Expulsion mechanism of xylitol 5-phosphate in Streptococcus mutans
dc.contributor.author | Pihlanto-Leppälä, Anne | en_US |
dc.contributor.author | Söderling, Eva | en_US |
dc.contributor.author | Makinen, Kauko K. | en_US |
dc.date.accessioned | 2010-06-01T18:34:17Z | |
dc.date.available | 2010-06-01T18:34:17Z | |
dc.date.issued | 1990-04 | en_US |
dc.identifier.citation | PIHLANTO-LEPPÄLÄ, ANNE; SÖDERLING, EVA; MÄKINEN, KAUKO K. (1990). "Expulsion mechanism of xylitol 5-phosphate in Streptococcus mutans." European Journal of Oral Sciences 98(2): 112-119. <http://hdl.handle.net/2027.42/71776> | en_US |
dc.identifier.issn | 0909-8836 | en_US |
dc.identifier.issn | 1600-0722 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/71776 | |
dc.description.abstract | The expulsion mechanism of xylitol 5-phosphate in Streptococcus mutans ATCC 25175 was studied using resting cells incubated in the presence of 14 C-xylitol. The expulsion appeared to be a two-step process: xylitol 5-phosphate was first hydrolyzed to xylitol and inorganic phosphate, and the xylitol was subsequently expelled from the cells. The dephosphorylation step appeared to be energy-requiring and it was most likely associated with a phosphatase which was active on xylitol 5-phosphate. Two to three successive cultivations of the cells in the presence of 6% xylitol increased this enzyme activity 4.3-fold. These results are in accordance with the presence of an energy-dependent xylitol 5-phosphate cycle in S. mutans , which is regulated by exogenous xylitol. | en_US |
dc.format.extent | 668831 bytes | |
dc.format.extent | 3109 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Ltd | en_US |
dc.rights | Munksgaard 1990 | en_US |
dc.subject.other | S. Mutans | en_US |
dc.subject.other | Xylitol | en_US |
dc.title | Expulsion mechanism of xylitol 5-phosphate in Streptococcus mutans | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Dentistry | en_US |
dc.subject.hlbsecondlevel | Otolaryngology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | School of Dentistry, The University of Michigan, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationother | Department of Biochemistry, Institute of Dentistry, Univrsity of Turku, Turku, Finland | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/71776/1/j.1600-0722.1990.tb00949.x.pdf | |
dc.identifier.doi | 10.1111/j.1600-0722.1990.tb00949.x | en_US |
dc.identifier.source | European Journal of Oral Sciences | en_US |
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dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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