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Applications of Metallic Shadow‐Casting to Microscopy
dc.contributor.authorWilliams, Robley C. (Robley Cook)en_US
dc.contributor.authorWyckoff, Ralph W. G.en_US
dc.date.accessioned2010-05-06T22:27:57Z
dc.date.available2010-05-06T22:27:57Z
dc.date.issued1946-01en_US
dc.identifier.citationWilliams, Robley C.; Wyckoff, Ralph W. G. (1946). "Applications of Metallic Shadow‐Casting to Microscopy." Journal of Applied Physics 17(1): 23-33. <http://hdl.handle.net/2027.42/70631>en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/70631
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=20276719&dopt=citationen_US
dc.description.abstractThe factors which determine image contrast in optical and electron micrographs are discussed in relation to a new metal shadow‐casting technique whereby the contrast of images is greatly increased by depositing obliquely a thin film of metal on the microscope preparations. Further advantages of the use of shadow‐casting are described, and an estimate is made of the lower limit of size of objects which should be observable by shadow‐casting. Examples are given and illustrations are shown of the applications of this technique to the electron micrography of particles of macromolecular dimensions, of replicas of such particles, and of surface replicas prepared in several ways.en_US
dc.format.extent3102 bytes
dc.format.extent2403815 bytes
dc.format.mimetypetext/plain
dc.format.mimetypeapplication/pdf
dc.publisherThe American Institute of Physicsen_US
dc.rights© The American Institute of Physicsen_US
dc.titleApplications of Metallic Shadow‐Casting to Microscopyen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPhysicsen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumUniversity of Michigan, Ann Arbor, Michiganen_US
dc.identifier.pmid20276719en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/70631/2/JAPIAU-17-1-23-1.pdf
dc.identifier.doi10.1063/1.1707630en_US
dc.identifier.sourceJournal of Applied Physicsen_US
dc.identifier.citedreferenceFrom the Department of Physics, University of Michigan.en_US
dc.identifier.citedreferenceThis research was supported in part by the Evaporated Metals Films Corporation, Ithaca, New York.en_US
dc.identifier.citedreferenceFormvar 15–95 is a polyvinyl formal supplied by the Shawinigan Products Corporation, New York, New York.en_US
dc.identifier.citedreferenceV. J. Schaefer and D. Harker, J. App. Phys. 13, 427 (1942).en_US
dc.identifier.citedreferenceR. D. Heidenreich and V. G. Peck, J. App. Phys. 14, 23 (1943); R. D. Heidenreich, 14, 312 (1943).en_US
dc.identifier.citedreferenceR. C. Williams and R. W. G. Wyckoff, J. App. Phys. 15, 712 (1944).en_US
dc.identifier.citedreferenceR. C. Williams and R. W. G. Wyckoff, Proc. Soc. Exp. Biol. Med. 59, 265 (1945).en_US
dc.identifier.citedreferenceR. C. Williams and R. W. G. Wyckoff, Science 101, 594 (1945).en_US
dc.identifier.citedreferenceH. O. Müller, Kolloid Zeits. 99, 6 (1942).en_US
dc.identifier.citedreferenceSee R. D. Heidenreich and L. A. Matheson, J. App. Phys. 15, 423 (1944), for references.en_US
dc.identifier.citedreferenceFaxfilm, R. D. McDill, Cleveland, Ohio.en_US
dc.identifier.citedreferenceH. Mahl, Zeits. f. Tech. Physik 21, 17 (1940); 22, 33 (1941); Metalwirtschaft 19, 1082 (1940); V. K. Zworykin and E. G. Ramberg, J. App. Phys. 12, 692 (1941); V. J. Schaefer and D. Harker, see reference 4; R. D. Heidenreich and V. G. Peck, see reference 5.en_US
dc.identifier.citedreferenceR. D. Heidenreich, see reference 5.en_US
dc.identifier.citedreferenceAll the electron micrographs of this paper are from negative prints of intermediate contact positives on lantern slide emulsion. The scale of magnification in each instance is indicated by the one micron scale underneath the photograph.en_US
dc.identifier.citedreferenceL. Thomassen, R. C. Williams, and R. W. G. Wyckoff, Rev. Sci. Inst. 16, 155 (1945).en_US
dc.identifier.citedreferenceR. C. Williams and R. W. G. Wyckoff, Proc. Soc. Exp. Biol. Med. 58, 265 (1945).en_US
dc.identifier.citedreferenceR. C. Williams and R. W. G. Wyckoff, Nature 156, 68 (1945).en_US
dc.identifier.citedreferenceW. C. Price, R. C. Williams, and R. W. G. Wyckoff, Science 102, 277 (1945); Arch. Biochem. In press.en_US
dc.owningcollnamePhysics, Department of


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