Limited access: U-M users only
Access by request
Access via HathiTrust
Access via FulcrumA Varying-Coefficient Cox Model for the Effect of Age at a Marker Event on Age at Menopause
| dc.contributor.author | Nan, Bin | en_US |
| dc.contributor.author | Lin, Xihong | en_US |
| dc.contributor.author | Lisabeth, Lynda D. | en_US |
| dc.contributor.author | Harlow, Siob n D. | en_US |
| dc.date.accessioned | 2010-04-01T15:33:34Z | |
| dc.date.available | 2010-04-01T15:33:34Z | |
| dc.date.issued | 2005-06 | en_US |
| dc.identifier.citation | Nan, Bin; Lin, Xihong; Lisabeth, Lynda D.; Harlow, Siob n D. (2005). "A Varying-Coefficient Cox Model for the Effect of Age at a Marker Event on Age at Menopause." Biometrics 61(2): 576-583. <http://hdl.handle.net/2027.42/66044> | en_US |
| dc.identifier.issn | 0006-341X | en_US |
| dc.identifier.issn | 1541-0420 | en_US |
| dc.identifier.uri | https://hdl.handle.net/2027.42/66044 | |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=16011707&dopt=citation | en_US |
| dc.description.abstract | It is of recent interest in reproductive health research to investigate the validity of a marker event for the onset of menopausal transition and to estimate age at menopause using age at the marker event. We propose a varying-coefficient Cox model to investigate the association between age at a marker event, defined as a specific bleeding pattern change, and age at menopause, where both events are subject to censoring and their association varies with age at the marker event. Estimation proceeds using the regression spline method. The proposed method is applied to the Tremin Trust data to evaluate the association between age at onset of the 60-day menstrual cycle and age at menopause. The performance of the proposed method is evaluated using a simulation study. | en_US |
| dc.format.extent | 273103 bytes | |
| dc.format.extent | 3110 bytes | |
| dc.format.mimetype | application/pdf | |
| dc.format.mimetype | text/plain | |
| dc.publisher | Blackwell Publishing | en_US |
| dc.rights | The International Biometric Society, 2005 | en_US |
| dc.subject.other | B -Splines | en_US |
| dc.subject.other | Cox Regression | en_US |
| dc.subject.other | Generalized Cross-validation | en_US |
| dc.subject.other | Marker Events | en_US |
| dc.subject.other | Nonparametric Regression | en_US |
| dc.subject.other | Survival Analysis | en_US |
| dc.subject.other | Time-dependent Covariates | en_US |
| dc.title | A Varying-Coefficient Cox Model for the Effect of Age at a Marker Event on Age at Menopause | en_US |
| dc.type | Article | en_US |
| dc.rights.robots | IndexNoFollow | en_US |
| dc.subject.hlbsecondlevel | Mathematics | en_US |
| dc.subject.hlbtoplevel | Science | en_US |
| dc.description.peerreviewed | Peer Reviewed | en_US |
| dc.contributor.affiliationum | Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, U.S.A. | en_US |
| dc.contributor.affiliationum | Department of Neurology, University of Michigan, Ann Arbor, Michigan 48109, U.S.A. | en_US |
| dc.contributor.affiliationum | Department of Epidemiology, University of Michigan, Ann Arbor, Michigan 48109, U.S.A. | en_US |
| dc.identifier.pmid | 16011707 | en_US |
| dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/66044/1/j.1541-0420.2005.030905.x.pdf | |
| dc.identifier.doi | 10.1111/j.1541-0420.2005.030905.x | en_US |
| dc.identifier.source | Biometrics | en_US |
| dc.identifier.citedreference | Crowley, J. and Hu, M. ( 1977 ). Covariance analysis of heart transplant survival data. Journal of the American Statistical Association 72, 27 36. | en_US |
| dc.identifier.citedreference | Hastie, T. J. and Tibshirani, R. J. ( 1990 ). Generalized Additive Models. London : Chapman & Hall. | en_US |
| dc.identifier.citedreference | Hastie, T. and Tibshirani, R. ( 1993 ). Varying-coefficient models. Journal of the Royal Statistical Society, Series B 55, 757 796. | en_US |
| dc.identifier.citedreference | Huang, J. H. ( 2003 ). Local asymptotics for polynomial spline regression. Annals of Statistics 31, 1600 1635. | en_US |
| dc.identifier.citedreference | Joly, P., Commenges, D., Helmer, C., and Letenneur, L. ( 2002 ). A penalized likelihood approach for an illness-death model with interval-censored data: Application to age-specific incidence of dementia. Biostatistics 3, 433 443. | en_US |
| dc.identifier.citedreference | Kalbfleisch, J. D. and Prentice, R. L. ( 2002 ). The Statistical Analysis of Failure Time Data, 2nd edition. Hoboken, New Jersey : John Wiley & Sons. | en_US |
| dc.identifier.citedreference | Lefkopoulou, M. and Zelen, M. ( 1995 ). Intermediate clinical events, surrogate markers and survival. Lifetime Data Analysis 1, 73 85. | en_US |
| dc.identifier.citedreference | Lisabeth, L. D., Harlow, S. D., Gillespie, B., Lin, X., and Sowers, M. F. ( 2004 ). Staging reproductive aging: A comparison of proposed bleeding criteria for the menopausal transition. Menopause 11, 186 197. | en_US |
| dc.identifier.citedreference | Little, R. J. A. and Rubin, D. B. ( 2002 ). Statistical Analysis with Missing Data. Hoboken, New Jersey : John Wiley & Sons. | en_US |
| dc.identifier.citedreference | Marzec, L. and Marzec, P. ( 1997 ). On fitting Cox's regression model with time-dependent coefficients. Biometrika 84, 901 908. | en_US |
| dc.identifier.citedreference | Mitchell, E. S., Woods, N. F., and Mariella, A. ( 2000 ). Three stages of the menopausal transition from the Seattle Midlife Women's Health Study: Toward a more precise definition. Menopause 7, 334 349. | en_US |
| dc.identifier.citedreference | Murphy, S. A. and Sen, P. K. ( 1991 ). Time-dependent coefficients in a Cox-type regression model. Stochastic Processes and Their Applications 39, 153 180. | en_US |
| dc.identifier.citedreference | Nam, C. M. and Zelen, M. ( 2001 ). Comparing the survival of two groups with an intermediate clinical event. Lifetime Data Analysis 7, 5 19. | en_US |
| dc.identifier.citedreference | O'Sullivan, F. ( 1988 ). Nonparametric estimation of relative risk using splines and cross-validation. SIAM Journal on Scientific and Statistical Computing 9, 531 542. | en_US |
| dc.identifier.citedreference | Paik, M. C. and Tsai, W. Y. ( 1997 ). On using the Cox proportional hazards model with missing covariates. Biometrika 84, 579 593. | en_US |
| dc.identifier.citedreference | Soules, M. R., Sherman, S., Parrott, E. P., Rebar, R., Santoro, N., Utian, W., and Woods, N. ( 2001 ). Executive summary: Stages of reproductive aging workshop. Fertility and Sterility 76, 874 878. | en_US |
| dc.identifier.citedreference | Taffe, J. and Dennerstein, L. ( 2001 ). Menstrual patterns leading to final menstrual period. Menopause 9, 32 40. | en_US |
| dc.identifier.citedreference | Therneau, T. M. and Grambsch, P. M. ( 2000 ). Modeling Survival Data: Extending the Cox Model. New York : Springer-Verlag. | en_US |
| dc.identifier.citedreference | Treloar, A. E., Boynton, R. E., Behn, B. G., and Brown, B. W. ( 1967 ). Variation of the human menstrual cycle through reproductive life. International Journal of Fertility 12, 77 126. | en_US |
| dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.