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Distribution of Protein I, a Synapse-Specific Phosphoprotein, and Adenylate Cyclase in the Rat Spinal Cord
dc.contributor.authorUeda, Tetsufumien_US
dc.contributor.authorStratford, Carol A.en_US
dc.contributor.authorLarson, Jamesen_US
dc.date.accessioned2010-04-01T15:37:15Z
dc.date.available2010-04-01T15:37:15Z
dc.date.issued1981-01en_US
dc.identifier.citationUeda, Tetsufumi; Stratford, Carol A.; Larson, James (1981). "Distribution of Protein I, a Synapse-Specific Phosphoprotein, and Adenylate Cyclase in the Rat Spinal Cord." Journal of Neurochemistry 36(1): 293-296. <http://hdl.handle.net/2027.42/66108>en_US
dc.identifier.issn0022-3042en_US
dc.identifier.issn1471-4159en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/66108
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6780661&dopt=citationen_US
dc.description.abstractThe longitudinal and transverse distributions of the synapse-specific phosphoprotein Protein I and adenylate cyclase in the rat spinal cord were studied. Protein I was found to be enriched in all cervical and midlumbar (L 3 -L 5 ) segments, and sparse in midthoracic and sacral segments. Adenylate cyclase activity was high in all cervical and lumbosacral segments, and low in mid-thoracic segments. Cross-sectionally, both Protein I and adenylate cyclase were more enriched in the dorsal half than in the ventral half in the various segments studied. The similar topographical distributions of Protein 1 and adenylate cyclase in the spinal cord support the idea that adenylate cyclase may be intimately associated with Protein I in the nervous system, and could thereby regulate the state of in vivo phosphorylation of Protein I through formation of cyclic AMP.en_US
dc.format.extent361202 bytes
dc.format.extent3110 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1981 International Society for Neurochemistryen_US
dc.subject.otherCyclic AMPen_US
dc.subject.otherRegulated Phosphoproteinen_US
dc.subject.otherProtein Ien_US
dc.subject.otherSynapseen_US
dc.subject.otherAdenylate Cyclaseen_US
dc.subject.otherSpinal Corden_US
dc.titleDistribution of Protein I, a Synapse-Specific Phosphoprotein, and Adenylate Cyclase in the Rat Spinal Corden_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumMental Health Research Institute and the Departments of Psychiatry and Pharmacology. The University of Michigan, Ann Arbor, Michigan, U.S.A.en_US
dc.identifier.pmid6780661en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/66108/1/j.1471-4159.1981.tb02407.x.pdf
dc.identifier.doi10.1111/j.1471-4159.1981.tb02407.xen_US
dc.identifier.sourceJournal of Neurochemistryen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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