Show simple item record

The surgical management of hyperparathyroidism and endocrine disease of the pancreas in the multiple endocrine neoplasia type 1 patient

dc.contributor.authorThompson, N. W.en_US
dc.date.accessioned2010-06-01T18:17:28Z
dc.date.available2010-06-01T18:17:28Z
dc.date.issued1995-09en_US
dc.identifier.citationTHOMPSON, N. W. (1995). "The surgical management of hyperparathyroidism and endocrine disease of the pancreas in the multiple endocrine neoplasia type 1 patient." Journal of Internal Medicine 238(3): 269-280. <http://hdl.handle.net/2027.42/71501>en_US
dc.identifier.issn0954-6820en_US
dc.identifier.issn1365-2796en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/71501
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7673858&dopt=citationen_US
dc.description.abstractThe surgical management of multiple endocrine neoplasia type 1 (MEN1) parathyroid disease and involvement of the endocrine pancreas remains controversial. Hyperparathyroidism, usually the first clinical manifestation of the syndrome, requires surgical treatment in nearly all patients. We favour a subtotal parathyroidectomy and cervical thymectomy rather than a total parathyroidectomy and autotransplant because of good long-term results and the absence of permanent hypoparathyroidism. The results of treating 34 MEN1 patients during a 20-year period are reported. The most common functional pancreatic or duodenal tumours in MEN1 patients are gastrinomas and insulinomas. In addition to the management of functional syndromes, another major concern is the malignant potential of the neuroendocrine tumours that frequently develop. Our surgical management of gastrinomas and the ZES has evolved over a period of 15 years. We have found that distal pancreatectomy, enucleation of any neoplasms in the head, and duodenotomy and excision of any neuroendocrine tumours (gastrinomas) combined with a regional node dissection are effective in the majority of patients. The results of treating 21 MEN1 patients with ZES are reported.en_US
dc.format.extent1740748 bytes
dc.format.extent3109 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.publisherBlackwell Publishing Ltden_US
dc.rights1995 Blackwell Publishing Ltden_US
dc.subject.otherMEN1en_US
dc.subject.otherHyperparathyroidism ZESen_US
dc.subject.otherGastrinomasen_US
dc.subject.otherNeuroendocrine Tumorsen_US
dc.titleThe surgical management of hyperparathyroidism and endocrine disease of the pancreas in the multiple endocrine neoplasia type 1 patienten_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialtiesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDivision of Endocrine Surgery, University of Michigan, Department of Surgery, Ann Arbor, Michigan, USAen_US
dc.identifier.pmid7673858en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/71501/1/j.1365-2796.1995.tb00934.x.pdf
dc.identifier.doi10.1111/j.1365-2796.1995.tb00934.xen_US
dc.identifier.sourceJournal of Internal Medicineen_US
dc.identifier.citedreferenceAllo M., Thompson NW. Hyperparathyroidism as a part of the MEN I Syndrome. In: Kaplan EL, ed. Surgery of the Thyroid and Parathyroid Glands. Clinical Surgery International. Churchill Livingston, 1983: 177 – 92.en_US
dc.identifier.citedreferenceBlock MA. Familial hyperparathyroidism and hyperparathyroidism associated with multiple endocrine neoplasia syndrome. In: Cady B., Rossi RL, eds. Surgery of the Thyroid and Parathyroid Glands, 3rd edn. Philadelphia, PA: W. B. Saunders & Co., 1991.en_US
dc.identifier.citedreferenceLamers CB, Froeling PG. Clinical significance of hyperparathyroidism in familial multiple endocrine adenomatosis type I (MEA I). Am J Med 1979; 66: 422 – 4.en_US
dc.identifier.citedreferenceMalmaeus J., Benson L., Johansson H., Ljunghall S., Rastad J., Akerstrom G., et al. Parathyroid surgery in the multiple endocrine neoplasia type I syndrome: Choice of surgical procedure. World J Surg 1986; 10: 668 – 72.en_US
dc.identifier.citedreferenceShepherd JJ. The natural history of multiple endocrine neoplasia type I. Arch Surg 1991; 126: 935 – 46.en_US
dc.identifier.citedreferenceDonow C., Pipeleers-Marichal M., Schroder S. Surgical pathology of gastrinoma: site, size, multicentricity, association with multiple neoplasia Type I and malignancy. Cancer 1991; 68: 1329 – 34.en_US
dc.identifier.citedreferenceThompson NW, Lloyd RB, Nishiyama RH, Vinik AI, Strodel WE, Allo MD, et al. MEN-I pancreas: A histological and immunohistological study. World J Surg 1984; 8: 561 – 74.en_US
dc.identifier.citedreferenceKloppel G., Willemer S., Stamm B., Hacki WH, Heitz PU. Pancreatic lesions and hormonal profile of pancreatic tumors in multiple endocrine neoplasia type I: An immuno-cytochemical study of nine patients. Cancer 1986; 57: 1824 – 32.en_US
dc.identifier.citedreferenceMacGillivay DC, Rushin JM, Zeiger MA, Shakir KMM. The significance of gastrinomas found in peripancreatic lymph nodes. Surgery 1991; 109: 556 – 62.en_US
dc.identifier.citedreferencePipeleers-Marichal M., Somers G., Willems G., Foulis A., Imrie C., Bishop AE, et al. Gastrinomas in the duodenums of patients with multiple endocrine neoplasia type I and the Zollinger-Ellison syndrome. N Engl J Med 1990; 322: 723 – 7.en_US
dc.identifier.citedreferenceVinik AI, Moattari AR, Cho K., Thompson NW. Transhepatic portal vein catheterization for localization of sporadic and MEN gastrinomas: A ten-year experience. Surgery 1990; 107: 246 – 55.en_US
dc.identifier.citedreferenceImamura M., Takahashi K., Adachi H., Minematsu S., Shimada Y., Naito M., Suzuki T., et al. Usefullness of selective arterial secretin injection test for localization of gastrinoma in the Zollinger-Ellison Syndrome. Ann Surg 1987; 205: 230 – 6.en_US
dc.identifier.citedreferenceDelcore R., Jr Cheung LY, Friesen SR. Characteristics of duodenal wall gastrinomas. Am J Surg 1990; 160: 621 – 4.en_US
dc.identifier.citedreferenceThorn AK, Norton JA, Axiotis CA, Jensen RT. Location, incidence and malignant potential of duodenal gastrinomas. Surg 1991; 110: 1086 – 93.en_US
dc.identifier.citedreferenceBornman PC, Marks IN, Mee AS, Price S. Favorable response to conservative surgery for extra-pancreatic gastrinoma with lymph nodes metastases. Brit J Surg 1987; 74: 198 – 201.en_US
dc.identifier.citedreferenceImamura M., Kanda M., Takahashi K., Shimada Y., Miyahara T., Wagata T., et al. Clinicopathological characteristics of duodenal microgastrinomas. World J Surg 1992; 16: 703 – 10.en_US
dc.identifier.citedreferenceSugg SL, Norton JA, Fraker DL, Metz DC, Pisegna JR, Fishbeyne V., et al. A prospective study of intraoperative methods to diagnose and resect duodenal gastrinomas. Ann Surg 1993; 218: 138 – 44.en_US
dc.identifier.citedreferenceShepherd JJ, Challis DR, Davies PF, McArdle JP, Teh BT, Wilkinson S., et al. Multiple endocrine neoplasia, type I: gastrinomas, pancreatic neoplasms, microcarcinoids, the Zollinger-Ellison Syndrome, lymph nodes and hepatic metastases. Arch Surgery 1993; 128: 1133 – 12.en_US
dc.identifier.citedreferencePasieka JL, Mcleod MK, Thompson NW, Burney RE. Surgical approach to insulinomas: Assessing the need for preoperative localization. Arch Surg 1992; 127: 442 – 7.en_US
dc.identifier.citedreferenceService FJ, McMahon MM, O'Brien PC, Ballard DJ. Functioning insulinoma-incidence recurrence and long-term survival of patients: A 60-year study. Mayo Clin Proc 1991; 66: 711 – 19.en_US
dc.identifier.citedreferenceAkerstrom G., Malmaes J., Bergstrom R. Surgical anatomy of human parathyroid glands. Surgery 1984; 95: 14 – 21.en_US
dc.identifier.citedreferenceBlock MA, Frame B., Jackson CF. The efficacy of subtotal parathyroidectomy for primary hyperparathyroidism due to multiple gland involvement. Surg Gynecol Obstet 1978; 147: 1 – 5.en_US
dc.identifier.citedreferenceLight GS, Hensley MI. Management of familial hyperparathyroidism. Prog Surg 1986; 18: 106 – 16.en_US
dc.identifier.citedreferencePrinz RA, Gamvros OI, Sellu D., Lynn JA. Subtotal parathyroidectomy for primary chief cell hyperplasia of the multiple endocrine neoplasia type I syndrome. Ann Surg 1981; 193: 26 – 9.en_US
dc.identifier.citedreferenceRizzoli R., Green J., III, Marx SJ Primary hyperparathyroidism in familial multiple endocrine neoplasia type I. Long-term follow-up of serum calcium levels after parathyroidectomy. Am J Med 1985; 78: 467 – 74.en_US
dc.identifier.citedreferenceThompson NW. The techniques of initial parathyroid explorative and reoperative parathyroidectomy. In: Thompson NW, Vinik AI, eds. Endocrine Surgery Update. New York, NY: Grune & Stratton, 1983: 365 – 83.en_US
dc.identifier.citedreferenceWells SA, Jr, Farndon JR, Dale JK, Leight GS, Dilley WG. Long-term evaluation of patients with primary parathyroid hyperplasia managed by total parathyroidectomy and heterotopic autotransplantation. Ann Surg 1980; 192: 451 – 8.en_US
dc.identifier.citedreferenceHeerden van JA, Kent RB, III, Sizemore GW, Grant CS, ReMine WH, Kent RB. Primary hyperparathyroidism in patients with multiple endocrine neoplasia syndrome. Surgical experience. Arch Surg 1983; 118: 533 – 6.en_US
dc.identifier.citedreferenceThompson NW, Eckhauser FE, Harness JK. Anatomy of primary hyperparathyroidism. Surgery 1982; 92: 814 – 22.en_US
dc.identifier.citedreferenceThompson NW, Vinik AI, Eckhauser FE. Microgastrinomas of the duodenum. A cause of failed operations for the Zollinger-Ellison syndrome. Ann Surg 1989; 209: 396 – 404.en_US
dc.identifier.citedreferenceThompson NW. The surgical treatment of the Zollinger-Ellison Syndrome in sporadic and MEN I Syndrome. Acta Chir Austriaca 1992; 24: 82 – 7.en_US
dc.identifier.citedreferenceThompson NW. The surgical treatment of the endocrine pancreas and Zollinger-Ellison syndrome in the MEN-I Syndrome. Henry Ford Hospital Med Journal 1992; 40: 195 – 198.en_US
dc.identifier.citedreferenceThompson NW, Bondeson AG, Bondeson L., Vinik AI. The surgical treatment of gastrinoma in MEN-I syndrome patients. Surgery 1989; 106: 1081 – 6.en_US
dc.identifier.citedreferenceDelcore R., Herumreck AS, Friesen SR. Selective surgical management of correctable hypergastrinemia. Surgery 1989; 106: 1094 – 102.en_US
dc.identifier.citedreferenceDelcore R., Friesen SR. Zollinger-Ellison Syndrome. A new look at regression of gastrinomas. Arch Surg 1991; 126: 556 – 8.en_US
dc.identifier.citedreferenceFriesen SR. Are' aberrant nodal gastrinomas' pathogenetically similar to ‘lateral aberrant thyroid’ nodules? Surgery 1990; 107: 236 – 8.en_US
dc.identifier.citedreferenceDelcore R., Friesen SR. The role of pancreatoduodenectomy of primary duodenal wall gastrinomas in patients with the Zollinger-Ellison Syndrome. Surgery 1992; 112: 1 – 8.en_US
dc.identifier.citedreferenceThompson NW, Pasieka J., Fukuuchi A. Duodenal gastrinomas, duodenotomy and duodenal exploration in the surgical management of Zollinger-Ellison Syndrome. World J Surg 1993; 17: 455 – 62.en_US
dc.identifier.citedreferencePipeleers-Marichal M., Donow C., Heitz PU, Kloppel G. Pathologic aspects of gastrinomas in patients with Zollinger-Ellison Syndrome with and without multiple endocrine neoplasia Type I. World J Surgery 1993; 17: 481 – 8.en_US
dc.identifier.citedreferenceCheruer JA, Sawyers JL. Benefit of resection of metastatic gastrinoma in Multiple Endocrine Neoplasia Type I. Gastroenterology 1992; 102: 1049 – 53.en_US
dc.identifier.citedreferenceAkerstrom G., Johansson H., Grama D. Surgical treatment of endocrine pancreatic lesions in MEN I. ACTA Oncologica 1991; 30: 541 – 5.en_US
dc.identifier.citedreferenceHeerden van JA, Smith SL, Miller L. Management of the Zollinger-Ellison Syndrome in patients with multiple endocrine neoplasia type I. Surgery 1986; 100: 971 – 6.en_US
dc.identifier.citedreferenceNorton JA, Doppman JL, Jensen RT. Curative resection in Zollinger-Ellison Syndrome: Results of a 10 year prospective study. Arm Surg 1992; 215: 8 – 18.en_US
dc.identifier.citedreferenceMignon M., Ruszniewski P., Podevin P., et al. Current approach to the management of gastrinoma and insulinoma in adults with multiple endocrine neoplasia I. World J Surgery 1993; 17: 489 – 97.en_US
dc.identifier.citedreferenceSheppard BC, Norton JA, Doppman JL, et al. Management of islet-cell tumors in patients with multiple endocrine neoplasia: a prospective study. Surgery 1989; 106: 1108 – 18.en_US
dc.identifier.citedreferenceSolcia E., Capella C., Fiocca R., Rindi G., Rosai J. Gastric argyrophil carcinoidosis in patients with Zollinger-Ellison Syndrome due to Type I multiple Endocrine Neoplasia. Am J Surg Pathol 1990; 14: 503 – 13.en_US
dc.identifier.citedreferenceNorton JA, Cornelius MJ, Doppman JL, Maton PN, Gardner JD, Jensen RT. Effect of parathyroidectomy in patients with hyperparathyroidism, Zollinger-Ellison syndrome and multiple endocrine neoplasia type I: A prospective study. Surgery 1987; 102: 958 – 66.en_US
dc.identifier.citedreferenceTisell LE, Ahlman H., Jansson S., Grimelius L. Total pancreatectomy in the MEN-I syndrome. Br J Surg 1988; 75: 154 – 7.en_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe its collections in a way that respects the people and communities who create, use, and are represented in them. We encourage you to Contact Us anonymously if you encounter harmful or problematic language in catalog records or finding aids. More information about our policies and practices is available at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.