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Cause of Death in Older Men After the Diagnosis of Prostate Cancer

dc.contributor.authorKetchandji, Melanieen_US
dc.contributor.authorKuo, Yong-Fangen_US
dc.contributor.authorShahinian, Vahakn B.en_US
dc.contributor.authorGoodwin, James S.en_US
dc.date.accessioned2010-04-01T15:36:41Z
dc.date.available2010-04-01T15:36:41Z
dc.date.issued2009-01en_US
dc.identifier.citationKetchandji, Melanie; Kuo, Yong-Fang; Shahinian, Vahakn B.; Goodwin, James S. (2009). "Cause of Death in Older Men After the Diagnosis of Prostate Cancer." Journal of the American Geriatrics Society 57(1): 24-30. <http://hdl.handle.net/2027.42/66098>en_US
dc.identifier.issn0002-8614en_US
dc.identifier.issn1532-5415en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/66098
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=19054189&dopt=citationen_US
dc.description.abstractTo compare survival and cause of death in men aged 65 and older diagnosed with prostate cancer and with survival and cause of death in a noncancer control population. DESIGN : Retrospective cohort from a population-based tumor registry linked to Medicare claims data. SETTING : Eleven regions of the Surveillance, Epidemiology and End Results (SEER) Tumor Registry. PARTICIPANTS : Men aged 65 to 84 (N=208,601) diagnosed with prostate cancer from 1988 through 2002 formed the basis for different analytical cohorts. MEASUREMENTS : Survival as a function of stage and tumor grade (low, Gleason grade<7; moderate, grade=7; and high, grade=8–10) was compared with survival in men without any cancer using Cox proportional hazards regression. Cause of death according to stage and tumor grade were compared using chi-square statistics. RESULTS : Men with early-stage prostate cancer and with low- to moderate-grade tumors (59.1% of the entire sample) experienced a survival not substantially worse than men without prostate cancer. In those men, cardiovascular disease and other cancers were the leading causes of death. CONCLUSION : The excellent survival of older men with early-stage, low- to moderate-grade prostate cancer, along with the patterns of causes of death, implies that this population would be well served by an ongoing focus on screening and prevention of cardiovascular disease and other cancers.en_US
dc.format.extent149049 bytes
dc.format.extent3110 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Incen_US
dc.rightsJournal compilation 2009 The American Geriatrics Society/Wiley Periodicals, Inc.en_US
dc.subject.otherProstate Canceren_US
dc.subject.otherMortalityen_US
dc.subject.otherSurvival and Comorbiditiesen_US
dc.titleCause of Death in Older Men After the Diagnosis of Prostate Canceren_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelGeriatricsen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Internal Medicine, University of Michigan Health System, Ann Arbor, Michigan.en_US
dc.contributor.affiliationotherUniversity of Texas Medical Branch, Galveston, Texas ;en_US
dc.contributor.affiliationotherSealy Center on Aging ; anden_US
dc.identifier.pmid19054189en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/66098/1/j.1532-5415.2008.02091.x.pdf
dc.identifier.doi10.1111/j.1532-5415.2008.02091.xen_US
dc.identifier.sourceJournal of the American Geriatrics Societyen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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