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The Use of a Rapid Enzymatic Assay in the Field for the Detection of Infections Associated with Adult Periodontitis

dc.contributor.authorBretz, Walter A.en_US
dc.contributor.authorEklund, Stephen A.en_US
dc.contributor.authorRadicchi, Ronalden_US
dc.contributor.authorSchork, Michael A.en_US
dc.contributor.authorSchork, Nicholasen_US
dc.contributor.authorSchottenfeld, Daviden_US
dc.contributor.authorLopatin, Dennis E.en_US
dc.contributor.authorLoesche, Walter J.en_US
dc.date.accessioned2010-04-01T15:52:44Z
dc.date.available2010-04-01T15:52:44Z
dc.date.issued1993-12en_US
dc.identifier.citationBretz, Walter A.; Eklund, Stephen A.; Radicchi, Ronald; Schork, Michael A.; Schork, Nicholas; Schottenfeld, David; Lopatin, Dennis E.; Loesche, Walter J. (1993). "The Use of a Rapid Enzymatic Assay in the Field for the Detection of Infections Associated with Adult Periodontitis." Journal of Public Health Dentistry 53(4): 235-240. <http://hdl.handle.net/2027.42/66375>en_US
dc.identifier.issn0022-4006en_US
dc.identifier.issn1752-7325en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/66375
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8258786&dopt=citationen_US
dc.description.abstractThere are few objective assays for studies of the epidemiology of periodontal diseases. The PerioScan™ is an assay capable of detecting three periodontal pathogens, namely T. denticola, P. gingivalis, and B. forsythus, which have been associated with adult periodontitis. The PerioScan™ was tested in a sample of 301 Brazilians. Clinical indices—bleeding, probing depth, gingival index, and periodontal index—were recorded from four sites in each subject. Subgingival plaque samples were collected from those sites and placed on the PerioScan™ card. Color results were scored in the field after 15 minutes. The plaque samples were screened with polyclonal antibodies for the three species by an ELISA system. The PerioScan™, when compared with the ELISA system, yields a sensitivity of 91 percent, specificity of 89 percent, and an accuracy of 90 percent. When the PerioScan™ was compared to clinical indices, there was a high sensitivity (at least 93%) and a low specificity (no less than 47%), with an accuracy of at least 61 percent.en_US
dc.format.extent974065 bytes
dc.format.extent3110 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1993 by the American Association of Public Health Dentistryen_US
dc.subject.otherPeriodontal Diseasesen_US
dc.subject.otherDiagnosisen_US
dc.subject.otherBANA Testen_US
dc.subject.otherT. Denticolaen_US
dc.subject.otherP. Gingivalisen_US
dc.subject.otherB. Forsythus.en_US
dc.titleThe Use of a Rapid Enzymatic Assay in the Field for the Detection of Infections Associated with Adult Periodontitisen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelDentistryen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumSchool of Dentistry and School of Public Health University of Michigan Ann Arbor, MIen_US
dc.identifier.pmid8258786en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/66375/1/j.1752-7325.1993.tb02710.x.pdf
dc.identifier.doi10.1111/j.1752-7325.1993.tb02710.xen_US
dc.identifier.sourceJournal of Public Health Dentistryen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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