/1/jphysiol.2003.042036.pdf
dc.identifier.doi10.1113/jphysiol.2003.042036en_US
dc.identifier.sourceThe Journal of Physiologyen_US
dc.identifier.citedreferenceAdrian TE, Savage AP, Sagor GR, Allen JM, Bacarese-Hamilton AJ, Tatemoto K, Polak JM & Bloom SR ( 1985 ). Effect of peptide YY on gastric, pancreatic, and biliary function in humans. Gastroenterology 89, 494 – 499.en_US
dc.identifier.citedreferenceArmstrong DM, Manley L, Haycock JW & Hersh LB ( 1990 ). Co-localization of choline acetyltransferase and tyrosine hydroxylase within neurons of the dorsal motor nucleus of the vagus. J Chem Neuroanat 3, 133 – 140.en_US
dc.identifier.citedreferenceBertolino M, Vicini S, Gillis RA & Travagli RA ( 1997 ). Presynaptic alpha-2 adrenoceptors inhibit excitatory synaptic transmission in rat brain stem. Am J of Physiol 272, G654 – 661.en_US
dc.identifier.citedreferenceBrowning KN, Renehan WE & Travagli RA ( 1999 ). Electrophysiological and morphological heterogeneity of rat dorsal vagal neurons which project to specific areas of the gastrointestinal tract. J Physiol 517, 521 – 532.en_US
dc.identifier.citedreferenceBrowning KN & Travagli RA ( 2001 ). The peptide TRH uncovers the presence of presynaptic 5-HT1A receptors via activation of a second messenger pathway in the rat dorsal vagal complex. J Physiol 531, 425 – 435.en_US
dc.identifier.citedreferenceBuell MG & Harding RK ( 1989 ). Effects of peptide YY on intestinal blood flow distribution and motility in the dog. Regul Pept 24, 195 – 208.en_US
dc.identifier.citedreferenceChen CH & Rogers RC ( 1995 ). Central inhibitory action of peptide YY on gastric motility in rats. Am J Physiol 269, R787 – 792.en_US
dc.identifier.citedreferenceChen CH & Rogers RC ( 1997 ). Peptide YY and the Y2 agonist PYY-(13–36) inhibit neurons of the dorsal motor nucleus of the vagus. Am J Physiol 273, R213 – 218.en_US
dc.identifier.citedreferenceChen CH, Rogers RC & Stephens RL Jr ( 1996 ). Intracisternal injection of peptide YY inhibits gastric emptying in rats. Regul Pept 61, 95 – 98.en_US
dc.identifier.citedreferenceChen CH, Stephens RL Jr & Rogers RC ( 1997 ). PYY and NPY control of gastric motility via action on Y1 and Y2 receptors in the DVC. Neurogastroenterol Motil 9, 109 – 116.en_US
dc.identifier.citedreferenceChi J, Kemerer J & Stephens RL Jr ( 1996 ). 5-HT in DVC: disparate effects on TRH analogue-stimulated gastric acid secretion, motility, and cytoprotection. Am J Physiol 271, R368 – 372.en_US
dc.identifier.citedreferenceDumont Y, Fournier A, St Pierre S, Schwartz TW & Quirion R ( 1990 ). Differential distribution of neuropeptide Y1 and Y2 receptors in the rat brain. Eur J Pharmacol 191, 501 – 503.en_US
dc.identifier.citedreferenceFujimiya M & Inui A ( 2000 ). Peptidergic regulation of gastrointestinal motility in rodents. Peptides 21, 1565 – 1582.en_US
dc.identifier.citedreferenceFujimiya M, Itoh E, Kihara N, Yamamoto I, Fujimura M & Inui A ( 2000 ). Neuropeptide Y induces fasted pattern of duodenal motility via Y 2 receptors in conscious fed rats. Am J Physiol Gastrointest Liver Physiol 278, G32 – 38.en_US
dc.identifier.citedreferenceFukuda A, Minami T, Nabekura J & Oomura Y ( 1987 ). The effects of noradrenaline on neurones in the rat dorsal motor nucleus of the vagus, in vitro. J Physiol 393, 213 – 231.en_US
dc.identifier.citedreferenceGeoghegan JG, Lawson DC, Cheng CA, Opara E, Taylor IL & Pappas TN ( 1993 ). Intracerebroventricular neuropeptide Y increases gastric and pancreatic secretion in the dog. Gastroenterology 105, 1069 – 1077.en_US
dc.identifier.citedreferenceGillis RA, Quest JA, Pagani FD & Norman WP ( 1989 ). Control centers in the central nervous system for regulating gastrointestinal motility. In Handbook of Physiology, section 6, The Gastrointestinal System, vol. I, Motility and Circulation, part 2, ed. Wood JD, pp. 621 – 683. The American Physiological Society, Bethesda, MD, USA.en_US
dc.identifier.citedreferenceGlaum SR, Miller RJ, Rhim H, Maclean D, Georgic LM, MacKenzie RG & Grundemar L ( 1997 ). Characterization of Y3 receptor-mediated synaptic inhibition by chimeric neuropeptide Y-peptide YY peptides in the rat brainstem. Br J Pharmacol 120, 481 – 487.en_US
dc.identifier.citedreferenceGrandt D, Dahms P, Schimiczek M, Eysselein VE, Reeve JR & Mentlein R ( 1993 ). Proteolytic processing by dipeptidyl aminopeptidase IV generates receptor selectivity for peptide YY. Med Klin 88, 143 – 145.en_US
dc.identifier.citedreferenceGrundemar L, Wahlestedt C & Reis DJ ( 1991 ). Long-lasting inhibition of the cardiovascular responses to glutamate and the baroreceptor reflex elicited by neuropeptide Y injected into the nucleus tractus solitarius of the rat. Neurosci Lett 122, 135 – 139.en_US
dc.identifier.citedreferenceHarfstrand A, Fuxe K, Terenius L & Kalia M ( 1987 ). Neuropeptide Y-immunoreactive perikarya and nerve terminals in the rat medulla oblongata: relationship to cytoarchitecture and catecholaminergic cell groups. J Comp Neurol 260, 20 – 35.en_US
dc.identifier.citedreferenceHornby PJ, ( 2001 ). Receptors and transmission in the brain-gut axis. II Excitatory amino acid receptors in the brain-gut axis. Am J Physiol Gastrointest Liver Physiol 280, G1055 – 1060.en_US
dc.identifier.citedreferenceIshiguchi T, Amano T, Matsubayashi H, Tada H, Fujita M & Takahashi T ( 2001 ). Centrally administered neuropeptide Y delays gastric emptying via Y2 receptors in rats. Am J Physiol Regul Integr Comp Physiol 281, R1522 – 1530.en_US
dc.identifier.citedreferenceJacques D, Cadieux A, Dumont Y & Quirion R ( 1995 ). Apparent affinity and potency of BIBP3226, a non-peptide neuropeptide Y receptor antagonist, on purported neuropeptide Y Y1, Y2 and Y3 receptors. Eur J Pharmacol 278, R3 – 5.en_US
dc.identifier.citedreferenceKapoor JR & Sladek CD ( 2001 ). Substance P and NPY differentially potentiate ATP and adrenergic stimulated vasopressin and oxytocin release. Am J Physiol Regul Integr Comp Physiol 280, R69 – 78.en_US
dc.identifier.citedreferenceKawakubo K, Yang H & Tache Y ( 2002 ). Gastric protective effect of peripheral PYY through PYY preferring receptors in anesthetized rats. Am J Physiol Gastrointest Liver Physiol 283, G1035 – 1041.en_US
dc.identifier.citedreferenceKhanna S, Sibbald JR & Day TA ( 1993 ). Neuropeptide Y modulation of A1 noradrenergic neuron input to supraoptic vasopressin cells. Neurosci Lett 161, 60 – 64.en_US
dc.identifier.citedreferenceLee CC & Miller RJ ( 1998 ). Is there really an NPY Y3 receptor? Regul Pept 75 – 76, 71 – 78.en_US
dc.identifier.citedreferenceLynch DR, Walker MW, Miller RJ & Snyder SH ( 1989 ). Neuropeptide Y receptor binding sites in rat brain: differential autoradiographic localizations with 125I-peptide YY and 125I- neuropeptide Y imply receptor heterogeneity. J Neurosci 9, 2607 – 2619.en_US
dc.identifier.citedreferenceMcCann MJ, Hermann GE & Rogers RC ( 1988 ). Dorsal medullary serotonin and gastric motility: enhancement of effects by thyrotropin-releasing hormone. J Auton Nerv Syst 25, 35 – 40.en_US
dc.identifier.citedreferenceMartire M & Pistritto G ( 1992 ). Neuropeptide Y interaction with the adrenergic transmission line: a study of its effect on alpha-2 adrenergic receptors. Pharmacol Res 25, 203 – 215.en_US
dc.identifier.citedreferenceMasuda M, Tomita H, Okubo K & Miyasaka K ( 1994 ). Vagal efferent nerve-dependent inhibitory action on pancreatic polypeptide and peptide YY in conscious rats: comparison with somatostatin. J Auton Nerv Syst 50, 131 – 138.en_US
dc.identifier.citedreferenceMatsuda M, Aono M, Moriga M & Okuma M ( 1993 ). Centrally administered NPY inhibits gastric emptying and intestinal transit in the rat. Dig Dis Sci 38, 845 – 850.en_US
dc.identifier.citedreferenceMendelowitz D & Kunze DL ( 1991 ). Identification and dissociation of cardiovascular neurons from the medulla for patch clamp analysis. Neurosci Lett 132, 217 – 221.en_US
dc.identifier.citedreferenceMentlein R, Dahms P, Grandt D & Kruger R ( 1993 ). Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV. Regul Pept 49, 133 – 144.en_US
dc.identifier.citedreferenceMichel MC, Beck-Sickinger A, Cox H, Doods HN, Herzog H, Larhammar D, Quirion R, Schwartz T & Westfall TC ( 1999 ). XVI International union of pharmacology reccommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol Rev 50, 143 – 150.en_US
dc.identifier.citedreferenceNaruse S, Kitagawa M, Ishiguro H & Hayakawa T ( 2002 ). Feedback regulation of pancreatic secretion by peptide YY. Peptides 23, 359 – 365.en_US
dc.identifier.citedreferencePappas TN, Tache Y & Debas HT ( 1985 ). Opposing central and peripheral actions of brain-gut peptides: a basis for regulation of gastric function. Surgery 98, 183 – 190.en_US
dc.identifier.citedreferencePitts DK, Kelland MD, Shen RY, Freeman AS & Chiodo LA ( 1990 ). Statistical analysis of dose-response curves in extracellular electrophysiological studies of single neurons. Synapse 5, 281 – 293.en_US
dc.identifier.citedreferenceRea MA, Aprison MH & Felten DL ( 1982 ). Catecholamines and serotonin in the caudal medulla of the rat: combined neurochemical-histofluorescence study. Brain Res Bull 9, 227 – 236.en_US
dc.identifier.citedreferenceRogers RC, Hermann GE & Travagli RA ( 1999 ). Brainstem pathways responsible for oesophageal control of gastric motility and tone in the rat. Journal of Physiology 514, 369 – 383.en_US
dc.identifier.citedreferenceRudolf K, Eberlein W, Engel W, Wieland HA, Willim KD, Entzeroth M, Wienen W, Beck-Sickinger AG & Doods HN ( 1994 ). The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226. Eur J Pharmacol 271, R11 – 13.en_US
dc.identifier.citedreferenceSawa T, Mameya S, Yoshimura M, Itsuno M, Makiyama K, Niwa M & Taniyama K ( 1995 ). Differential mechanism of peptide YY and neuropeptide Y in inhibiting motility of guinea-pig colon. Eur J Pharmacol 276, 223 – 230.en_US
dc.identifier.citedreferenceSheikh SP, ( 1991 ). Neuropeptide Y and peptide YY: major modulators of gastrointestinal blood flow and function. Am J Physiol 261, G701 – 715.en_US
dc.identifier.citedreferenceTer Horst GJ, Toes GJ & Van Willigen JD ( 1991 ). Locus coeruleus projections to the dorsal motor vagus nucleus in the rat. Neuroscience 45, 153 – 160.en_US
dc.identifier.citedreferenceTravagli RA, Gillis RA, Rossiter CD & Vicini S ( 1991 ). Glutamate and GABA-mediated synaptic currents in neurons of the rat dorsal motor nucleus of the vagus. Am J Physiol 260, G531 – 536.en_US
dc.identifier.citedreferenceTravagli RA, Hermann GE, Browning KN & Rogers RC ( 2003 ). Musings on the wanderer: what's new in our understanding of vago-vagal reflexes?: III. Activity-dependent plasticity in vago-vagal reflexes controlling the stomach. Am J Physiol Gastrointest Liver Physiol 284, G180 – 187.en_US
dc.identifier.citedreferenceTravagli RA & Rogers RC ( 2001 ). Receptors and transmission in the brain-gut axis: potential for novel therapies. V. Fast and slow extrinsic modulation of dorsal vagal complex circuits. Am J Physiol Gastrointest Liver Physiol 281, G595 – 601.en_US
dc.identifier.citedreferenceTricklebank MD, Forler C & Fozard JR ( 1984 ). The involvement of subtypes of the 5-HT1 receptor and of catecholaminergic systems in the behavioural response to 8-hydroxy-2-(di- n -propylamino)tetralin in the rat. Eur J Pharmacol 106, 271 – 282.en_US
dc.identifier.citedreferenceWiley J & Owyang C ( 1987 ). Neuropeptide Y inhibits cholinergic transmission in the isolated guinea pig colon: mediation through alpha-adrenergic receptors. Proc Natl Acad Sci U S A 84, 2047 – 2051.en_US
dc.identifier.citedreferenceYang H, ( 2002 ). Central and peripheral regulation of gastric acid secretion by peptide YY Peptides 23, 349 – 358.en_US
dc.identifier.citedreferenceYang H, Kawakubo K, Wong H, Ohning G, Walsh J & Tache Y ( 2000 ). Peripheral PYY inhibits intracisternal TRH-induced gastric acid secretion by acting in the brain. Am J Physiol Gastrointest Liver Physiol 279, G575 – 581.en_US
dc.identifier.citedreferenceYang H, Li WP, Reeve JR, Rivier J & Tache Y ( 1998 ). PYY-preferring receptor in the dorsal vagal complex and its involvement in PYY stimulation in gastric acid secretion in rats. Br J Pharmacol 123, 1549 – 1554.en_US
dc.identifier.citedreferenceYoneda M, Yokohama S, Tamori K, Sato Y, Nakamura K & Makino I ( 1997 ). Neuropeptide Y in the dorsal vagal complex stimulates bicarbonate-dependent bile secretion in rats. Gastroenterology 112, 1673 – 1680.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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