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Cytogenetic Studies of Normal and Cleft-Palate Epitheliums in Mice

dc.contributor.authorNasjleti, Carlos E.en_US
dc.contributor.authorSpencer, H. H. (Herbert H.)en_US
dc.contributor.authorBlankenship, Johnen_US
dc.contributor.authorWalden, Jamesen_US
dc.date.accessioned2010-04-13T20:08:06Z
dc.date.available2010-04-13T20:08:06Z
dc.date.issued1969en_US
dc.identifier.citationNasjleti, Carlos; Spencer, Herbert; Blankenship, John; Walden, James (1969). "Cytogenetic Studies of Normal and Cleft-Palate Epitheliums in Mice." Journal of Dental Research 4(48): 590-594. <http://hdl.handle.net/2027.42/68120>en_US
dc.identifier.issn0022-0345en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/68120
dc.description.abstractThis study investigated teratogenic activity on a cellular level through analysis of the cytogenetic complex in cleft-palate epithelial cells from the progenies of mice treated with cortisone. Analysis showed no detectable aberration from a normal chromosomal complement.en_US
dc.format.extent3108 bytes
dc.format.extent654249 bytes
dc.format.mimetypetext/plain
dc.format.mimetypeapplication/pdf
dc.publisherSAGE Publicationsen_US
dc.titleCytogenetic Studies of Normal and Cleft-Palate Epitheliums in Miceen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelDentistryen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumVeterans Administration Hospital and the University of Michigan, Ann Arbor, Michigan 48105en_US
dc.contributor.affiliationumVeterans Administration Hospital and the University of Michigan, Ann Arbor, Michigan 48105en_US
dc.contributor.affiliationumVeterans Administration Hospital and the University of Michigan, Ann Arbor, Michigan 48105en_US
dc.contributor.affiliationumVeterans Administration Hospital and the University of Michigan, Ann Arbor, Michigan 48105en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/68120/2/10.1177_00220345690480041601.pdf
dc.identifier.doi10.1177/00220345690480041601en_US
dc.identifier.citedreferenceGreene, J.C. ; Vermillion, J.R.; Hay, S.; Gibbens, S.F.; and Kerschbaum, S.: Epidemiologic Study of Cleft Lip and Cleft Palate in Four States, JADA 68:389-402, 1964.en_US
dc.identifier.citedreferenceMICHIGAN CRIPPLED CHILDREN'S COMMISSION : Annual Report, 1959.en_US
dc.identifier.citedreferenceGRopp, A. ; Jussen, A.; and Odunjo, F.: Near-Triploid Chromosome Constitution in Epithelial-Cell Cultures of Palatal Mucosa from a Case of Cleft Palate, Lancet 1: 1167, 1964.en_US
dc.identifier.citedreferenceSou Kup, S., and Warkany, J.: Chromosomes in Cleft-Palate Tissues, Lancet 1: 492-493, 1966.en_US
dc.identifier.citedreferenceJackson, J.F. : Chromosomes in Cleft-Palate Tissues, Lancet 1:1156, 1966.en_US
dc.identifier.citedreferenceMurphy, J.W., and Reisman, L.E.: Chromosomes in Cleft-Palate Tissues, Lancet 11:228-229, 1966.en_US
dc.identifier.citedreferenceNasjleti, C.E. ; Walden, J.M.; and Spencer, H.H.: Polyploidization and Aberration of Human Chromosomes Induced In Vitro and In Vivo with Ionizing Radiations, J Nucl Med 7:159-176, 1966.en_US
dc.identifier.citedreferenceNasjleti, C.E., and Spencer, H.H.: Chromosome Polyploidization in Human Leukocytes Induced by Radiation, Ann NY Acad Sci 155:748-758, 1968.en_US
dc.identifier.citedreferenceNasjleti, C.E. ; Walden, J.M.; and Spencer, H.H.: Polyploidy and Endoreduplication Induced In Vivo and In Vitro in Human Leukocytes with N,N'-bis-(3-bromopropionyl) Piperazine (A-8103), Cancer Res 25:275-285, 1965.en_US
dc.identifier.citedreferenceNasjleti, C.E., and Spencer, H.H.: Chromosome Damage and Polyploidization Induced in Human Peripheral Leukocytes In Vivo and In Vitro with Nitrogen Mustard, 6-Mercaptopurine, and A-649, Cancer Res 26:2437-2443, 1966.en_US
dc.identifier.citedreferenceNasjleti, C.E. ; Avery, J.K.; Spencer, H.H.; and Walden, J.M.: Tritiated Cortisone Distribution and Induced Cleft Palate in Mice, J Oral Ther 4:71-83, 1967.en_US
dc.identifier.citedreferenceMajor, M.W.: A Study of the Effect of Cortisone on the Chromosomes of Somatic Cells of the Nineteen-Day Fetal Mouse, unpublished MS thesis, University of Michigan School of Dentistry, 1964.en_US
dc.identifier.citedreferenceIngalls, T.H. ; Ingenito, E.F.; and Curley, J.J.: Acquired Chromosomal Anomalies Induced in Mice by Injection of a Teratogen in Pregnancy, Science 141: 810-812, 1963.en_US
dc.identifier.citedreferenceMuramoto, H. ; Aya, T.; and Sasaki, M.: Chromosome Study of Patients with Cleft Lip and Cleft Palate Based on Lesion Biopsies in Culture, Jap J Hum Genet 11: 31-35, 1966.en_US
dc.identifier.citedreferenceNasjleti, C.E., and Spencer, H.H.: Unpublished data.en_US
dc.identifier.citedreferenceBarski, G.: "Cytogenic Alterations in Mixed Cultures of Mammalian Somatic Cells In Vitro," in Harris, R.J.C. (ed): Cytogenetics of Cells in Culture, Vol. 3, New York and London: Academic Press, 1964.en_US
dc.identifier.citedreferenceSubrt, I.; Cervenka, J.; and Krecek, M.: Cytogenetic Study of Cleft Lip and Palate, Cleft Palate J 3:362-367, 1966.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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