Dissociation of E-cadherin and Β-catenin in a mouse model of total parenteral nutrition: a mechanism for the loss of epithelial cell proliferation and villus atrophy
dc.contributor.author | Feng, Yongjia | en_US |
dc.contributor.author | Sun, Xiaoyi | en_US |
dc.contributor.author | Yang, Hua | en_US |
dc.contributor.author | Teitelbaum, Daniel H. | en_US |
dc.date.accessioned | 2010-04-01T15:30:10Z | |
dc.date.available | 2010-04-01T15:30:10Z | |
dc.date.issued | 2009-02-01 | en_US |
dc.identifier.citation | Feng, Yongjia; Sun, Xiaoyi; Yang, Hua; Teitelbaum, Daniel H. (2009). "Dissociation of E-cadherin and Β-catenin in a mouse model of total parenteral nutrition: a mechanism for the loss of epithelial cell proliferation and villus atrophy." The Journal of Physiology 587(3): 641-654. <http://hdl.handle.net/2027.42/65985> | en_US |
dc.identifier.issn | 0022-3751 | en_US |
dc.identifier.issn | 1469-7793 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/65985 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=19064618&dopt=citation | en_US |
dc.format.extent | 1232215 bytes | |
dc.format.extent | 3110 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | Journal compilation © 2009 The Physiological Society | en_US |
dc.title | Dissociation of E-cadherin and Β-catenin in a mouse model of total parenteral nutrition: a mechanism for the loss of epithelial cell proliferation and villus atrophy | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Physiology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Section of Pediatric Surgery, Department of Surgery, University of Michigan Medical School and the C. S. Mott Children's Hospital, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationother | Department of General Surgery, Xingqiao Hospital, Chongqing, China | en_US |
dc.identifier.pmid | 19064618 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/65985/1/jphysiol.2008.162719.pdf | |
dc.identifier.doi | 10.1113/jphysiol.2008.162719 | en_US |
dc.identifier.source | The Journal of Physiology | en_US |
dc.identifier.citedreference | Akiyama T ( 2000 ). Wnt/Β-catenin signaling. Cytokine Growth Factor Rev 11, 273 – 282. | en_US |
dc.identifier.citedreference | Basuroy S, Sheth P, Mansbach C & Rao R ( 2005 ). Acetaldehyde disrupts tight junctions and adherens junctions in human colonic mucosa: protection by EGF and L-glutamine. Am J Physiol Gastrointest Liver Physiol 289, G367 – G375. | en_US |
dc.identifier.citedreference | Batlle E, Henderson J, Beghtel H, Van Den Born M, Sancho E, Huls G, Meeldijk J, Robertson J, van de Wetering M, Pawson T & Clevers H ( 2002 ). Β-Catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell 111, 251 – 263. | en_US |
dc.identifier.citedreference | Bruewer M, Luegering A, Kucharzik T, Parkos CA, Madara JL, Hopkins AM & Nusrat A ( 2003 ). Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. J Immunol 171, 6164 – 6172. | en_US |
dc.identifier.citedreference | Clayburgh DR, Barrett TA, Tang Y, Meddings JB, Van Eldik LJ, Watterson DM, Clarke LL, Mrsny RJ & Turner JR ( 2005 ). Epithelial myosin light chain kinase–dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo. J Clin Invest 115, 2702 – 2715. | en_US |
dc.identifier.citedreference | D'Antiga L, Dhawan A, Davenport M, Mieli-Vergani G & Bjarnason I ( 1999 ). Intestinal absorption and permeability in paediatric short-bowel syndrome: a pilot study. J Pediatr Gastroenterol Nutr 29, 588 – 593. | en_US |
dc.identifier.citedreference | Daugherty R & Gottardi C ( 2007 ). Phospho-regulation of Β-catenin adhesion and signaling functions. Physiology 22, 303 – 309. | en_US |
dc.identifier.citedreference | DeWitt RC, Wu Y, Renegar KB & Kudsk KA ( 1999 ). Glutamine-enriched total parenteral nutrition preserves respiratory immunity and improves survival to a Pseudomonas pneumonia. J Surg Res 84, 13 – 18. | en_US |
dc.identifier.citedreference | Evans M, Jones D & Ziegler T ( 2005 ). Glutamine inhibits cytokine-induced apoptosis in human colonic epithelial cells via the pyrimidine pathway. Am J Physiol Gastrointest Liver Physiol 289, G388 – G396. | en_US |
dc.identifier.citedreference | Fang D, Hawke D, Zheng Y, Xia Y, Meisenhelder J, Nika H, Mills G, Kobayashi R, Hunter T & Lu Z ( 2007 ). Phosphorylation of Β-catenin by AKT promotes Β-catenin transcriptional activity. J Biol Chem 282, 11221 – 11229. | en_US |
dc.identifier.citedreference | Foligne B, Aissaoui S, Senegas-Balas FCC, Bernard P, Antoine J & Balas D ( 2001 ). Changes in cell proliferation and differentiation of adult rat small intestine epithelium after adrenalectomy: kinetic, biochemical, and morphological studies. Dig Dis Sci 46, 1236 – 1246. | en_US |
dc.identifier.citedreference | Frost P & Bihari D ( 1997 ). The route of nutritional support in the critically ill: physiological and economical considerations. Nutrition 13, 58S – 63S. | en_US |
dc.identifier.citedreference | Fukatsu K, Kudsk KA, Zarzaur BL, Wu Y, Hanna MK & DeWitt RC ( 2001 ). TPN decreases IL-4 and IL-10 mRNA expression in lipopolysaccharide stimulated intestinal lamina propria cells but glutamine supplementation preserves the expression. Shock 15, 318 – 322. | en_US |
dc.identifier.citedreference | Gates J & Peifer M ( 2005 ). Can 1000 reviews be wrong? Actin, a-catenin, and adherens junctions. Cell 123, 769 – 772. | en_US |
dc.identifier.citedreference | Gottardi Cara J & Gumbiner B ( 2001 ). Adhesion signaling: How Α-catenin interacts with its partners. Current Biol 11, 792 – 794. | en_US |
dc.identifier.citedreference | Gottardi C & Gumbiner B ( 2004 ). Distinct molecular forms of Β-catenin are targeted to adhesive or transcriptional complexes. J Cell Biol 167, 339 – 349. | en_US |
dc.identifier.citedreference | Gregorieff A, Pinto D, Begthel H, Destree O, Kielman M & Clevers H ( 2005 ). Expression pattern of Wnt signaling components in the adult intestine. Gastroenterology 129, 626 – 638. | en_US |
dc.identifier.citedreference | Grossmann J, Maxson J, Whitacre C, Orosz D, Berger N, Fiocchi C & Levine A ( 1998 ). New isolation technique to study apoptosis in human intestinal epithelial cells. Am J Pathol 153, 53 – 62. | en_US |
dc.identifier.citedreference | Gu Y, Wu ZH, Xie JX, Jin DY & Zhuo HC ( 2001 ). Effects of growth hormone (rhGH) and glutamine supplemented parenteral nutrition on intestinal adaptation in short bowel rats. Clin Nutrition 20, 159 – 166. | en_US |
dc.identifier.citedreference | Hart M, Concordet J, Lassot I, Albert I, del los Santos R, Durand H, Perret C, Rubinfeld B, Margottin F, Benarous R & Polakis P ( 1999 ). The F-box protein Β-TrCP associates with phosphorylated Β-catenin and regulates its activity in the cell. Curr Biol 9, 207 – 210. | en_US |
dc.identifier.citedreference | Haxhija E, Yang H, Spencer A, Koga H, Sun X & Teitelbaum D ( 2008 ). Modulation of mouse intestinal epithelial cell turnover in the absence of angiotensin coverting enzyme. Am J Physiol Gastrointestinal Liver Physiol 295, G88 – G98. | en_US |
dc.identifier.citedreference | He X, Yin T, Grindley J, Tian Q, Sato T, Tao W, Dirisina R, Porter-Westpfahl K, Hembree M, Johnson T, Wiedemann L, Barrett T, Hood L, Wu H & Li L ( 2007 ). PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat Genet 39, 189 – 198. | en_US |
dc.identifier.citedreference | Huber A & Weis W ( 2001 ). The structure of the Β-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by Β-catenin. Cell 10, 391 – 402. | en_US |
dc.identifier.citedreference | Illig KA, Ryan CK, Hardy DJ, Rhodes J, Locke W & Sax HC ( 1992 ). Total parenteral nutrition-induced changes in gut mucosal function: atrophy alone is not the issue. Surgery 112, 631 – 637. | en_US |
dc.identifier.citedreference | Itoh M, Nagafuchi A, Moroi S & Tsukita S ( 1997 ). Involvement of ZO-1 in cadherin-based cell adhesion through its direct binding to a catenin and actin filaments. J Cell Biol 138, 181 – 192. | en_US |
dc.identifier.citedreference | Ivanov AI, Nusrat A & Parkos CA ( 2004 ). Endocytosis of epithelial apical junctional proteins by a clathrin-mediated pathway into a unique storage compartment. Mol Biol Cell 15, 176 – 188. | en_US |
dc.identifier.citedreference | Kikuchi A ( 2000 ). Regulation of Β-catenin signaling in the Wnt pathway. Biochem Biophys Res Commun 268, 243 – 248. | en_US |
dc.identifier.citedreference | Kikuchi A, Kishida S & Yamamoto H ( 2006 ). Regulation of Wnt signaling by protein–protein interaction and post-translational modifications. Exp Mol Med 38, 1 – 10. | en_US |
dc.identifier.citedreference | Kiristioglu I, Antony P, Fan Y, Forbush B, Mosley RL, Yang H & Teitelbaum DH ( 2002 ). Total parenteral nutrition-associated changes in mouse intestinal intraepithelial lymphocytes. Digestive Dis Sci 47, 1147 – 1157. | en_US |
dc.identifier.citedreference | Kiristioglu I & Teitelbaum DH ( 1998 ). Alteration of the intestinal intraepithelial lymphocytes during total parenteral nutrition. J Surg Res 79, 91 – 96. | en_US |
dc.identifier.citedreference | Laprise P, Chailler P, Houde M, Beaulieu J, Boucher M & Rivard N ( 2002 ). Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation. J Biol Chem 277, 8226 – 8234. | en_US |
dc.identifier.citedreference | Larson S, Li J, Chung D & Evers B ( 2007 ). Molecular mechanisms contributing to glutamine-mediated intestinal cell survival. Am J Physiol Gastrointest Liver Physiol 293, G1262 – G1271. | en_US |
dc.identifier.citedreference | Li J, Kudsk KA, Gocinski B, Dent D, Glezer J & Langkamp-Henken B ( 1995 ). Effects of parenteral and enteral nutrition on gut-associated lymphoid tissue. J Trauma 39, 44 – 52. | en_US |
dc.identifier.citedreference | Liu C, Li Y, Semenov M, Han C, Baeg G, Tan Y, Zhang Z, Lin X & He X ( 2002 ). Control of Β-catenin phosphorylation/degradation by a dual-kinase mechanism. Cell 108, 837 – 847. | en_US |
dc.identifier.citedreference | Miller J, Hocking A, Brown J & Moon R ( 1999 ). Mechanism and function of signal transduction by the Wnt/Β-catenin and Wnt/Ca 2+ pathways. Oncogene 18, 7860 – 7872. | en_US |
dc.identifier.citedreference | Moore F, Feliciano D, Andrassy R, McArdle A, Booth F, Morgenstein-Wagner T, Kellum J, Welling R & Moore E ( 1992 ). Early enteral feeding, compared with parenteral, reduces postoperative septic complications. The results of a meta-analysis. Ann Surg 216, 172 – 183. | en_US |
dc.identifier.citedreference | Moore F, Moore E & Jones T ( 1989 ). TEN vs. TPN following major abdominal trauma: reduced septic morbidity. J Trauma 29, 916 – 923. | en_US |
dc.identifier.citedreference | Peifer M & Polakis P ( 2000 ). Wnt signaling in oncogenesis and embryogenesis – a look outside the nucleus. Science 287, 1606 – 1609. | en_US |
dc.identifier.citedreference | Perez-Moreno M ( 2003 ). Sticky business: orchestrating cellular signals at adherens junctions. Cell 112, 535 – 548. | en_US |
dc.identifier.citedreference | Peterson CA, Ney DM, Hinton PS & Carey HV ( 1996 ). Beneficial effects of insulin-like growth factor I on epithelial structure and function in parenterally fed rat jejunum. Gastroenterology 111, 1501 – 1508. | en_US |
dc.identifier.citedreference | Rimm D, Koslov E, Kebriaei P, Cianci C & Morrow J ( 1995 ). Α1 (E)-Catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc Natl Acad Sci U S A 92, 8813 – 8817. | en_US |
dc.identifier.citedreference | Schwarz B, Wang F, Shen L, Clayburgh D, Su L, Wang Y, Fu Y & Turner J ( 2007 ). LIGHT signals directly to intestinal epithelia to cause barrier dysfunction via cytoskeletal and endocytic mechanisms. Gastroenterology 132, 2383 – 2394. | en_US |
dc.identifier.citedreference | Scott J & Yap A ( 2006 ). Cinderella no longer: a-catenin steps out of cadherin's shadow. J Cell Sci 119, 4599 – 4605. | en_US |
dc.identifier.citedreference | Seth A, Basuroy S, Sheth P & Rao R ( 2004 ). L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer. Am J Physiol Gastrointest Liver Physiol 287, G510 – G517. | en_US |
dc.identifier.citedreference | Sheng H, Shao J, Townsend CJ & Evers B ( 2003 ). Phosphatidylinositol 3-kinase mediates proliferative signals in intestinal epithelial cells. Gut 52, 1472 – 1478. | en_US |
dc.identifier.citedreference | Sherr C ( 1996 ). Cancer cell cycles. Science 274, 1672 – 1677. | en_US |
dc.identifier.citedreference | Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R & Ben-Ze'ev A ( 1999 ). The cyclin D1 gene is a target of the Β-catenin/LEF-1 pathway. Proc Natl Acad Sci U S A 96, 5522 – 5527. | en_US |
dc.identifier.citedreference | Sipos F, Molnar B, Zagoni T, Berczi L & Tulassay Z ( 2005 ). Growth in epithelial cell proliferation and apoptosis correlates specifically to the inflammation activity of inflammatory bowel diseases: ulcerative colitis shows specific p53- and EGFR expression alterations. Dis Colon Rectum 48, 775 – 786. | en_US |
dc.identifier.citedreference | Sun X, Spencer AU, Yang H, Haxhija EQ & Teitelbaum DH ( 2006 ). Impact of caloric intake on parenteral nutrition-associated intestinal morphology and mucosal barrier function. JPEN J Parenter Enteral Nutr 30, 474 – 479. | en_US |
dc.identifier.citedreference | Sun X, Yang H, Nose K, Nose S, Haxhija EQ, Koga H, Feng Y & Teitelbaum DH ( 2008 ). Decline in intestinal mucosal IL-10 expression and decreased intestinal barrier function in a mouse model of total parenteral nutrition. Am J Physiol Gastrointest Liver Physiol 294, G139 – 147. | en_US |
dc.identifier.citedreference | Suzuki T, Seth A & Rao R ( 2007 ). Role of phospholipase CΓ-induced activation of protein kinase C (PKC ) and PKCΒI in epidermal growth factor-mediated protection of tight junctions from acetaldehyde in Caco-2 cell monolayers. J Biol Chem 283, 3574 – 3583. | en_US |
dc.identifier.citedreference | Takayama S, Rogatsky I, Schwarcz L & Darimont B ( 2006 ). The glucocorticoid receptor represses cyclin D1 by targeting the Tcf-Β-catenin complex. J Biol Chem 281, 17856 – 17863. | en_US |
dc.identifier.citedreference | Tang Y, Swietlicki EA, Jiang S, Buhman KK, Davidson NO, Burkly LC, Levin MS & Rubin DC ( 2006 ). Increased apoptosis and accelerated epithelial migration following inhibition of hedgehog signaling in adaptive small bowel postresection. Am J Physiol Gastrointest Liver Physiol 290, G1280 – G1288. | en_US |
dc.identifier.citedreference | Taurin S, Sandbo N, Qin Y, Browning D & Dulin N ( 2006 ). Phosphorylation of Β-catenin by cyclic AMP-dependent protein kinase. J Biol Chem 281, 9971 – 9976. | en_US |
dc.identifier.citedreference | Tutter A, Fryer C & Jones K ( 2001 ). Chromatin-specific regulation of LEF-1-Β-catenin transcription activation and inhibition in vitro. Genes Dev 15, 3342 – 3354. | en_US |
dc.identifier.citedreference | van Noort M & Clevers H ( 2002 ). TCF transcription factors, mediators of Wnt-signaling in development and cancer. Dev Biol 244, 1 – 8. | en_US |
dc.identifier.citedreference | van Noort M, Meeldijk J, Van Der Zee R, Destree O & Cleevers H ( 2002 ). Wnt signaling controls the phosphorylation status of Β-catenin. J Biol Chem 277, 17901 – 17905. | en_US |
dc.identifier.citedreference | Wildhaber BE, Lynn KN, Yang H & Teitelbaum DH ( 2002 ). Total parenteral nutrition-induced apoptosis in mouse intestinal epithelium: regulation by the Bcl-2 protein family. Pediatr Surg Int 18, 570 – 575. | en_US |
dc.identifier.citedreference | Wildhaber BE, Yang H, Haxhija EQ, Spencer AU & Teitelbaum DH ( 2005 ). Intestinal intraepithelial lymphocyte derived angiotensin converting enzyme modulates epithelial cell apoptosis. Apoptosis 10, 1305 – 1315. | en_US |
dc.identifier.citedreference | Yang H, Antony PA, Wildhaber BE & Teitelbaum DH ( 2004 ). Intestinal intraepithelial lymphocyte ΓΔ-T cell-derived keratinocyte growth factor modulates epithelial growth in the mouse. J Immunol 172, 4151 – 4158. | en_US |
dc.identifier.citedreference | Yang H, Fan Y & Teitelbaum DH ( 2003 a ). Intraepithelial lymphocyte-derived interferon-Γ evokes enterocyte apoptosis with parenteral nutrition in mice. Am J Physiol Gastrointest Liver Physiol 284, G629 – G637. | en_US |
dc.identifier.citedreference | Yang H, Finaly R & Teitelbaum DH ( 2003 b ). Alteration in epithelial permeability and ion transport in a mouse model of total parenteral nutrition. Crit Care Med 31, 1118 – 1125. | en_US |
dc.identifier.citedreference | Yang H, Kiristioglu I, Fan Y, Forbush B, Bishop DK, Antony PA, Zhou H & Teitelbaum DH ( 2002 ). Interferon-Γ expression by intraepithelial lymphocytes results in a loss of epithelial barrier function in a mouse model of total parenteral nutrition. Ann Surg 236, 226 – 234. | en_US |
dc.identifier.citedreference | Yang H, Soderholm JD, Larsson J, Permert J, Lindgren J & Wiren M ( 2000 ). Bidirectional supply of glutamine maintains enterocyte ATP content in the in vitro using chamber model. Int J Colorectal Dis 15, 291 – 296. | en_US |
dc.identifier.citedreference | Yang H, Wildhaber BE & Teitelbaum DH ( 2003 c ). Keratinocyte growth factor improves epithelial function after massive small bowel resection. J Parenter Enteral Nutr 27, 198 – 206. | en_US |
dc.identifier.citedreference | Zarzaur B, Ikeda S, Johnson C, Le T, Sacks G & Kudsk K ( 2002 a ). Mucosal immunity preservation with bombesin or glutamine is not dependent on mucosal addressin cell adhesion molecule-1 expression. JPEN J Parenter Enteral Nutr 25, 265 – 270. | en_US |
dc.identifier.citedreference | Zarzaur BL, Ikeda S, Johnson CD, Le T, Sacks G & Kudsk KA ( 2002 b ). Mucosal immunity preservation with bombesin or glutamine is not dependent on mucosal addressin cell adhesion molecule-1 expression. JPEN J Parenter Enteral Nutr 26, 265 – 270 ; discussion 270. | en_US |
dc.identifier.citedreference | Ziegler TR, Bazargan N, Leader LM & Martindale RG ( 2000 ). Glutamine and the gastrointestinal tract. Curr Opin Clin Nutr Metab Care 3, 355 – 362. | en_US |
dc.identifier.citedreference | Ziegler T, Luo M, EstÝvariz C, Moore IDA, Sitaraman S, Hao L, Bazargan N, Klapproth J, Tian J, Galloway J, Leader L, Jones D & Gewirtz A ( 2008 ). Detectable serum flagellin and lipopolysaccharide and upregulated anti-flagellin and lipopolysaccharide immunoglobulins in human short bowel syndrome. Am J Physiol Regul Integ Comp Physiol 294, R402 – R410. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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