Does Seasonal Reproductive State Affect the Neuroendocrine Response of the Ewe to a Long-Day Pattern of Melatonin?
dc.contributor.author | Woodfill, Celia J. I. | en_US |
dc.contributor.author | Wayne, Nancy L. | en_US |
dc.contributor.author | Karsch, Fred J. | en_US |
dc.date.accessioned | 2010-04-13T18:41:37Z | |
dc.date.available | 2010-04-13T18:41:37Z | |
dc.date.issued | 1992 | en_US |
dc.identifier.citation | Woodfill, Celia J. I.; Wayne, Nancy; Karsch, Fred (1992). "Does Seasonal Reproductive State Affect the Neuroendocrine Response of the Ewe to a Long-Day Pattern of Melatonin?." Journal of Biological Rhythms 7(1): 1-11. <http://hdl.handle.net/2027.42/66625> | en_US |
dc.identifier.issn | 0748-7304 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/66625 | |
dc.description.abstract | This study examined whether or not the reproductive response of female sheep to photoperiod varies with seasonal reproductive state. The specific objective was to test the hypothesis that the reproductive response to a long-day pattern of melatonin varies with the reproductive state of the ewe. The response examined was the synchronization of reproductive neuroendocrine induction (rise in serum luteinizing hormone, or LH) following nocturnal infusion of melatonin into pinealectomized ewes for 35 consecutive nights. This infusion restored a pattern of circulating melatonin similar to that in pineal-intact ewes maintained in a long photoperiod (LD 16:8). The ewes had been pinealectomized and without melatonin replacement for 16-25 months prior to the study. They were in differing reproductive states at the start of the infusion, as their endogenous reproductive rhythm had become desynchronized among individuals and with respect to time of year. Noninfused pinealectomized ewes served as controls. Regardless of the reproductive state at the start of the 35-day infusion of the long-day pattern of melatonin, all treated ewes exhibited the same reproductive neuroendocrine response after the infusion was ended. This consisted of a synchronized rise in LH some 6-8 weeks after the infusion was terminated, the maintenance of a high level of serum LH for some 15 weeks, and a subsequent precipitous fall in LH to a very low level. These results provide evidence that a long-day pattern of melatonin can synchronize reproductive neuroendocrine induction in the ewe, regardless of reproductive condition, and thus do not support the hypothesis that this response differs with seasonal reproductive state. | en_US |
dc.format.extent | 3108 bytes | |
dc.format.extent | 641678 bytes | |
dc.format.mimetype | text/plain | |
dc.format.mimetype | application/pdf | |
dc.publisher | Sage Publications | en_US |
dc.subject.other | Circannual Rhythm | en_US |
dc.subject.other | Photoperiod | en_US |
dc.subject.other | Photoperiodic History | en_US |
dc.subject.other | Photoperiodism | en_US |
dc.subject.other | Pineal Gland | en_US |
dc.subject.other | Seasonal Reproduction | en_US |
dc.subject.other | Sheep | en_US |
dc.subject.other | Luteinizing Hormone | en_US |
dc.title | Does Seasonal Reproductive State Affect the Neuroendocrine Response of the Ewe to a Long-Day Pattern of Melatonin? | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Complementary and Alternative Medicine | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Reproductive Sciences Program and Department of Physiology, University of Michigan, Ann Arbor, Michigan 48109-0404 | en_US |
dc.contributor.affiliationum | Reproductive Sciences Program and Department of Physiology, University of Michigan, Ann Arbor, Michigan 48109-0404 | en_US |
dc.contributor.affiliationum | Reproductive Sciences Program and Department of Physiology, University of Michigan, Ann Arbor, Michigan 48109-0404 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/66625/2/10.1177_074873049200700101.pdf | |
dc.identifier.doi | 10.1177/074873049200700101 | en_US |
dc.identifier.source | Journal of Biological Rhythms | en_US |
dc.identifier.citedreference | Bittman, E.L., R.J. Dempsey, and F.J. Karsch (1983a) Pineal melatonin secretion drives the reproductive response to daylength in the ewe. Endocnnology 113: 2276-2283. | en_US |
dc.identifier.citedreference | Bittman, E.L., F.J. Karsch, and J.W. Hopkins (1983b) Role of the pineal gland in ovine photopenodism: Regulation of seasonal breeding and negative feedback effects of estradiol upon luteinizing hormone secretion. Endocrinology 113: 329-336. | en_US |
dc.identifier.citedreference | Brown, M.B., F.J. Karsch, and B.M. Malpaux (1988) An algorithm to identify changes in hormone patterns. Proc. Symp. Interface Comput. Sci. Stat. 20: 54-59. | en_US |
dc.identifier.citedreference | Dempsey, R.J., J. Hopkins, E.L. Bittman, and G.W. Kindt (1982) Total pinealectomy by an occipital parasagittal approach in sheep. Surg. Neurol. 18: 377-380. | en_US |
dc.identifier.citedreference | Duston, J., and N. Bromage (1988) The entrainment and gating of the endogenous circannual rhythm of reproduction in the female rainbow trout (Salmo gairdneri J. Comp. Physiol. A 164: 259-268. | en_US |
dc.identifier.citedreference | Ebling, F.J.P., R.I. Wood, J.M. Suttie, T.E. Adel, and D.L. Foster (1989) Prenatal photoperiod influences neonatal prolactin secretion in the sheep. Endocrinology 125: 384-391. | en_US |
dc.identifier.citedreference | English, J., A.L. Poulton, J. Arendt, and A.M. Symons (1986) A comparison of the efficiency of melatonin treatments in advancing oestrus in ewes. J. Reprod. Fertil. 77: 321-327. | en_US |
dc.identifier.citedreference | Farner, D.S. (1985) Annual rhythms. Ann. Rev. Physiol. 47. 65-82. | en_US |
dc.identifier.citedreference | Foster, D.L., F.J.P. Ebling, L.E. Claypool, and C.J.I. Woodfill (1988) Cessation of long day melatonin rhythms time puberty in a short day breeder. Endocrinology 123: 1636-1641. | en_US |
dc.identifier.citedreference | Gwinner, E. (1971) A comparative study of circannual rhythms m warblers. In Biochronometry, M. Menaker, ed., pp. 405-427, National Academy of Sciences, Washington, DC. | en_US |
dc.identifier.citedreference | Gwinner, E. (1973) Circannual rhythms in birds: Their interaction with circadian rhythms and environmental photoperiod. J. Reprod. Fertil. Suppl. 19: 51-65. | en_US |
dc.identifier.citedreference | Gwinner, E. (1986) Circannual Rhythms, Spnnger-Verlag, New York. | en_US |
dc.identifier.citedreference | Gwinner, E., J.P. Dittami, and H.J.A. Veldhuis (1988) The seasonal development of photopenodic responsiveness in an equatorial migrant, the garden warbler Sylvia borin. J. Comp. Physiol. A 162: 389-396. | en_US |
dc.identifier.citedreference | Hastings, M.H., A.P. Walker, J.B. Powers, J. Hutchison, E.A. Steel, and J. Herbert (1989) Differential effects of photopenodic history on the responses of gonadotrophins and prolactin to intermediate daylengths in the male Syrian hamster. J. Biol. Rhythms 4: 335-350. | en_US |
dc.identifier.citedreference | Hauger, R.L., F.J. Karsch, and D.L. Foster (1977) A new concept for control of the estrous cycle of the ewe based on the temporal relationships between luteinizing hormone, estradiol and progesterone in peripheral serum and evidence that progesterone inhibits tonic LH secretion. Endocrinology 101. 807-817 | en_US |
dc.identifier.citedreference | Hoffmann, K., and H. Illnerova (1986) Photopenodic effects in the Djunganan hamster. Neuroendocnnology 43: 317-321. | en_US |
dc.identifier.citedreference | Hoffmann, K., H. Illnerová, and J. Vaněček (1986) Change in duration of the nighttime melatonin peak may be a signal driving photoperiodic responses in the Djungarian hamster (Phodopus sungorus. Neurosci. Lett. 67: 68-72. | en_US |
dc.identifier.citedreference | Horton, T.H. (1984) Growth and reproductive development of male Microtus montanus is affected by the prenatal photoperiod. Biol. Reprod. 31: 499-504. | en_US |
dc.identifier.citedreference | Jackson, G.L., M. Gibson, and D. Kuehl (1988) Photoperiodic disruption of photorefractonness in the ewe. Biol. Reprod. 38: 127-134. | en_US |
dc.identifier.citedreference | Jackson, G.L., H.T. Jansen, D.E. Kuehl, and R.D. Shanks (1989) Time of the sidereal year affects responsiveness to the phase-resetting effects of photoperiod in the ewe. J. Reprod. Fertil. 85: 221-227. | en_US |
dc.identifier.citedreference | Karsch, F.J., E.L. Bittman, D.L. Foster, R.L. Goodman, S.J. Legan, and J.E. Robinson (1984) Neuroendocrine basis of seasonal reproduction. Rec. Prog. Horm. Res. 40: 185-232. | en_US |
dc.identifier.citedreference | Karsch, F.J., D.J. Dierschke, R.F. Weick, T. Yamaji, J. Hotchkiss, and E. Knobil (1973) Positive and negative feedback control by estrogen of luteinizing hormone secretion in the rhesus monkey. Endocrinology 92: 799-804. | en_US |
dc.identifier.citedreference | Karsch, F.J., and D.L. Foster (1975) Sexual differentiation of the mechanism controlling the preovulatory discharge of luteinizing hormone in sheep. Endocnnology 97: 373-379. | en_US |
dc.identifier.citedreference | Karsch, F.J., J.E. Robinson, C.J.I. Woodfill, and M.B. Brown (1989) Circannual cycles of luteinizing hormone and prolactin secretion in ewes during prolonged exposure to a fixed photoperiod: Evidence for an endogenous reproductive rhythm. Biol. Reprod. 41: 1034-1046. | en_US |
dc.identifier.citedreference | Kotz, S., and N. L. Johnson, eds. (1982) Encyclopedia of Statistical Sciences, Wiley, New York. | en_US |
dc.identifier.citedreference | Lee, T.M., and I. Zucker (1988) Vole infant development is influenced perinatally by maternal photopenodic history. Am. J. Physiol. 255: R831-R838. | en_US |
dc.identifier.citedreference | Lee, T.M., and I. Zucker (1991) Suprachiasmatic nucleus and photic entrainment of circannual rhythms in ground squirrels. J. Biol Rhythms 6: 315-330. | en_US |
dc.identifier.citedreference | Legan, S.J., and F.J. Karsch (1979) Neuroendocnne regulation of the estrous cycle and seasonal breeding in the ewe. Biol Reprod. 20: 74-85. | en_US |
dc.identifier.citedreference | Legan, S.J., F.J. Karsch, and D.L. Foster (1977) The endocrine control of seasonal reproductive function in the ewe: A marked change in response to the negative feedback action of estradiol on luteinizing hormone secretion. Endocrinology 101. 818-824. | en_US |
dc.identifier.citedreference | Malpaux, B., J.E. Robinson, M.B. Brown, and F.J. Karsch (1987) Reproductive refractoriness of the ewe to inductive photopenod is not caused by inappropriate secretion of melatonin Biol. Reprod 36: 1333-1341. | en_US |
dc.identifier.citedreference | Malpaux, B., J.E. Robisnon, N.L. Wayne, and F.J. Karsch (1989) Regulation of the onset of the breeding season of the ewe: Importance of long days and of an endogenous reproductive rhythm. J Endocnnology 122: 269-278 | en_US |
dc.identifier.citedreference | Niswender, G.D., A.R. Midgley, and L.E. Reichert (1968) Radioimmunologic studies with munne, bovine, ovine, and porcine luteinizing hormone. In Gonadotropins, E Rosenberg, ed, pp 229-306, Geron-X, Los Altos, CA. | en_US |
dc.identifier.citedreference | Niswender, G.D., L.E. Reichert, A.R. Midgley, JR., and A.V. Nalbandov (1969) Radioimmunoassay for bovine and ovine luteinizing hormone Endocrinology 84. 1166-1173 | en_US |
dc.identifier.citedreference | Robinson, J.E., and B.K. Follett (1982) Photoperiodism in Japanese quail: The termination of seasonal breeding by photorefractonness. Proc Roy. Soc. Lond B. 215: 95-116. | en_US |
dc.identifier.citedreference | Robinson, J.E., and F.J. Karsch (1987) Photopenodic history and a changing melatonin pattern can determine the neuroendocnne response of the ewe to daylength. J. Reprod. Fertil, 80. 159-165. | en_US |
dc.identifier.citedreference | Roche, J.F., and P.J. Dziuk (1969) A technique for pinealectomy of the ewe. Am. J. Vet. Res. 30: 2031-2035. | en_US |
dc.identifier.citedreference | Wayne, N.L., B.M. Malpaux, and F.J. Karsch (1988) How does melatonin code for day length in the ewe: Duration of nocturnal melatonin release or coincidence of melatonin with a light-entrained sensitive penod? Biol. Reprod. 39: 66-75 | en_US |
dc.identifier.citedreference | Wayne, N.L., B.M. Malpaux, and F.J. Karsch (1990) Photopenodic requirements for timing onset and duration of the breeding season in the ewe. J. Comp. Physiol. 166: 835-842. | en_US |
dc.identifier.citedreference | Woodfill, C.J.I. (1990) Photoperiodic Synchronization of the Annual Reproductive Rhythm of the Ewe, Ph D dissertation, University of Michigan. | en_US |
dc.identifier.citedreference | Woodfill, C.J.I., J.E. Robinson, B. Malpaux, and F.J. Karsch (1991) Synchronization of the circannual reproductive rhythm of the ewe by discrete photoperiodic signals Biol. Reprod. 45: 110-121 | en_US |
dc.identifier.citedreference | Zar, J.H. (1984) Biostatistical Analysis, Prentice-Hall, Englewood Cliffs, NJ. | en_US |
dc.identifier.citedreference | Zucker I., T.M. Lee, and J. Dark (1991) The suprachiasmatic nucleus and annual rhythms of mammals. In Suprachiasmatic Nucleus: The Mind's Clock, D. Klein, S. Reppert, and R. Moore, eds., pp. 246-259, Oxford University Press, New York. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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