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Oligodendrocyte-myelin glycoprotein (OMgp) is an inhibitor of neurite outgrowth
dc.contributor.authorKottis, Vickyen_US
dc.contributor.authorThibault, Pierreen_US
dc.contributor.authorMikol, Daniel D.en_US
dc.contributor.authorXiao, Zhi-Chengen_US
dc.contributor.authorZhang, Rulinen_US
dc.contributor.authorDergham, Paulineen_US
dc.contributor.authorBraun, Peter E.en_US
dc.date.accessioned2010-04-01T15:34:52Z
dc.date.available2010-04-01T15:34:52Z
dc.date.issued2002-09en_US
dc.identifier.citationKottis, Vicky; Thibault, Pierre; Mikol, Daniel; Xiao, Zhi-Cheng; Zhang, Rulin; Dergham, Pauline; Braun, Peter E. (2002). "Oligodendrocyte-myelin glycoprotein (OMgp) is an inhibitor of neurite outgrowth." Journal of Neurochemistry 82(6): 1566-1569. <http://hdl.handle.net/2027.42/66067>en_US
dc.identifier.issn0022-3042en_US
dc.identifier.issn1471-4159en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/66067
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12354307&dopt=citationen_US
dc.description.abstractA protein fraction purified from bovine brain myelin, previously called arretin because of its ability to inhibit neurite outgrowth, has been identified as consisting predominantly of oligodendrocyte-myelin glycoprotein (OMgp). We show that it is a potent inhibitor of neurite outgrowth from rat cerebellar granule and hippocampal cells; from dorsal root ganglion explants in which growth cone collapse was observed; from rat retinal ganglion neurons; and from NG108 and PC12 cells. OMgp purified by a different procedure from both mouse and human myelin behaves identically in all bioassays tested.en_US
dc.format.extent161924 bytes
dc.format.extent3110 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Science Ltden_US
dc.rights2002 International Society for Neurochemistryen_US
dc.subject.otherArretinen_US
dc.subject.otherMyelin Inhibitorsen_US
dc.subject.otherNerve Regenerationen_US
dc.subject.otherNeurite Outgrowthen_US
dc.subject.otherOMgpen_US
dc.titleOligodendrocyte-myelin glycoprotein (OMgp) is an inhibitor of neurite outgrowthen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationum† Department of Neurology, University of Michigan, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationother* Department of Biochemistry, McGill University, Montreal, Quebec, Canadaen_US
dc.contributor.affiliationother† Institute for Biological Sciences, National Research Council, Ottawa, Canadaen_US
dc.contributor.affiliationother§ Department of Pathology, UniversitÉ de MontrÉal, Montreal, Quebec, Canadaen_US
dc.identifier.pmid12354307en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/66067/1/j.1471-4159.2002.01146.x.pdf
dc.identifier.doi10.1046/j.1471-4159.2002.01146.xen_US
dc.identifier.sourceJournal of Neurochemistryen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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