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Magnetically modulated optical nanoprobes
dc.contributor.authorAnker, Jeffrey N.en_US
dc.contributor.authorKopelman, Raoulen_US
dc.date.accessioned2010-05-06T20:56:00Z
dc.date.available2010-05-06T20:56:00Z
dc.date.issued2003-02-17en_US
dc.identifier.citationAnker, Jeffrey N.; Kopelman, Raoul (2003). "Magnetically modulated optical nanoprobes." Applied Physics Letters 82(7): 1102-1104. <http://hdl.handle.net/2027.42/69653>en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/69653
dc.description.abstractWe have developed magnetically modulated optical nanoprobes (MagMOONs) to magnetically modulate the signal from fluorescent probes and thus separate it from autofluorescence, electronic offsets, and other background signals. These micro- and nanosized particles emit fluorescence signals, indicating chemical concentrations, and blink in response to rotating magnetic fields. Demodulating the signal dramatically enhances the probe’s signal to background ratio. The probes and methods promise to improve immunoassays, intracellular chemical sensing, and fundamental biochemical research. © 2003 American Institute of Physics.en_US
dc.format.extent3102 bytes
dc.format.extent132635 bytes
dc.format.mimetypetext/plain
dc.format.mimetypeapplication/pdf
dc.publisherThe American Institute of Physicsen_US
dc.rights© The American Institute of Physicsen_US
dc.titleMagnetically modulated optical nanoprobesen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPhysicsen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumThe University of Michigan Chemistry Department, Ann Arbor, Michigan 48109-1055en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/69653/2/APPLAB-82-7-1102-1.pdf
dc.identifier.doi10.1063/1.1544435en_US
dc.identifier.sourceApplied Physics Lettersen_US
dc.identifier.citedreferenceT. A. Byassee, W. C. W. Chan, and S. M. Nie, Anal. Chem. ANCHAM72, 5606 (2000).en_US
dc.identifier.citedreferenceR. Kopelman and W. H. Tan, Science SCIEAS262, 1382 (1993).en_US
dc.identifier.citedreferenceE. Monson, M. Brasuel, and M. A. Philbert, Biomedical Photonic Handbook, edited by T. Vo-Dinh (in press).en_US
dc.identifier.citedreferenceR. P. Haugland, Handbook of Fluorescent Probes and Research Chemicals, sixth ed. (Molecular Probes, Inc., Eugene OR., 1996).en_US
dc.identifier.citedreferenceK. R. Rogers, Mol. Biotechnol. MLBOEO14, 109 (2000).en_US
dc.identifier.citedreferenceZ. Darzynkiewicz, E. Bedner, X. Li, W. Gorczyca, and M. R. Melamed, Exp. Cell Res. ECREAL249, 1 (1999).en_US
dc.identifier.citedreferenceV. Subramaniam, A. Gafni, and D. G. Steel, IEEE J. Sel. Top. Quantum Electron. IJSQEN2, 1107 (1996).en_US
dc.identifier.citedreferenceX. W. Zhuang, H. Kim, M. J. B. Pereira, H. P. Babcock, N. G. Walter, and S. Chu, Science SCIEAS296, 1473 (2002).en_US
dc.identifier.citedreferenceP. A. Valberg and J. P. Butler, Biophys. J. BIOJAU52, 537 (1987).en_US
dc.identifier.citedreferenceSee EPAPS Document No. E-APPLAB-82-028307 for two videos of MagMOONs’ synchronously rotating and blinking. A direct link to this document may be found in the online article’s HTML reference section. The document may also be reached via the EPAPS homepage (http://www.aip.org/pubservs/epaps.html) or from ftp.aip.org in the directory /epaps/. See the EPAPS homepage for more information.en_US
dc.identifier.citedreferenceJ. N. Anker, C. Behrend, and R. Kopelman, J. Appl. Phys. (in press).en_US
dc.identifier.citedreferenceF. H. C. Crick and A. F. W. Hughes, Exp. Cell. Res. ECREAL1, 37 (1950).en_US
dc.identifier.citedreferenceM. Keller, J. Schilling, and E. Sackmann, Rev. Sci. Instrum. RSINAK72, 3626 (2001).en_US
dc.identifier.citedreferenceK. Braeckmans, S. C. De Smedt, M. Leblans, R. Pauwels, and J. Demeester, Nature Reviews Drug Discovery ZZZZZZ1, 447 (2002).en_US
dc.owningcollnamePhysics, Department of


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