Cytotoxicity of Experimental Casting Alloys Evaluated by Cell Culture Tests
dc.contributor.author | Craig, Robert G. | en_US |
dc.contributor.author | Hanks, Carl T. | en_US |
dc.date.accessioned | 2010-04-13T19:28:27Z | |
dc.date.available | 2010-04-13T19:28:27Z | |
dc.date.issued | 1990 | en_US |
dc.identifier.citation | Craig, R.G.; Hanks, C.T. (1990). "Cytotoxicity of Experimental Casting Alloys Evaluated by Cell Culture Tests." Journal of Dental Research 8(69): 1539-1542. <http://hdl.handle.net/2027.42/67442> | en_US |
dc.identifier.issn | 0022-0345 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/67442 | |
dc.description.abstract | The cytotoxicity of a series of 29 experimental alloys and six pure metals was determined with cell culture techniques and succinic dehydrogenase histochemistry. The width of any ring of inhibition, optical density of the histochemically stained cells, and a visual ranking of the intensity of the blue color of the stained cells were compared for determination of cytotoxicity. Twenty-four of the 35 metals and alloys (-70%) had the same rankings by the three methods. Of the pure metals, Au, Pd, and Ti were the least cytotoxic, followed by Ag, then Ni, and finally, Cu. Single-phase alloys with moderately high Cu and without high Pd and Au concentrations had high cytotoxicity, as did multiphase alloys, even when they were high in Au and Ag. High Pd was more effective in maintaining the biocompatibility of alloys containing Cu than was Au. Single-phase alloys with compositions typical of those to be used for porcelain-fused-to-metal restorations showed good biocompatibility, as did those base metal alloys that formed adherent oxide surface layers. | en_US |
dc.format.extent | 3108 bytes | |
dc.format.extent | 520036 bytes | |
dc.format.mimetype | text/plain | |
dc.format.mimetype | application/pdf | |
dc.publisher | SAGE Publications | en_US |
dc.title | Cytotoxicity of Experimental Casting Alloys Evaluated by Cell Culture Tests | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Dentistry | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | School of Dentistry, University of Michigan, Ann Arbor, MI 48109-1078 | en_US |
dc.contributor.affiliationum | School of Dentistry, University of Michigan, Ann Arbor, MI 48109-1078 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/67442/2/10.1177_00220345900690081801.pdf | |
dc.identifier.doi | 10.1177/00220345900690081801 | en_US |
dc.identifier.citedreference | Bumgardner, J.D.; Lucas, L.C.; and Tilden, A.B. (1989): Cell Culture Analyses of Aluminum-Bronze and Aluminum-Brass Alloys, J Dent Res 68:322, Abst. No. 1123. | en_US |
dc.identifier.citedreference | Craig, R.G. and Hanks, C.T. (1988): Reaction of Fibroblasts to Various Dental Casting Alloys, J Oral Pathol 17:341-347. | en_US |
dc.identifier.citedreference | Lemons, J.E.; Lucas, L.C.; Henson, P.; and Hill, C. (1988): Biocompatibility of Copper Base Alloys, J Dent Res 67:262, Abst. No. 1196. | en_US |
dc.identifier.citedreference | Meyer, J.M.; Craig, R.G.; Schmalz, G.; and Reclaru, L. (1989): Corrosion Resistance and Biocompatibility of Some Low Gold Dental Casting Alloys, European Dental Materials Conference, University of Glasgow, Scotland, Sept. 8. | en_US |
dc.identifier.citedreference | Pearse, A.G.E. (1972): Histochemistry; Theoretical and Applied, Vol. 2, 3rd ed. Baltimore: Williams and Wilkins Co., p. 1343. | en_US |
dc.identifier.citedreference | Wataha, J.C.; Craig, R.G.; and Hanks, C.T. (1989): Analysis of Culture Medium for Elements Dissolved from Casting Alloys, J Dent Res 68:322, Abst. No. 1122. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.