View Item 

Show simple item record

Studies on the genetic and non-genetic (physiological) variation of human erythrocyte glutamic oxaloacetic transaminase
dc.contributor.authorWurzinger, K. H. (K. Hans)en_US
dc.contributor.authorMohrenweiser, Harvey W.en_US
dc.date.accessioned2010-04-01T15:32:28Z
dc.date.available2010-04-01T15:32:28Z
dc.date.issued1982-07en_US
dc.identifier.citationWURZINGER, K. H.; MOHRENWEISER, H. W. (1982). "Studies on the genetic and non-genetic (physiological) variation of human erythrocyte glutamic oxaloacetic transaminase." Annals of Human Genetics 46(3): 191-201. <http://hdl.handle.net/2027.42/66025>en_US
dc.identifier.issn0003-4800en_US
dc.identifier.issn1469-1809en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/66025
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7125592&dopt=citationen_US
dc.description.abstractThe thermostability profile of seven different electrophoretic variants of human erythrocyte GOT found in 13 different, unrelated families from a racially heterogeneous population was examined. The five different slow-variant and the two different fast-variant classes could be grouped into four different thermostability classes which were termed unstable, less stable, normal and more stable than normal. The thermostability differences among and within the electrophoretic variant classes permitted differentiation of the 13 individusals possessing an electrophoretic variant phenotype into a total of ten different variants.en_US
dc.format.extent685141 bytes
dc.format.extent3110 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1982 University College London and Blackwell Publishing Ltden_US
dc.titleStudies on the genetic and non-genetic (physiological) variation of human erythrocyte glutamic oxaloacetic transaminaseen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical Center, Ann Arbor, MI 48109en_US
dc.identifier.pmid7125592en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/66025/1/j.1469-1809.1982.tb00711.x.pdf
dc.identifier.doi10.1111/j.1469-1809.1982.tb00711.xen_US
dc.identifier.sourceAnnals of Human Geneticsen_US
dc.identifier.citedreferenceAly, H. E., Donald, E. A. & Simpson, M. H. W. ( 1971 ). Oral contraceptives and vitamin B 6 metabolism. Am. J. Clin. Nutr. 24, 297.en_US
dc.identifier.citedreferenceAyala, F. J., Powell, J. B., Tracey, M. L., Mourao, C. A. & Perez-Salas, S.. ( 1972 ). Enzymatic variability in the Drosophila willistoni Group. IV. Genetic varation in natural populations of Drosophia willistoni. Genetics 70, 113.en_US
dc.identifier.citedreferenceBanks, B. E. C., Doonan, S., Lawrence, A. J. & Vernon, C. A. ( 1968 ). The molecular weight and other properties of aspartate aminotransferase from pig heart muscle. Eur. J. Biochem. 5, 528.en_US
dc.identifier.citedreferenceBeutler, E. ( 1975 ). Red Cell Metabolism. A Manual of Biochemical Methods. Second edition, p. 160. New York : Grune & Stratton.en_US
dc.identifier.citedreferenceBonhomme, F. & Selander, R. K. ( 1978 ). Estimating total genic diversity in the house mouse. Biochem. Genet. 16, 287.en_US
dc.identifier.citedreferenceBosse, T. R. & Donald, E. A. ( 1979 ). The vitamin B 6 requirement in oral contraceptive users. I. Assessment by pyridoxal level and transferase activity in erythrocytes. Am. J. Clin. Nutr. 32, 1015.en_US
dc.identifier.citedreferenceBrewer, G. J. ( 1970 ). An Introduction to Isozyme Techniques, p. 186. New York : Academic Press.en_US
dc.identifier.citedreferenceCiblett S.-H., & Giblett, E. R. ( 1971 ). Genetic variation of soluble gluamic-oxaloacetic transaminase in man. Am. J. Hum Gent. 23, 419.en_US
dc.identifier.citedreferenceChen, S.-H., Malcolm, L. A., Yoshida, A. & Giblett, E. R. ( 1971 ). Phosphoglycerate kinase: an X-linked polymorphism in man. Am. J. Hum Genet. 23, 87.en_US
dc.identifier.citedreferenceEjderhamn, J. & Hamfelt, A. ( 1980 ). Pyridoxal phosphate concentration in blood in newborn infants and their mothers compared with the amount of extra pyridoxal taken during pregncy and breast feeding. Acta Paediatr. Scand. 69, 327.en_US
dc.identifier.citedreferenceFielek, S. & Mohrenweiser, H. W. ( 1979 ). Erythrocyte enzyme deficiencies assessed with a miniature centrifugal analyzer. Clin. Chem. 25, 384.en_US
dc.identifier.citedreferenceFolkers, K., Watanabe, T. & Ellis, J. M. ( 1977 ). Studies on the basal specific activity of the glutamic oxaloacetic transaminase of erythrocytes in relationship to a deficiency of vitamin B 6. Res. Commun. Chem. Path. Pharm. 17, 187.en_US
dc.identifier.citedreferenceGahr, M., Meves. H. & Schroter, W. ( 1979 ). Fetal properties in red blood cells of newborn infants. Pediat. Res. 13, 1231.en_US
dc.identifier.citedreferenceGorin, E., Taylor, Z. & Shafres, E. ( 1969 ). Glyceroneogenesis in adipose tissue of fasted, diabetic and triamcilnolone treated rats. Eur. J. Biochem. 8, 370.en_US
dc.identifier.citedreferenceHamelt, A. ( 1967 ). Pyridoxal phosphate concentration and aminotransferase activity in human blood cells. Clin. Chim. Acta 16, 19.en_US
dc.identifier.citedreferenceHurvitz, A. I. & Freedland, R. A. ( 1968 ). Influence of dietary protein on hydrocortisone-mediated adaptive enzymatic changes in rat liver. Biochem. Biophys. Acta 127, 548.en_US
dc.identifier.citedreferenceIshimoto, G. & Kuwata, M. ( 1974 ). Studies on human gluamic-oxaloacetic trasaminase variation, including enzyme patterns in some non-human primates. Jap. J. Hum. Genet. 18, 364.en_US
dc.identifier.citedreferenceJenkins, W. T., Yphantis, D. A. & Sizer, I. W. ( 1959 ). Glutamic aspartic transaminase. I. Assay, purification, and general properties. J. Biol. Chem. 234, 51.en_US
dc.identifier.citedreferenceLumeng, L., Cleary, R. E., Wagner, R., Ycu, P. L. & Li, T. K. ( 1976 ). Adequacy of vitamin B 6 supplementation during pregnancy: a prospective study. Am. J. Clin. Nutr. 29, 1376.en_US
dc.identifier.citedreferenceMagee, S. C. & Phillips, A. T. ( 1971 ). Molecular properties of the multiple asparte aminotransferases purified from rat brain. Biochemistry 10, 3397.en_US
dc.identifier.citedreferenceMartinez-Carrion, M., Turano, C., Chiancone, E., Bossa, R., Giartosio, A., Riva, F. & Fasella, P. ( 1967 ). Isolation and characterization of multiple forms of glutamate-aspartate aminotransferase from pig heart. J. Biol. Chem 242, 2397.en_US
dc.identifier.citedreferenceMohrenweiser, H. W. ( 1981 ). Frequency of enzyme deficiency variants in erythrocytes of newborn infants. Proc. Natn. Acad. Sci., USA 78, 5046.en_US
dc.identifier.citedreferenceMohrenweiser, H. W. & Neel, J. V. ( 1981 ). Frequency of thermostability variants: estimation of total ‘rare’ variant frequency in human populations. Proc. Natn. Acad. Sci., USA 78, 5729.en_US
dc.identifier.citedreferenceMohrenweiser, H. W., Fielek, S. & Wurzinger, K. H. ( 1981 ). Characteristics of enzymes of erythrocytes from newborn infants and adults: activity, thermostability and electrophoretic profile as a function of cell age. Am. J. Hematol. 11, 125.en_US
dc.identifier.citedreferenceNisselbaum, J. S. & Bodansky, O. ( 1964 ). Immunochemical and kinetic properties of anionic and cationic glutamic-oxaloacetic transaminases sepated from human heart and human liver. J. Biol. Chem. 239, 4232.en_US
dc.identifier.citedreferencePoulik, M. D. ( 1957 ). Starch gel electrophoresis in a discontinuous system of buffers. Nature, Lond. 180, 1477.en_US
dc.identifier.citedreferenceRose, D. P., Strong, R., Adams, P. W. & Harding, P. E. ( 1972 ). Experimental vitamin B 6 deficiency and the effect of oestrogen containing oral contraceptives on tryptophan metabolism and vitamin B 6 requirements. Clin. Sci 42, 465.en_US
dc.identifier.citedreferenceRose, D. P., Strong, R., Folkard, J. & Adams, P. W. ( 1973 ). Erythrocyte aminotransferase activities in women using oral contraceptives and the effect of vitamin B 6 supplementation. Am. J. Clin. Nutr. 26, 48.en_US
dc.identifier.citedreferenceSass, M. D., Vorsanger, E. & Spear, P. W. ( 1964 ). Enzyme activity as an indicator of red cell age. Clin. Chim. Acta. 10, 21.en_US
dc.identifier.citedreferenceSatoh, C. & Mohrenweiser, H. W. ( 1979 ). Genetic heterogeneity within an electrophoretic phenotype of phosphoglucose isomerase in a Japanese population. Ann. Hum. Genet. 42, 283.en_US
dc.identifier.citedreferenceScott, E. M. & Wright, R. C. ( 1981 ). An alternate method for demonstration of erythrocytic aminotransferases on starch gels. Am. J. Hum. Genet. 33, 561.en_US
dc.identifier.citedreferenceSelander, R. K., Smith, M. H., Yang, S. Y., Johnson, W. E. & Gentry, J. B. ( 1971 ). Biochemical polymorphism and systematics in the genus Peromysus. Univer. Texas Stud. Genet. 6, 49 – 90.en_US
dc.identifier.citedreferenceSingh, R., Hubby, J. L. & Lewontin, R. C. ( 1974 ). Molecular heterosis for heat sensitive enzyme alleles. Proc. Natn. Acad. Sci., USA. 71, 1808.en_US
dc.identifier.citedreferenceSolomon, L. R. & Hillman, R. S. ( 1979 ). Regulation of vitamin B 6 metabolism in human red cells. Am. J. Clin. Nutr. 32, 1824.en_US
dc.identifier.citedreferenceTeng, Y. S., Tan, S. G., Lopez, C. G., Ng, T. & Lie-Injo, L. E. ( 1978 ). Genetic makers in Malaysians: variants of soluble and mitochondrial glutamic oxaloacetic transaminase and salivary and pancreatic amylase, phosphoglucomutase III and saliva esterase polymorphisms. Hum. Genet. 41, 347.en_US
dc.identifier.citedreferenceWada, H. & Morino, Y. ( 1964 ). Compartive glutamic oxaloacetic transaminases from the mitochondrial and soluble fractions of mammalian tissues. Vitamin Horm. 22, 411.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
j.1469-1809.1982.tb00711.x.pdf
Size:
669.0KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe its collections in a way that respects the people and communities who create, use, and are represented in them. We encourage you to Contact Us anonymously if you encounter harmful or problematic language in catalog records or finding aids. More information about our policies and practices is available at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.