Bkm sequences from the human X chromosome contain large clusters of GATA/GACA repeats
dc.contributor.author | Erickson, Robert P. | en_US |
dc.contributor.author | Ross, C. E. | en_US |
dc.contributor.author | Gorski, Jerome L. | en_US |
dc.contributor.author | Stalvey, John R. D. | en_US |
dc.contributor.author | Drumm, M. M. | en_US |
dc.date.accessioned | 2010-04-01T15:54:18Z | |
dc.date.available | 2010-04-01T15:54:18Z | |
dc.date.issued | 1988-07 | en_US |
dc.identifier.citation | ERICKSON, R. P.; ROSS, C. E.; GORSKI, J. L.; STALVEY, J. R. D.; DRUMM, M. M. (1988). "Bkm sequences from the human X chromosome contain large clusters of GATA/GACA repeats." Annals of Human Genetics 52(3): 167-176. <http://hdl.handle.net/2027.42/66402> | en_US |
dc.identifier.issn | 0003-4800 | en_US |
dc.identifier.issn | 1469-1809 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/66402 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3250328&dopt=citation | en_US |
dc.description.abstract | In order to determine whether the regional localizations of Bkm repeats detected on the human X chromosome consisted of typical GATA/GACA repeats, clones were isolated, mapped, and sequenced. Nine Bkm-hybridizing clones from Kunkel's fluorescent-activated, cell-sorted X-chromosome library were all unique. Five were mapped in detail with restriction enzymes and the Bkm-hybridizing segments were localized. Confirmation of X chromosomal homology was obtained for 2 of the clones and Bkm segments from these 2 clones were sequenced. Seventeen contiguous GATA repeats were found in each clone and the overall repeat arrangement showed relatively few differences from previously sequenced Bkm sequences. These are the first sequences of human Bkm repeats. The results, when compared with previously published results, suggest that there may be significant differences between the organization of Bkm repeats on the human X and on the human Y chromosome. | en_US |
dc.format.extent | 681076 bytes | |
dc.format.extent | 3110 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | 1988 University College London and Blackwell Publishing Ltd | en_US |
dc.title | Bkm sequences from the human X chromosome contain large clusters of GATA/GACA repeats | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Genetics | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | *Departments of Human Genetics, University of Michigan School of Medicine, Ann Arbor, Michigan 48109-0618 | en_US |
dc.contributor.affiliationum | †Departments of Pediatrics and Communicable Diseases, University of Michigan School of Medicine, Ann Arbor, Michigan 48109-0618 | en_US |
dc.identifier.pmid | 3250328 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/66402/1/j.1469-1809.1988.tb01094.x.pdf | |
dc.identifier.doi | 10.1111/j.1469-1809.1988.tb01094.x | en_US |
dc.identifier.source | Annals of Human Genetics | en_US |
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dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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