Biochemical Diagnosis and Localization of Pheochromocytoma
dc.contributor.author | Grossman, Ashley | en_US |
dc.contributor.author | Pacak, Karel | en_US |
dc.contributor.author | Sawka, Anna | en_US |
dc.contributor.author | Lenders, Jacques W. M. | en_US |
dc.contributor.author | Harlander, Debra | en_US |
dc.contributor.author | Peaston, Robert T. | en_US |
dc.contributor.author | Reznek, Rodney | en_US |
dc.contributor.author | Sisson, James C. | en_US |
dc.contributor.author | Eisenhofer, Graeme | en_US |
dc.date.accessioned | 2010-06-01T18:55:08Z | |
dc.date.available | 2010-06-01T18:55:08Z | |
dc.date.issued | 2006-08 | en_US |
dc.identifier.citation | GROSSMAN, ASHLEY; PACAK, KAREL; SAWKA, ANNA; LENDERS, JACQUES W. M . ; HARLANDER, DEBRA; PEASTON, ROBERT T . ; REZNEK, RODNEY; SISSON, JAMES; EISENHOFER, GRAEME (2006). "Biochemical Diagnosis and Localization of Pheochromocytoma." Annals of the New York Academy of Sciences 1073(1 Pheochromocytoma: First International Symposium ): 332-347. <http://hdl.handle.net/2027.42/72111> | en_US |
dc.identifier.issn | 0077-8923 | en_US |
dc.identifier.issn | 1749-6632 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/72111 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=17102103&dopt=citation | en_US |
dc.description.abstract | Pheochromocytomas can have a highly variable presentation, making diagnosis challenging. To think of the tumor represents the crucial initial step, but establishing the diagnosis requires biochemical evidence of excessive catecholamine production and imaging studies to localize the source. Currently, however, there exist no generally agreed upon guidelines based on which tests and testing algorithms should be used to confirm and locate or exclude a suspected pheochromocytoma. Choice of biochemical tests and imaging studies instead usually depends on institutional experience. At the First International Symposium on Pheochromocytoma (ISP2005), held in Bethesda in October 2005, a panel of experts and patient representatives discussed current problems and available options for tumor diagnosis and localization and formulated recommendations, which were subsequently agreed upon by those in attendance at the meeting. This article summarizes the discussion and recommendations derived from that session. | en_US |
dc.format.extent | 210611 bytes | |
dc.format.extent | 3109 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.publisher | Blackwell Publishing Inc | en_US |
dc.rights | 2006 New York Academy of Sciences | en_US |
dc.subject.other | Pheochromocytoma | en_US |
dc.subject.other | Biochemical Diagnosis | en_US |
dc.subject.other | Metanephrines | en_US |
dc.subject.other | Catecholamines | en_US |
dc.subject.other | Localization | en_US |
dc.subject.other | Computed Tomography | en_US |
dc.subject.other | Magnetic Resonance Imaging | en_US |
dc.subject.other | MIBG | en_US |
dc.subject.other | Positron Emission Tomography | en_US |
dc.title | Biochemical Diagnosis and Localization of Pheochromocytoma | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Science (General) | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Radiology, University of Michigan Hospitals, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationother | Department of Endocrinology, St. Bartholomew's Hospital, West Smithfield, London, UK | en_US |
dc.contributor.affiliationother | Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA | en_US |
dc.contributor.affiliationother | Department of Medicine, University of Toronto, Toronto, Ontario, Canada | en_US |
dc.contributor.affiliationother | Department of General Internal Medicine, St. Radboud University Hospital, Nijmegen, the Netherlands | en_US |
dc.contributor.affiliationother | Pheochromocytoma Support Group, Camden, New York 13316, USA | en_US |
dc.contributor.affiliationother | Department of Clinical Biochemistry, Freeman Hospital, Newcastle upon Tyne, UK | en_US |
dc.contributor.affiliationother | Division of Radiology, St. Bartholomew's Hospital, West Smithfield, London, UK | en_US |
dc.contributor.affiliationother | Clinical Neurocardiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA | en_US |
dc.identifier.pmid | 17102103 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/72111/1/annals.1353.038.pdf | |
dc.identifier.doi | 10.1196/annals.1353.038 | en_US |
dc.identifier.source | Annals of the New York Academy of Sciences | en_US |
dc.identifier.citedreference | Platts, J.K., P.J. Drew & J.N. Harvey. 1995. Death from phaeochromocytoma: lessons from a post-mortem survey. J. Roy. Coll. Physicians Lond. 29: 299 – 306. | en_US |
dc.identifier.citedreference | Lo, C.Y. et al. 2000. Adrenal pheochromocytoma remains a frequently overlooked diagnosis. Am. J. Surg. 179: 212 – 215. | en_US |
dc.identifier.citedreference | McNeil, A.R. et al. 2000. Phaeochromocytomas discovered during coronial autopsies in Sydney, Melbourne and Auckland. Aust. N. Z. J. Med. 30: 648 – 652. | en_US |
dc.identifier.citedreference | Kaltsas, G.A., D. Papadogias & A.B. Grossman. 2004. The clinical presentation (symptoms and signs) of sporadic and familial chromaffin cell tumours (phaeochromocytomas and paragangliomas). Front. Horm. Res. 31: 61 – 75. | en_US |
dc.identifier.citedreference | Sjoerdsma, A. et al. 1959. Studies on the biogenesis and metabolism of norepinephrine in patients with pheochromocytoma. J. Clin. Invest. 38: 31 – 38. | en_US |
dc.identifier.citedreference | Crout, J.R. & A. Sjoerdsma. 1964. Turnover and metabolism of catecholamines in patients with pheochromocytoma. J. Clin. Invest. 43: 94 – 102. | en_US |
dc.identifier.citedreference | Eisenhofer, G. et al. 2003. Pheochromocytoma: rediscovery as a catecholamine-metabolizing tumor. Endocr. Pathol. 14: 193 – 212. | en_US |
dc.identifier.citedreference | Eisenhofer, G. et al. 1999. Plasma normetanephrine and metanephrine for detecting pheochromocytoma in von Hippel-Lindau disease and multiple endocrine neoplasia type 2. N. Engl. J. Med. 340: 1872 – 1879. | en_US |
dc.identifier.citedreference | Raber, W. et al. 2000. Diagnostic efficacy of unconjugated plasma metanephrines for the detection of pheochromocytoma. Arch. Intern. Med. 160: 2957 – 2963. | en_US |
dc.identifier.citedreference | Lenders, J.W. et al. 2002. Biochemical diagnosis of pheochromocytoma: which test is best ? JAMA 287: 1427 – 1434. | en_US |
dc.identifier.citedreference | Sawka, A.M. et al. 2003. A comparison of biochemical tests for pheochromocytoma: measurement of fractionated plasma metanephrines compared with the combination of 24-hour urinary metanephrines and catecholamines. J. Clin. Endocrinol. Metab. 88: 553 – 558. | en_US |
dc.identifier.citedreference | Sawka, A.M. et al. 2004. A systematic review of the literature examining the diagnostic efficacy of measurement of fractionated plasma free metanephrines in the biochemical diagnosis of pheochromocytoma. BMC Endocr. Disord. 4: 2. | en_US |
dc.identifier.citedreference | Unger, N. et al. 2006. Diagnostic value of various biochemical parameters for the diagnosis of pheochromocytoma in patients with adrenal mass. Eur. J. Endocrinol. 154: 409 – 417. | en_US |
dc.identifier.citedreference | Gardet, V. et al. 2001. Lessons from an unpleasant surprise: a biochemical strategy for the diagnosis of pheochromocytoma. J. Hypertens. 19: 1029 – 1035. | en_US |
dc.identifier.citedreference | Gerlo, E.A. & C. Sevens. 1994. Urinary and plasma catecholamines and urinary catecholamine metabolites in pheochromocytoma: diagnostic value in 19 cases. Clin. Chem. 40: 250 – 256. | en_US |
dc.identifier.citedreference | Davidson, D.F. 2002. Phaeochromocytoma with normal urinary catecholamines: the potential value of urinary free metadrenalines. Ann. Clin. Biochem. 39: 557 – 566. | en_US |
dc.identifier.citedreference | Guller, U. et al. 2006. Detecting pheochromocytoma: defining the most sensitive test. Ann. Surg. 243: 102 – 107. | en_US |
dc.identifier.citedreference | Sawka, A.M. et al. 2004. The economic implications of three biochemical screening algorithms for pheochromocytoma. J. Clin. Endocrinol. Metab. 89: 2859 – 2866. | en_US |
dc.identifier.citedreference | Brown, M.J. & D.J. Allison. 1981. Renal conversion of plasma DOPA to urine dopamine. Br. J. Clin. Pharmacol. 12: 251 – 253. | en_US |
dc.identifier.citedreference | Eisenhofer, G. et al. 2005. Biochemical and clinical manifestations of dopamine-producing paragangliomas: utility of plasma methoxytyramine. J. Clin. Endocrinol. Metab. 90: 2068 – 2075. | en_US |
dc.identifier.citedreference | Ross, G.A. et al. 1993. Plasma and 24 h-urinary catecholamine concentrations in normal and patient populations. Ann. Clin. Biochem. 30 ( Pt. 1 ): 38 – 44. | en_US |
dc.identifier.citedreference | Sawka, A.M. et al. 2005. Measurement of fractionated plasma metanephrines for exclusion of pheochromocytoma: can specificity be improved by adjustment for age ? BMC Endocr. Disord. 5: 1. | en_US |
dc.identifier.citedreference | Eisenhofer, G. et al. 1995. Plasma metadrenalines: do they provide useful information about sympatho-adrenal function and catecholamine metabolism ? Clin. Sci. (Lond.) 88: 533 – 542. | en_US |
dc.identifier.citedreference | Eisenhofer, G. et al. 2003. Biochemical diagnosis of pheochromocytoma: how to distinguish true- from false-positive test results. J. Clin. Endocrinol. Metab. 88: 2656 – 2666. | en_US |
dc.identifier.citedreference | Brown, M.J. et al. 1981. Increased sensitivity and accuracy of phaeochromocytoma diagnosis achieved by use of plasma-adrenaline estimations and a pentolinium-suppression test. Lancet 1: 174 – 177. | en_US |
dc.identifier.citedreference | Bravo, E.L. et al. 1981. Clonidine-suppression test: a useful aid in the diagnosis of pheochromocytoma. N. Engl. J. Med. 305: 623 – 626. | en_US |
dc.identifier.citedreference | Mulinari, R.A. et al. 1987. The clonidine test for the diagnosis of pheochromocytoma: the usefulness of urinary metanephrine measurements. Braz. J. Med. Biol. Res. 20: 43 – 46. | en_US |
dc.identifier.citedreference | Neumann, H.P. et al. 2002. Germ-line mutations in nonsyndromic pheochromocytoma. N. Engl. J. Med. 346: 1459 – 1466. | en_US |
dc.identifier.citedreference | Amar, L. et al. 2005. Genetic testing in pheochromocytoma or functional paraganglioma. J. Clin. Oncol. 23: 8812 – 8818. | en_US |
dc.identifier.citedreference | Remine, W. et al. 1974. Current management of pheochromocytoma. Ann. Surg. 179: 740 – 748. | en_US |
dc.identifier.citedreference | Troncone, L. et al. 1990. The diagnostic and therapeutic utility of radioiodinated metaiodobenzylguanidine (MIBG): 5 years of experience. Eur. J. Nucl. Med. 16: 325 – 335. | en_US |
dc.identifier.citedreference | Peppercorn, P.D., A.B. Grossman & R.H. Reznek. 1998. Imaging of incidentally discovered adrenal masses. Clin. Endocrinol. (Oxford) 48: 379 – 388. | en_US |
dc.identifier.citedreference | Grumbach, M.M. et al. 2003. Management of the clinically inapparent adrenal mass (“incidentaloma”). Ann. Intern. Med. 138: 424 – 429. | en_US |
dc.identifier.citedreference | Eisenhofer, G. et al. 2005. Pheochromocytoma catecholamine phenotypes and prediction of tumor size and location by use of plasma free metanephrines. Clin. Chem. 51: 735 – 744. | en_US |
dc.identifier.citedreference | Francis, I. & M. Korobkin. 1996. Pheochromocytoma. Adv. Uroradiol. 34: 1101 – 1112. | en_US |
dc.identifier.citedreference | Goldstein, R.E. et al. 1999. Clinical experience over 48 years with pheochromocytoma. Ann. Surg. 229: 755 – 764; discussion 764–766. | en_US |
dc.identifier.citedreference | Sahdev, A. et al. 2005. CT and MR imaging of unusual locations of extra-adrenal paragangliomas (pheochromocytomas). Eur. Radiol. 15: 85 – 92. | en_US |
dc.identifier.citedreference | Mukherjee, J.J. et al. 1997. Pheochromocytoma: effect of nonionic contrast medium in CT on circulating catecholamine levels. Radiology 202: 227 – 231. | en_US |
dc.identifier.citedreference | Quint, L.E. et al. 1987. Pheochromocytoma and paraganglioma: comparison of MR imaging with CT and I-131 MIBG scintigraphy. Radiology 165: 89 – 93. | en_US |
dc.identifier.citedreference | Varghese, J.C. et al. 1997. MR differentiation of phaeochromocytoma from other adrenal lesions based on qualitative analysis of T2 relaxation times. Clin. Radiol. 52: 603 – 606. | en_US |
dc.identifier.citedreference | Furuta, N. et al. 1999. Diagnosis of pheochromocytoma using [123I]-compared with [131I]-metaiodobenzylguanidine scintigraphy. Int. J. Urol. 6: 119 – 124. | en_US |
dc.identifier.citedreference | Ilias, I., B. Shulkin & K. Pacak. 2005. New functional imaging modalities for chromaffin tumors, neuroblastomas and ganglioneuromas. Trends Endocrinol. Metab. 16: 66 – 72. | en_US |
dc.identifier.citedreference | Miskulin, J. et al. 2003. Is preoperative iodine 123 meta-iodobenzylguanidine scintigraphy routinely necessary before initial adrenalectomy for pheochromocytoma ? Surgery 134: 918 – 922; discussion 922–923. | en_US |
dc.identifier.citedreference | Hoegerle, S. et al. 2002. Pheochromocytomas: detection with 18F DOPA whole body PET: initial results. Radiology. 222: 507 – 512. | en_US |
dc.identifier.citedreference | Pacak, K. et al. 2001. 6-[18F]fluorodopamine positron emission tomographic (PET) scanning for diagnostic localization of pheochromocytoma. Hypertension 38: 6 – 8. | en_US |
dc.identifier.citedreference | Shulkin, B.L. et al. 1999. Pheochromocytomas: imaging with 2-[fluorine-18]fluoro-2-deoxy-d-glucose PET. Nucl. Med. 212: 35 – 41. | en_US |
dc.identifier.citedreference | Mann, G.N. et al. 2006. [(11)C]metahydroxyephedrine and [(18)F]Fluorodeoxyglucose positron emission tomography improve clinical decision making in suspected pheochromocytoma. Ann. Surg. Oncol. 13: 187 – 197. | en_US |
dc.identifier.citedreference | Trampal, C. et al. 2004. Pheochromocytomas: detection with 11C hydroxyephedrine PET. Radiology 230: 423 – 428. | en_US |
dc.identifier.citedreference | Mediavilla Garcia, J.D. et al. 1999. A comparative study of 9 cases of adrenal pheochromocytoma and 11 cases of extra-adrenal pheochromocytoma. Rev. Clin. Esp. 199: 343 – 348. | en_US |
dc.identifier.citedreference | Kaltsas, G. et al. 2001. Comparison of somatostatin analog and meta-iodobenzylguanidine radionuclides in the diagnosis and localization of advanced neuroendocrine tumors. J. Clin. Endocrinol. Metab. 86: 895 – 902. | en_US |
dc.identifier.citedreference | Chew, S.L. et al. 1994. Bilateral phaeochromocytomas in von Hippel-Lindau disease: diagnosis by adrenal vein sampling and catecholamine assay. Q. J. Med. 87: 49 – 54. | en_US |
dc.identifier.citedreference | Pacak, K. et al. 2001. A “pheo” lurks: novel approaches for locating occult pheochromocytoma. J. Clin. Endocrinol. Metab. 86: 3641 – 3646. | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.