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Critical Limb Ischemia in Patients with End-Stage Renal Disease: Do Long-Term Results Justify An Aggressive Surgical Approach?

dc.contributor.authorDovgan, Peteren_US
dc.contributor.authorShepard, Alexanderen_US
dc.contributor.authorNypaver, Timothyen_US
dc.date.accessioned2010-04-14T13:54:18Z
dc.date.available2010-04-14T13:54:18Z
dc.date.issued1999en_US
dc.identifier.citationDovgan, Peter; Shepard, Alexander; Nypaver, Timothy (1999). "Critical Limb Ischemia in Patients with End-Stage Renal Disease: Do Long-Term Results Justify An Aggressive Surgical Approach?." Perspectives in Vascular Surgery and Endovascular Therapy 12(1): 81-92. <http://hdl.handle.net/2027.42/68696>en_US
dc.identifier.issn1531-0035en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/68696
dc.description.abstractEnd-stage renal disease (ESRD) patients probably represent the most difficult group of patients vascular surgeons are called upon to treat for critical limb ischemia. Advanced lower extremity arterial occlusive disease and frequent comorbidities make infrainguinal arterial bypass grafting (IABG) in this population both technically and medically challenging. Results of IABG are far inferior to those in non-ESRD patients. The greatest limitation to limb salvage appears to be progressive tissue necrosis and infection despite a patent bypass graft, a problem nearly unique to ESRD. Clinical predictors of outcome for IABG in this population have not been well established. The site and extent of tissue loss, the presence of associated infection, and the degree of pedal level occlusive disease have been identified as potentially important predictors. Improving outcome for ESRD patients with critical limb ischemia requires the establishment of firm guidelines for IABG to avoid futile and risky attempts at bypass in individuals better served by primary amputation.en_US
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dc.format.extent812646 bytes
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dc.publisherSage Publicationsen_US
dc.subject.otherEnd-stage Renal Diseaseen_US
dc.subject.otherArterialen_US
dc.subject.otherInfrainguinalen_US
dc.subject.otherBypassen_US
dc.subject.otherRenal Diseaseen_US
dc.titleCritical Limb Ischemia in Patients with End-Stage Renal Disease: Do Long-Term Results Justify An Aggressive Surgical Approach?en_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialitiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan Medical Schoolen_US
dc.contributor.affiliationotherDivision of Vascular Surgery, Department of Surgery, Henry Ford Hospital, Detroit, MIen_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/68696/2/10.1177_153100359901200114.pdf
dc.identifier.doi10.1177/153100359901200114en_US
dc.identifier.sourcePerspectives in Vascular Surgery and Endovascular Therapyen_US
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dc.owningcollnameInterdisciplinary and Peer-Reviewed


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